@simulated.1
TATGTACTGTACAGTTTCATAACGCCGGATGTCTATCGATAGGGGGGCTTTCTTTTCACTCAGAATCCGGCAAAGACTACGTAAGAGCTGCCAATACCCGTTCGGATTCAATGCAGGAGCTCGCGTAAGGAATTATTTTATACCCGATTTAAGGGAGCATATGGATCACCCTCGGGAACATTTCAAGTGGCAACGAACGTACGCTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTGAGCAGTGACCGAAGGTAGGAAGCGACACACAATGCCATGCAATATAATTAGATGCCTGCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGACGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGGAAGATTCTGCCTCGAACATGACCAGAA
+
@86:6<7=::47:9I-&=69I):4I'I(=7958@76;)6;8II<0*&<I1'5I:+&1>54>8:I,:I'I(4I.&62:4<99<I*/<75:3I'I(4=I2(7I*6I(4I)9I(;78:I(:63:9::6.I(I(I'I(4I=,'577I/'88I4)I)I/'9=:7857I)65<2I-&89I-&I'87I/';I(<<I(4I(;8G'76%666<740<68;I(5/:I(I)75I(58:775I(6534;687888I(6:99I(47;878@796I)?I'I(94G'I(6;9675859I(79G'<576I(968I)I(<;;=/I(25I(II5+'678:7;I(359I(8:556I(<8;6I)8I(G'::454I0'87>&1I0'4I.&49I(;G';I'G'7E&5:7I(44;I<,&I+34I(:58I'698H';<77&I(5:I(
@simulated.2
TCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTGTGCGCGTTCTGCATGGACTATGCGACTAAGGATCCAGCCGAGAATTTGACGTGACACCCGGCCTATCTCGACAGGGTTTGCTAGGCCATTTTTGCGACACACCCGAATCCTCCTATCCCAAGATGATTTTGTGCGTCCAGATTATACGATCGGGCATTGTCGAAAATTCCTTAATAAGCGATTGCCAGAAGTGTATGGCACTCCCGCTGTTAGCCGGGCCGGTGCCGGCTACCCCCCAAGCTACGGAAGTCAAGGCAATCCACGC
+
4829638;I1(85854I.&6175;3:9I(E&8I);6625I(04:<97I1(7;;I)E&6I-&5663I0'6;F';38I7*&I(3=I(9:;<546I;+&76I'I(I(0I'96F&7::785465I)5;74:6I'5;9A;;:9369I)I,:7I(7;G'26:H'I1'586698:69I.&I(I,<865289::5I/'I0'7709D&I)3II2*&8;47866;I1(6F'8I'>F&62>I.'I'6246<I;+&1659:5I);73I(8:<&77:5I0':6I):797I>,'I)I'H'I'4I)68;7I)9F':9I(9;89:4I(74:<I/'657:I*;4I'I-&I(I(<7I(I';58II</)&I(5;98=I'I(9>:I(I(;I(>H'6885
@simulated.3
TGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATAGGAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCATACCCAGATGAACGCTGTCAAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTTAAGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTA
+
7669874=:;::77H'9I+967I3(5758H'=52I(748I)4I(I)765I(556;3:6;:5;;I@-'61H';&H'8:<65<98I(G';4I)33I@-'H'99742I(=I(5:I.&70<I(96:I)I3(68I1(858H'5;8;F'878<I'7688;=45I'887=78:85I/'48;65H'1348667I=,';74I'8I'458I/'<724:8I)I(9885:<28714795:9I.'9I'794H'6I;+&;<8857744H'I(9:H'I(888:65I0'I.&79@=72:I(44I'<I.&I*I'56I(I*8;646741<I2(<C:8I'I.&78I1(I(I/'67I(H'H'I(648554I)57I(I)5:87I(86=77I(2G':I(H'896H';:4I(6
@simulated.4
CTCCATGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGGCAACTCTGGAACCCGTTCTGTTCGTCTTGCCATGATACGACGCTTCCATATTGCAGACATTGGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTGAATGAAGGAGGTGATCTTTTTGGCTTAAATCGTTTGCTTTAACGCCTTAGAACACGGATTTTGCGAAGATAGGCGCAGGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGATAAGCGGAGCGAAAGATAGGATACGAAGGCGCTTTATCGCGTTGAGAACCCATGTGAAGTACACTATTTGATGCGGCACCTGTGCCGAAACTTCGTCGTCACCTGATGCCAACACAAAGT
+
3<G'8448664I/'6I/'7963353I(859:I)>9668I*9797<I(4I(=:45H'I'I1(9I(;9<I(3<88H'5F'88;<<5677858H'I(745I'374;3::I(I)=8I)F&48I(:7>79I:+&:I(48;I/'7I*88;639:>768I(26I0'8:876H'65I(8:I)58I)F'=I(972;9II5,'I'8H'I2(873I2(6<I0'H'78I(H'5=I)977I(6I>,'869H'7877G':98:II3*&668/986;I(599:I)8676I'3I)I/'II2*&88I':<H'8668I3(879;I(86638I(I(8=;I.&9898;4I(985G'I0':7994I(8C:639<:I-&73978I)6>I'8=9>G'7I.&5I'39874464I'554D:D&I(86?I/'?9
@simulated.5
AAACAACACTAAGTGTAACGGAGGTGGTACATAAGCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGGCTCACTCCCCTTGAGACGGCTATGCGTTGTATTCCACCCCGAGACCTTGTCCCTTGCCACAGTATGATCGAGAATGACTAACTGGGCCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAGACTCAGGTGTACCTGGAGTAGAAAAATAGGATCTCAAGCACTATGATCAGGTGATATTTGCTAATAA
+
I0'7I(3757H'52;5G'8I)8I(1F&94786I(79919I(:;668473I(I'I1(I(8I)67I'I'52:66684H'6<8:99:9;906587I)897;I'77I/'529978I=,'I(:;645I(5672478G';<4I)G'7I<,'358?I(I(45I/'I(7I(286995867=>968I)59:97I'<3I-&I/'I)8;2I8*&9991H'6I'I)I(7I)2;4I'4868I*I(568684>677=I(I*;65I)I/'9I(5:?G'55254I'9;I*I(579I(7;>F'=<767F'4I(9I)2;6I(25<I'=:82779:F':76:I9+&74I(8664947:I'5I(:I/'I.&58';87H'6481I);H'48:9;II4+':7I':2799I(98754555:6:8I'687:6I1(899I(6I)
@simulated.6
GCAAGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGATTGCATGTGCGTTGCACAACCACTACAAAGGAAGCCTCGAGATCATGGGCCCGTCGGCGGCATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACAATGATCGTACGCAGGCGCGCGCATTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTT
+
27I'I+6I*I0':88I(;7693I*86I*7I.'I2(G'89<788747I)<H'98I)572686;7:94;I6*74I(F'H'I'I(653295547G'7I)I(5;I)6E&989H'I(66I*5I.'4998:I'8:37877;65I.&:I(5G'3;273876976I)8<<I3(745I(578;9=H'888I'I(;I*:/7G'4:7966686I(7?88I(I(46473I0'I(I(9F'559854D54;I.&I.&><4G'9I(863:>78:I)I'634330I(:I(8I(I(7=I'8I)47I(5/I(9;9:F'3:489:5978I(I(I0'55I(8;5G';I.&58=97:7E&=?99<3<=6864I'8=475913I,7I(6572I(G'I)357I(8I(I/';I(I(377I(3I0'
@simulated.7
CAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTTCTCAGACCTTCTCTGTTCATAAAACTTACGCACTGATGCACCCCGGATAGCCCTTCAGGGTAGGTGTCTAGATATGCGAGCGACCGACGACTTATAGTCAGCTACGGTCCCTCAATGGCCTGATGCCTTTAATCCCTAGCGGCGGGTGTAGCGGGTCGACTAGGCACCAGGTCAGCAACCTGACTAGAAGCGGGGTCAAGCGTGTTTAGGCTGGGCATTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAAACCAGTGCTAGTGCATGAAGCCGACGTATACAGACTAGCTAGGGGCCTACGCGCATTAGCCGAATGCCCGATGCC
+
4:9254478;26747868I/'>;271889958I'8=7758;3<<4:9<6G':<6:597891H'6E&H'9:F&9:5I):I(;I)I.&I'77595@I(I(68689F';59IA-(8I)9:5:2%0::7958I>,'G'9686I/'I(:2I-&64I(9883;648;6<775:7749I(559B84I(893477624:71I(7I1(;4H'5I(I,176:3I(I-&I(8I/'4;47H'9I/'8::8<9I4)77:55>6I)96G'9I)9;778H'H'9865447I'.6I;+&:9I(;4065I1'3I(44I/'>=I)9C4777679778;I)I.'53847:3I(77I):4999897I;+&I'6)595867:857:?E&1I(;8C4:<8<;799746:385I@-'F'79856=:4I)>8I(7I'49I7*;:76I)
@simulated.8
CGACTACGGAGCGCTCAAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGATCGGGTGTACTAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTACGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGAT
+
86424:7I*7862;:4I(43I(I.&I)2I0'7;6H'74247:2I(I'I*67I(IH0)%7955I(79I)I1(I(I(9656:6I.&6699G'413797:I'867<8;>595867759I'66726<I/'I(2I9+&27I'6I2(93855I-&:657'95I4)=5;:>88I(798I0'93:64:=64;867=I(977=75I0'9I(5:I(776I)867I(498947763:878665<6>I3(:6<I-&65I(75;8H'46886:4I/'I?-'4I()368059:3879-I(I2(866I(497I8*&5IH0)%68:7I'39;I)7I(<6997:2G'<I-&971487I'6899078;;896977I/':47I(74I(I(5:
@simulated.9
CCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGTGGATTATGCTATGCTGTCCAGGTACCTAGCTACTAGACGATGCAAACAACCGAATGTAGCCAAGATTCCAAGGCAATGTATCACGCGATTCACTGGCTGTCGGCTGCGTCGTTGTATTCATTAGGGTAAGTCATACAACTAATATTCACTTTAAATTGACTAACCGGGCCACAGAAGGTTAGCCCCCGTGAGCACAGACAACTCAGATAGACAAGCCTCACGCGACCACCCGTGGGTAGAAGACTTTTGACGTTAATCTTAAA
+
I(8I(6:70465;3866I'>G'8:36753=3=I'528I'6;8:>8;:59=98I(99<>I'6==26;H'2:84789489I(6:I/'6I'4;II1*&626=653;85I(<27294@I):=I(:489<64I'I1(4;297367I(856IF/)9I(7I)8;56773674:5I(4I(8:F&7<94274::846881<;I-&9H'I':F'7884<I(I'5;H'I(I'I(:I)<375982646=0I(4769I(38968I(8371*85;I(676H'<:I(3I0'4I(496<?87I(86H'95H'8;0I/'I-&I(<:59I*I(I-&I(934:I'I,F&5:II3*&367:9767=:;4I(665887:3488E&7I(8;;97979I)9I/'36I0'464I'5==I:+&4873I(I'8:H'I0'
@simulated.10
ACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAGTTAGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGAGTGCTTAAATCTAAGACCCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGTCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTATGCTATGCTGTCCAGGTACCTAGCTACTAGACGATGCAAACAACCGAATGTAGCCAAGATTCCAAGGCAATGTATCACGCGATTCACTGGCTGTCGGCTG
+
7<7I(37I(9<H'6:<29I(<I)I)79885I'374I(827H'::35:1IG0)%:5I=,'53:875675:876I'8649I/'5I?-'6F'7I4)9566<98?G'I0'G':5I(:148:7I>-';H'I)59I'7=98/563H'I.'57:I(7>I;+&I1(4I0'86I9+&8H'=586:7675768H'3I(76=3:874<4G';86I(7:26896748>69G';3:8I(968:<5D&6=7874:316I)56I0'8I(64II1)&;597<736;9I'93:8665+I(47I)27477<8I*I.&69776::<I(;8;II0)&;I(;H'386;727:;73>I(=I'9:G'9/:;;4;68.83889?8I0'7I(I'6I):72;7I'H'89I)I(I(I(;F'637:73695658I'6949I(8=9>:I(784
@simulated.11
TGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATGCAAGGTTTGATGGGTTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTGGTGAAAAACACGTGGAGCTCGCGTTCATTACGCTGAACAGTAGTCATTCCACTAACGGTATCATGGAATAATACTATTGCGAGCTCTTGAAACATTACAAAGGGC
+
68:I)75I(28=;I(55:665323I(<:838I':07I*16I)I(:I/'8D9<=5:8II8-(%528<4:8583I)6544I/'5:5I'9I(57;6H'9786I:+&9F'I.&694I(>35H'C7>I'I(I3(996I2(F'I'<4557=;796;=I0'98:G'4I(I(3I)9;13F'=F&56847>86654I(B:437I(I(73<I-&I/'59>876H'6388I'I(I'76:9I(I(68:=5;:I1(37I/'9I0'H'I(6I(6I'8875:4:<I1(5848665I8*&DG'4I(99;I-&9:<75;8478G'86I(;:49653I(548I0'4;7<3I(5I(9I0'9H'27II3+':7758H'24673>96G'78I(9:7<69I)7577:8487I)I(98<E&<I'679457I(I(:I(474:9I(6:983;30I(:I/'87I(8:I1(I0'8
@simulated.12
TCCACCGGTAGTGTACGATCAATGTGGTGCCCGAGTGTTTCATGGACAATCACGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGCAACCCGAACCTAGTGGATCGATTACGGGATAGCCCCCTGCCTTTAGCTGCGAATCTCAGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGGCCCCTAAGACAAGGCATACGCTGGGTCAATGGATTCGAATAGCAAGTGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATAGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTG
+
9I):I,I(;:;77:%3;554G'59=H'<:I0'26958I-&4;3H'77I(847:=8I(G'I(=6I);7I(I(6;875I'987I(<756;8E&DG'887H'9:39:79I(I'H';8I/'368I:+&9I'I5)'G'I)6845H'56;3;I):5I.&5675II3*&:6I)I/'486891AG';98449<58I(368I/'9>I,&I0'486I)6H'/8::464I)I/'1E&I(;839<5;3E&I@-'7I(6;3I(I'50>7?5:6I.'65I)7I'5I)49I*7'72G'%=4:8=4917I(68I(94979:4476997I)86893G'5H'7F&597I(;I,&:7:966:9I/'7I/'I(557I(I)?599<I':I0'/678;4697I'8
@simulated.13
AGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTTAAGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAATAGTGGTGGAACAGTGCGCGCGAAGGGAGACTCCACCCGGTAGTGTCGATCAATGTGGTGCCCGAGTGTTTCATGGACAATCACGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATT
+
<:I(I)6979=<7684<86747I3(7I(886I)4I8*&6=976<:78I)I(:5I(I)6696;6I/'I/'57387A0I(5:F'7I0'F'H'74H'I'<59176:6=I-&9739I'I-&87I0'I(I,:<I(I)H'I':5:8::I(<;I(H'8=72I(7;695I(1I):I(I'567G';76I'6<I*8I(I(8G'=7565685;;I(4=;55596I(298;I)5I(I(=94;75874;7I'I2(7B);9G'6I,&I(346968;7:68H'88;I(57I0'<86=:I.&:96I(@5I'<5:7;:I)H'I(79G'09I)H':93:8H'867I)466888F&I'I'528H'<8487:8I)I)I(64I(
@simulated.14
GAGTGGGTAATGCCTTCGCACGTGGTCAACTGTCGCGTTTGCCGCTAGTACGGTGATCACTTGGAGCCGCCCTACTCCTAGCGATCGTCAAGGGTACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCATCAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAAGCGCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTCGCAAAATCCGTGTTCTAAGGCGTTAAAGCAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGA
+
85;;I/'9I(98F'G'99<B:&<I)7;G'61778;39I/'4I'=68:74(7I*8684747I(I':7I)>I4)4871I)965<96;8879I*I.&88<I2(8;5I*I(?H'48:I)<<465:5;F'7I0';I'6186I(64G':6675I1(:;;8/6I)9I(;5818I0'I(88;I':336>8I.';6;DF'79:88I(39:=I/'5447I)94I(69II1)&I/'I'8I'7988I)276CI'8<299785II1*&7564I)1389D:86I8*&:I(364G'95I+I)85I(I0'63I+958I1'G'7I(II2*&;7697I(9I*E&7@H'57I(9:G':<>46I,96H'38668688965I)>I/'7:7I)4I<,'5775
@simulated.15
TAAGTTTTATGAACAGAGAAGGTCTGAGAAGGGTCCAGGCGGACACCTGCCTTGAAGTGACGACATGGTAGTATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCCTACGCCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGTAAT
+
:I)5I@-'6:8G'5=47;I(I'55:;25I*I2((I(7F&8I(876G'44I)I):I'755876;646I)298,:4<62:8;841<I(;8=79=77866I.&567788488;:486;59I7*&79;88:6I.'25;:I'I1(I-&5I'I'5577I(H'5996<I(4<I(47:;I(?<4975>4939I)49I(7I/'96H'6?6G'973F'<=1447985F':94:96<3?6;I);:94876524I/'6I(I)8882I0'6?9I(II:.)&868I'846I)88I'77I(67::3575I(9;354438I'4I.&5=I.&<877935H'6775547I0':4<55I-&46973::;I'I'4H'78916&I)<
@simulated.16
CTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTCGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCATAGGGGGCTTCTTTTCACTCAGAAATCCGGCAAAGACTACGTAAGAGCTGCCAATACCCGTTCGGATTCAATGCAGGAGCTCGCGTAAGGAATTATTTTATACCCGATTTAAGGGAGCATATGGATCACCCTCGGGAACATTTCAAGTGGCAACGAACGACGCTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTGAGCAG
+
863E&974:76I/'2F&96I(956I(;:8I(<87:8059:987669;458I0'66:I.'9=I'9675G'875;68;I.&I:+&<I':8:8998B67:6I(I0'795H'6;5I<,'7II0)&9966I(:96I(>G'6=877:4H'3I.'09=936I(9:::8576443;:55I0'7;8I'39I(E&7?655;442579II6,(8I,:I8*&7772586I1(7I'H'7I.&87=;7:85H'6=:598I*I)87I.'9I)7I(2I)>G';4;:E&886989;68I(I(I(H';I=,'698I/'45I7*I)I-&:5;9658I)=7:7I0';7I/'I(57I-&7H'97I);I(67F&78<6:8778<689I(964G'I(85I(97535;E&7978:4:978;I(96:8I)6683755
@simulated.17
AATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTCCGCGTGATTGTCCATGAAACACTCGGGCACCACATTGATCGACACTACCGGGTGGAGCCTCCCTTCGTCGCGCACTGTTCCACCACTATTCGCTATCATTCGTACTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGTCACTTCAGACCTTGACCTGCACACCTTGGCCAGAAAGGAAATGAAAGGTGCAGGGATATGCATCAATTAGCCTTAAATGGATCCAGTACTGCCCGGGTGTATACCTTGTCCTTGCTGTCTGTGGGGCTTGATGGTGGGCATCT
+
I(?8<94I(6<;1I'I(I.'H'9I9+&7:8I0'86I)I(I)59667:6H'995I*I(I(9749<:I(7;7I(;83=;E&I*:=I'39I)G'F'>:54:2I(?5I'55;I0';;7<;I2(69G'93;I':5;697:5<;3I)I/'8G'57I(;I1(G'28&664:3766:I'I(7H'4=88I*584498:6I)465:7>::6:I(7G'I(9I(49I)439I(838F'I'=I'9I)5:&768I(522:G'I(;4I(<545;?I'I(I(H'<3I.'H'I2(94I.&I)5<<;I1(:;;6763;;I(F&97I(I'I2(5I(58I)7276724I2(I1'9;6785I'I(37G'H'445<??656I=,'6I*7<3G'<I.'36;9:
@simulated.18
GACCTCAGCTAACGAGCCTTGGGATGTTCGCGCCAGTAACCCGCCAATTGGACCTGTCTGTTATTCACAGTCAAGTTGGGAATCCCTGTGGTACGCTGATAAAGAAGTGACTTACGTCCAATTCCGATCCCGTATCCAAAGAGTCTCACCGGAACTTGGGCAGCTGTTTTAAAGTCCGAGCTGTGTGGCGGGGTTACTGTCAGGCAGGACCTCTGTCTAAGTCATTACTTACCCGCGCGACGCAGTCAATTACTCATGCATTTGGATAAAGCAATATAGGCATGAAAGTCTCGCATACATTACCGGCACGATCATTTTTTCTCGTGACCATTCAGCTGATTGAAGTTCTCGCACACTCCGAATTCCATGTTGTCACCGGGAGAGACG
+
75I)=78::5G':854I(I)I-&467I(8<66I*5:7H'I1(3I(I(I)I'9I(4>78<7H'8I*446565;H'2I(I/'I(;I.'39;I(566:8;8;5I0'7I'69:49G'A447H'I(I(I(776I1(:287I'I/'687757:8I)F'G'6I)I1(669858I<,&I-&36I)7=364975:I(9I7*&I,3@89;6:H'1:I(7I(:853<::F&9:68I(88I(=I/'46757:<565:79G'I(=6693856;I0'I)67I4)70I(55/6I(6;76I0'8:7689:79764I)8I'I(3465;979II9.)&9478954I)AI'788<494H'5G':I(:6;5267888I(7I'I,H';4:H'?;6;I)I1(89?6537
@simulated.19
CGGGAGGATGGTGTTATTTTGTCTACGGTCTACCACTTGATCTAGAAGCTCCGCCTTTTGCGGACCTCAGGTTTAAAAGCTGCGGAAGCTAACGCTCGTAATCGGATGATTAACCACAAACACCTTGGGTTGCCTACCCGCAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAATTCGGAGTAGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATG
+
5I.'7G':8I(57G'7I8*&87746:G'6477F';<I(>:<;715I'455I(7G'I>,'5?I'4I)1:9I'I-&I=,'37899I)I';53I(174:887F'69H'=;9:H'I'F&6:I0'76I)I,I0'I*8I(95I2(5;99:783<I-&9:I5)H'=I/'87I'8970949I*<I(886:I,:8I'H'=<8I(9949?6=5:88<6:487:97:I5)I(8876I(4<7H'I+I(4I'779)4555676I(<I'<I(:699<87I(5I(8779787II7-(%:7;7:7<8I(I(6I'84;3788:596;I1(::<;E&58=6G':8I,<6F&I0':5563?79<I(I'19743874;;8:;I.':I)85H'<6
@simulated.20
ACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTACCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGTGGTGAAAAACACGTGGAGCTCGCGTTCATTACGCTGAACAGTAGTCATTCCACTAACGGTATCATGGAATAATACTATTGCGAGCTCTTGAAACATTACAAAGGCATGTCCATGCCCAGTTAACCCACCAGTACCAGGTATCCTGCTGCGAATGGTCACTAGATCAGCCGTAAGGTGCACTCCAGAGTGTTCATTCTCTAGTCTGCTGACTACCAGTATTGCGACGTTTCTGGCATGTTCGAGGCAGAATCTTCCCCAGCTTAGATTAGGTTACCGCCGCTTTCAAACTCATTTGT
+
8549I1(91I/'6I0'I'H':G'4I(9@585;7<I,&79:6<:9I=,'7&I*4I'5=6I3(254<924647I)66H'75=725:H'7>8I.&78672I)3I'8I,?I(65II3*&>666;I(>8:8;682I*4:I(68;589I(.74585485F'I(155G'4I(68964@I'I(8I'27575I)575=4:44I(6I0';8I(45I.&I,>5;59I(7>4I.'6:I(I)I/'<I(;=76I(;I)587I(7978<54I(2G'955:<:78:459I)85I*H'<96;8;I)52:7=6I)6<I(467956876668;824:I(94<5G'=::856I2(>4I'4694I):48I(<::I)13I(I=,'585I*576I(6F'I)7G'9I(;;I0'6I.&95:9I/';4
@simulated.21
CGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGCTAACTTGGTTTTATAGCGGTTCTCCGAAAAGAGCAAACTATTCCGAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCACGTTCTTTTAATAGCGGGGTGCCAACCTTCCCTAGAAACGTGGATTAATCGGGCCTCTGGTACCGTCAGTTCTCAATAGCGACACGAACACT
+
;5A<8I(59I'I(I2(-75I9*&687847I'I1(7H':I(I'=:6G'7I0';I(7884659:F'9I':I2(9889I(7>77I(I/'5;I2(8I(6I'9::<=53I2(8II5,'I(96I;+&=6:96I(68;83776;=<8;494<I'698:I-&I2(I(;99:879I(;6896:I(H':9I.'978<885G'4:::7I+1H'I(I8*&78559I(G'96I)4I9+&8@5=I.&66/F'H'77I'<:56H'I(5I?-'4I(I'9I(85>986788<5H'15I/'=7I(7F'7H'I';5;85G'877I>,'I'8I(86:I(I:+&9;7I-&<*8I(6IB.(H'8<-9I:+&43I)I*I(I'I.&;'7I-&5:6I);I(I(==I-&G'9:7I';7I';5886I':2:I)6556:486&5I'7466
@simulated.22
CGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCAGTAGGGGGGCTTTCTTTTCACTCAGAAAGTCCGGCAAAGACTACGTAAGAGCTGCCAATACCCGTTCGGATTCAATGCAGGAGCTCGCGTAAGGAATTATTTTATACCCGATTTTAAGGGAGCATATGGATCACCCTCGGGAACATTTCAAGTGGCAACGAACGACGCTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTGAGCAGTGACCGAAGGTAGGAAGCGACACACAATGCCATGCAATATAATTAGATGCCTGCC
+
2<=665767693I)I0'374I(777I:+&8II1)&4799H'76;I*8I(65;85:3I'7I0'98767=I(:2<;9799=9233:7I0';58I(38I'I(9<4875;865&4:II9.(%7I1(8I8*&;=73667I0'&4I'I(4I1'36995:67G':98:8:I(I*:;I/'6H':I)9I)9I(7843I(589578466I(I(I)I'9I:+&377I0':;I<,'I(I/'9875;66I'<754I.'75I.&I)<7I.&5I(35I*5H';4F&586617<5<8;:5I(768I(I(67I*494=85I(839789<<877I(2::<I(;382666<57G'9I(H'05I(I(76:797:85I'=6I(:5>:G'873F'H'6:787I(;;I'
@simulated.23
CGTCGTTCGTTGCCACTTGAAATGTTCCCGAGGGTGATCCATATGCTCCCTTAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCGAACGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAGCCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTACACCATGTTTCCTAGCTACAGACGAAGCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCA
+
79895I(=9I(<I)94G':I3(54I(I3(2;I-&6729G'0<5;6<5I2(I*I6)9<I0'676I>,':I(I(G'I)4::8788:7G'7467I*9I(5D2I)6I,?7I(I'<97;87I'<965:594I/'7I)H'6I.&9:44667I>,'4I,0II:.)&56866:48>48<G'I(<;I(88:I1(6:5<9953844:>66I(=996:7I-&5G'68:7347F'8I)889I'=535II5+'8I8*&;'86I'873I.&I(586:89;1?366I)9I6)I1(:88<999I'8876F&67I-&989I-&546<<785;84@68:5>67I(:89I'42:I)@6H'9I.'5:6675I'69863787<3:97:I.&4;>G'95;7449I2(8<5314I/'25747
@simulated.24
CGTTGTATTCCACCCGAGACCTTGTCCCGTTGCCACAGTATGATCGAGAATGACTAACTGGGTCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAGATCAGGTGTACCTGGAGTAGAAAAATAGGATCTCAAGCACTATGATCAGGTGATATTTGCTAATAACCCAATGTCGCCCCTCCATGAAGCCGCGCACCAGCTCCCTACGAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGG
+
85I(847I)I';I6)7469I(H':5I3('I'5F'57697=49585::6I+99>5<I(37I0'&I+I)6><I?-'4889I)9I(I(F&9I)625I'9;75I(E&885:760;::8I)I'338I(I1(7F&663E&3<67;I)56I'G'<99I)2:;I(5886:I(;I(>I(3?6G'7;;I(681>6:;3I'87=5I:+&=9I(857706=2I'<I':I0'I/'5768:I)8/67I*8I(;<6;5II2*&=7H'5:7:1I'757571599675I'91769I0'859F'4H'I.&I'3::69I9*&9I(877G';F':93:7I(968<I2(9:8'I(9I0'386I(5F'6844=6658959I(8I/'I)777I.&G'57I):7I(I)G'I1(
@simulated.25
ATGAAAGGTGCAGGGACTATGCATCAATTAGCCTTAAATGGATCCAGTACTGCCCGGGTGTATACCTTGTCCTTGCTGTCTGTGGGGCTTGATGGTGGGCATCTCGCACTCACACAAGGCTACGAGGCATGGCGGATATTTTGACAGCGTTCATCTGGGTATGACGCACCTAGTAGTGAATAGAGGCTCTCCACAGGGTACCCGGTCGAACATGGGCTAATAACTATGTTAAAATAGGATGGCTAGCATGCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCATACCCATTTCCTATGATCTCTAACGTTGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCCATCCGAT
+
649I.&I)=7<<I1'5(699>=96;I'I';7I)G'I/'=I(78G'6667:3=I3(I-&9:8884I'E&;4H'I)6;689:876I:+&<E&475I)=I4)866899<6866:<7;:F'I(9887:<I,664I(9I(:97I8*&;6<768:I(72566I/'9;869<=46I)547::;79H':879I*965;I)969I.'77I2(G'24;I(69>I0'81I(9I(8;<93I'I<,'4<I'=8I)D'85776577I(9G'35I9+&5:6:48676256F&6=:I(I(6I)769I(5;6I)5;:;I1(889I(3I(7:9<4:456795858796:98I(I)::94I-&8I3(I(<777572:97I(78I'6755I)7I(787I.'I0'5H'I)77I'88I-&G'7I.&9;I'>77
@simulated.26
CCGGCGTCCCTAGTAGGATTTGCACAGACTCAATCTAGTCACGTCCGCTAGCATCGGAGAGGCGACCATAAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCGTGACTACCCCAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTCTCAGACCTTCTCTGTTCATAAAACTTACGCATGATGCACCCCGGATAGCCCTTCAGGGTAGGTGTCTAGATATGCGAGCGACCGACGACTTATAGTCAGCTACGGTCCCTCAATGGCCCTGATGCCTTTAATCCCTAGCGGCGGGTGTAGCGGGTCGACTAGGCACCAGGTCAGCAACCTGACTAGAAGCGGGGTCAAGC
+
I(I(765I.&:90;CI'8I/':6:47:7344I):2622976463I'8:7;8<954I(8;5I(:74F'77I/'7I(37G'76:;7>:96=7I'9684I(33G'=4759I(G'53;7I'I'6I/'I3(G'7266I,679387>I<,&:6428678;59775;8:I1':85@:775=85I(3/;59499:826889I(44689669;6G'8I(I)84I(4;7G'7I(:I(I-&C87::<:I(F&81>57I(7:<I<,';I(188;59:88?;5I:+&I):66=I3(I)76I1(56I);@72:<982977:6A7>7<I'5;6:;7I(478:842<768;I(;I/':5I)4I(I1(86677I(I0'G'4I/'1::7I(9I.&7<6786I.&6;99536I(;6I'5G'68789H'I':466=:<I)98I=,'8;I(65
@simulated.27
CCAGGTCAGCAACCTGACTAGAAGCGGGGTCAAGCGTGTTTAGGCTGGGCAGTTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAAACCATGCTAGTAGCATGAAGCCGACGTATACAGACTAGCTAGGGGCCTACGCGCATTAGCCGAATGCCCCGATAGCCTCGCCTGACAGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAAACCGTTATCACTAGGTGTTATGTTCTCCAATGAGTTAACGGCAAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCG
+
I(6I(<9087I(I'4674277I(;6I<,'44I(:84:6I,&7I(2;I0'65&I(94<85<:75<7::I'I/'1::6954I)79I(677;:889IB.(I(<7448:59+7=66?H'=I'843788631758:26>:55I;+&I(92859699G'37I(8H'67I7*&567'7H'7@7I)8779746I(17I)6I*I(89F'6529I1(<6I(I(7I=,'I(8I(89596':G'5;I);5:I(72E&H'7:77I(I,8I(>I.'I3(:I-&6I(8I'=<:F&I8*&58:27:8:99F'6I(I'8;I'I2(4585468I,&68I)76I':I/'7I(<5I'I(7:94589887565I)72595:8>>I;+&7I';E&;2E&5I3(844868I):I(5>89:9I)?732I'H'8I.&:H'I)I0'=
@simulated.28
GTAGAAACTTGATTCTTGTTTTGTCTGTCGCAACATGTAGACAGACTTAACTAATCCCTCCTGCCTCGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACGTCGGCTTCATGCACTAGCATGGTTTTATAGACATCCAGCCACAGTGCAAACCGATAGTACGCAGCTAATGCCCAGCCTAAACACGCTTGACCCCGCTTCTAGTCAGGTTGCTGACCTGGTGCCTAGTCGACCCGCTACACCCGCCGCTAGGGATTAAAGGCATCAGGGCCATT
+
;<8:I/'8I(;8E&9I(5I<,'8;>@7:686I(73>67785:1847G'I'28H':I0'5D&98E&98I+78332:5I/'I(69I)I);I(7=688;8699I:+&I*933G'9I(3I3(7I1(I.&=I(7I-&I(;766I'6:8I(;<=I)74H'7;8646I)4I)I:+&5I(I(44I.'/9:<H'48I'I)7I(31I(387:;25I(878G'6275I=,';:I':I(63I(365769/5I(I=,'4669567:70783369472I(7I+4867987757;8;I(I?-'646<5967I(93I(79777:9I3(I(:86(99<:8883:8I(9>I1(56I(9I.&=;/64H'6;I<,&95G'5>666:;H'G'85753I(3G'73I(::46461I/'759;7:I3(6H'=89<I.&:I'I1'I(<;:99I2(H'6E&
@simulated.29
AATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAGCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACACGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGAGTGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCTAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTACAGTAGACCTGTGCTCGGA
+
F'I'I*I':961:2755I)3::7H';I(8I(5I)7I.&54I*I(784788H'<89;6:8:I.&2I(I';I2(4573658I;+&9I,4II6,(<6<479777:67I)I)7:I'6;6I3(5973;94+:63<8:64I(88<:59I0'8I(88477=8H'9I)638H'3978IH0)%7I8*&896I(657I0'I(47::58@48;5AI(7I8*&I0'65:3<78G'8894I(5;I.&A3:I1(79;6<653;6&5:763:867I(1<>I(747I'<8I)6I2(97::7;I(8(77=7;687;;769I/'7:<I(9987655I.&6787<6I1(96;59I/'8I'84I<,':I(I1'6864:9I';74897296&3:87585I(1?:816;I(:
@simulated.30
GTTAAAGCAAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCGATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCACTCGCATGGAGTAATGTTGAGGGTCCCCCCATTTTCCACTATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACCAGCATACCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATTGCAAGGTTTGATGGGTTGGTCTATCTCGACATCCCATCTTACCAA
+
7I(I0'9:I.&:88I2(I)9I'IG0)%53867G':I(H':;I(99I(64I(8798;I0'29I(59:7:;:8>88I(:I/'9=7I'9IB.(7:6:1I(9:I(H'66I(I'939::9;I(63:I)I)9455565877*84I'9H'?712I(<75I(5I-&I(I'57<9I):I(56946I)9<7:5I';779I'::67;:8I/'6I.&7*44>668I(785G'<6H'33I.&9II8-(%9IB.(I*77'476876I(665I0'87H'463I)59<<8I(84I(7167H':829<8<6;I':798<I'574G'97I'I);I/'<I)774769II7-(;6788::9;:I(5866I,&:79I)0I'5658H'5277I;+&:I'I.'737I)788I)I(95I(I(I1'675I0'I)I(47-74:2556::8I0'5:;E&3I(G'
@simulated.31
GGATCGTGTCGCACTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGTGAATGACAAGAGATAGAAAGGGGCTTCGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCATAGGGGGGCTTTCTTTTCACTCAGAAATCCGGCAAAGACTACGTAAGAGCTGCCAATACCCGTTCGGATTCAATGCAGGAGCTCGCGTAAGGAATTATTTTATACCCGATTTTAAGGGAGCATATGGATCACCCTCGGGAACATTTCAAGTGGCAACGAACGACGCTCATGCGTTAGTCCGGCGTTATACTATAATACTACTATATCCGTCTGGTGAGCAGTGACC
+
I(0;571398<69146G'59634>I.&6I(72I)976H'486I)399<776365757::;:18I.'367I,47I'8<36I(:5:7:;7I2(I9+&5I)5:48556718:;F'I1':58G'648I:+&7II1*&48;2I'38:E&9I'652:780I(4I2(7;5278I(;2;=80958:25=77I-&7>4G'44I)H'=:33069>48;5II=0*&7I-&9I;+&9654::8I/';I'H'6I/'71?68989H':459A6I'I(;4I-&1G'9I(2G';I'8643I)15373;676I(I*I'H'4I@-'359I.&<:I=,'I(I-&<>8868:I)8:66I0'<8I3(I(65I/'5I(89I)6I(;6I(<858387<:;6:6G'567H'G':9I(4?16&67I)<4;9<66984:I(9:27I(;;46328174I(
@simulated.32
TTGCGGGAACAATCTTTCGAGCAGCGCGAGCTGTTACAGCATTTCGTGAGTGCTATTCGATGAGCCCTGCATGTACGGTAGGTTCTGGTAACTCATCCCGTTACGTGAATACAATGAGGTCGACGATCAATTCTCTGCGGTACGTGGGCAGTTTACATTATACAGATTGTATTACGGAAGCTGTTCCTCTAGATCTTATTAAATAATAGCCAACAAACCGTTGTCGGTTCCGCGCTTGAAATGCGCGCGCCTGCGTACGATCATGTGCATGCCCGAATAGCCGACCCGGTTCATGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGAGGAACATCTATGCCGCCGACGGGCC
+
I(39I/'I'6I(67I3((5:<:8:73A8453:9I)457562I.&628589><6(5I(66579.3I.&56=;554<8I(94I(I)85I(<H'69677I1':H'99275I'=81I(68;I'9;:;:197;I(G'23;3D9I(3;665I.':93I/'8<6I(=4:=96:I(558F'54I'I(9:9;G'I(67946=66I(7G'I5)5I(887I)I)9I1(I(8I(5A7I(G'G'662;I(7I0'646<7=67I(9>3556;9585<:45197;3I0'2I'651H'76I1(F'I(>A7?892=85I'4<75I*67I'4=I(3I(65H'I)9I(6E&7452;8I(I):356377:G'8I)8:4I/'H'
@simulated.33
GTACAATACGTGCATGGTTTGAGTATCATAGGATGACATGTGGGCTACTATCTTCCATAAGGAAAAACGCGGGCACGATTTGGTACGACGAGCAGACGACCAACTTCCTCTCACTTTGTACTGCCTGTGCGGGCCGGCAAATCCAAGTAGTTAGAGATGGCGGCTGTAGAAACTTGATTCTTGTTTTGTCTGTACGCAACATGTAGACAGACTTAACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACGTCGGCTT
+
59:6H'8<7<>=877I(I/'67%:6196;3H'93=8<74<7I1(4(956523H'G'63I'I)II2*&7>;I4):::85I.'I'7:553545:8766=68I(I(9G'G'65;7;8I0'36?87:G':<58:I.&I'I(9I0'7I(I(5689I*9:57:3I(8G'9933;5I0'8H':6I(5G'5IB.(:9690:'393I*9<6:17:778595I(H'<8I(;I.&=I(3:F'77I.&49759:5I.'I(8:F'G'6I(47:7793755I:+&I'<;:I*1H'4I/'4I/'I,&8I(5I.&F'77>5I):9;I'72:I(7:H':5629;I':I*I@-'8H'H'68I/'8962I':5E&I(6G'59I';73?585I)9>:G'896:I6*7;H'3I'63H'<<7:7559I(I?-'89866352785;9;5977?F'7H'
@simulated.34
GGATCCTATCGGATGGGACCTTTAGAATGTTCCGTTTCCCGTCAACTTAGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCGTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGTAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCATACCCAGATGAACGCTGTCAAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTTAAGGCTAATTGATGACATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTC
+
I'35G'6;;6I)<3I1'9I)I.&53I(6:I(I)<I2(I-&7:5H'9I(&>82:I(3:E&8969;=5756I(I-&6I-&2;<4I(G'589077:6:994;89:7:6;7G'(>I)998I.':358G'946I(634I(7I(G';87H'755;7979;<78I9*&5<I)4I)';94>:;7>I(G'96H'66I9*&I)9:544I):I)86I0'376I(33<I)I0'73I.&8:7I'76:9I)967:I(4;;;8693H':=75825:7I0'887:7I'76888::I:+&759I(7E&434I-&<68679H'I(7:774<846;888789I2(8I(955I'6I9+&49467;8:9I(I(3;H'I(<:<7A7I0'I/'.8;9467I)7<I(4I0'F'I(48I(I(7;35%68775I4):=57I(I-&43I0'I(I-&6;I(I'E&I(598754I)8=
@simulated.35
GGTCTTTCGGTCCGCTCTTAGGCAGAAGTTCGTAAAACCCAAGTGCGTTTTGCGACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGCTGCTACTGCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCAGTAGCAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAG
+
I+'5I-&=I*4I(6::=I(=H':59I(:I)=35I;+&I2(I(;:659I:+&752<:<;I1(2:5;8973::8;7E&8I'8;7I)4G'956I/'7I)5H'5;I*945H'I+I(8;:I;+&I(9:I0'I(I0'I)5I(I/'I0'I(I/'3>3;64;87I,8H'8:I(76I(I(5;6I)I/'99:3:62I6);5:I*:685492693AI)57I0'45:I*8466:3<I(I)077:7;H':16=9:857I(7I'I(6F'II1*&59I(<;&<65:G'I0':I(I2(;:=I(88<6:I(87I'6I0'I.&I(3<:74657;I(4I)26I(85?785879766I<,'77I*I)I(I(G'785:;8755I'5I'I(89I)7H':86I(I(95H'46
@simulated.36
CCCATTTCCTATGATCTCTAACGTTGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCATCCGATAGGATCCAGAGCGTGTGGATTATGAGTTCGCACCTGTGACGGTAAATTTTTGTGGTGAGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAAGACCCTGCTAGGCATCTGCTAACCTAGATTGAATACGATACTGAATGGGATAATATCGTATTAGCGAGAAACTAAAGTAAGGGCCCGCAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAACGACGCCCACGGTGTAACGCGTATTACCACCGGTGTACTGTGCTCTCCTATATGGTAGCGACCGCG
+
I0'7I/'I(34;5954583I)6;I(82=4I(=I)91?I3(I.'5H'I)75H'87I0'H'4I,78I(1488I)<4I(884668763I(4I':;29;E&8:56I)87867:H'8I0'II4+'5:I(65973;;45=94;I*I<,&87I)8;I(I2(9H'I(75:89I'9I'7H'997D&86I/'76>78I'47955872I(I'6745I)6I)397+686186I(;I-&59I(65>65;8H'887759I.&5:I-&8%I*I3(I.'8:4I(66686;I'I(4I(9:I*97>I'78I(7I(3H'I)75I.'I(I)(3697I0'45F'596I)688989I'4I+9I(I(3=96&:8=8877:F&6::<8F&396;;9H'52;
@simulated.37
AAGATTCATAGCAAGGGCTTAAATGATTACGTGTAAGTAATGGGCCCAAGTACACGTATTGTTACAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGTCTCATGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGATTGCATGTGCGTTGCACAACCACTACGAAAGGAAGCCTCGAGATTCATGGGCCCGTCGGCGGCATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAACGATCT
+
I)/6H'169577I(I3(7H'I-&8:3I':7'89:H'59H':I-&I.&I)<94::88;:I)5I('9<I(9=::>7596>78I:+&1=I)I)I'I'I(;76877:86H':I(I)<5I(<I(86>I'E&58I(5I/'9<:86I(:85::87:98I/'4G'8H'8&:5594782<5I(675I,&87:I(7753;7I*:88I)I)7G'078I(<979A78:9I'46:9I(I(88<=8)I0'I(I'2G'774559I(:6:I5)I-&156I(:I(4:75<;89I'I'706;<<I)8H'3I(I)76I(<I(69H'<:I'9887I(08464>5;57F'H'I/'98G'48:G'5I1'7936635824=8784;726;I(8::68789I-&6I):8:6I+I'I)7;9I(9F'I0'2I(I(<97I)4I2(I(8I(&57752
@simulated.38
AGTGGCAACGAACGACGCTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTGAGCAGTGACCGAAGGTAGGAAGCGACACACAATGCCATGCTAATATAATTAGATGCCTGCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGAGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGGAAGATTCTGCCTCGAACATGCCAGAAACGTCGCAATACTGGTAGTCAGCAGACTAGAGAATGAACACTCTGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACCTGGTACTGGTGGGTTAACTGGGCATGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCATGATACCGTTAGTGGAAT
+
9;;E&:I'65H';7;67:>;59727I'597I(I(48H'7>5:4=I+<:=7?768:38I(57:7I(:57957668<I):I(I);5I(I(65<476765I(9<I)753;&I(74;G'I';658:H'96H'II4+':3:74;I(865I)4:77;I)8847I)9G'I(;557;I0':77>I-&4I0'92I'8I'6H'I'?I'789I'68;I>,'I(:4I(148I(966I)<744H'8:I0'7689<5H':=67I*67;;;559784694571I(57I(4:87;9H'65:587I'H'86I(:=64:;868488I(8I'48:5698I(185I(6I(1:64I':I-&H'I(2:I0'674I(:6:93I/'I0'67I';7I/';I(7:65=352I)37<8;I'4H'H':87749I'5I)>64H'I(8
@simulated.39
TCATCCGATTACGAGCGTTAGCTTCCGCAGCTTTTAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCTCAGGCCGGAATCACAAACGAATACCAATTAATCGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGACTAAACTTGGTTTTATAGCGGTTCTCCGAAAA
+
58;9I'56I(79>9;03I'86<I+I'A65<7I;+&I,I)698I'8I)69I9+&I(9I';89I(7755983I(30F&:989I(6<726:I9*&7G'53I';<E&9I.':=;8383I(I(I)I(4284I.&:6I'48H'I)I)I(49<978I)63H'I'I.&9:<I>,'444869I(I2(5I(8I(G'876I':I/'5I(9;741879H':I(4I.&:97<I(:;47DI5)::I3(9I)3I)46781:9I/'8IH0)%I)87I<,':9392I(9:8875<7529395687G'08:7I/'I-&G'26==4<4I(774875I(I(92I1(786:6?6F&:<5%:;I.&9I(I)I;+&;494<G'I'74I(<I<+&
@simulated.40
CGCAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAAATTCGGAGTGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACAGTAAACCCCGCCACACGAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTTATCAGCGTACCACAGGGATTCCCAACTTG
+
50;98=6259I/'A:I0'I'5I.'28H'8:75757I*5I)88:8I.&76I)I(=5;I(=889:6::=8783378:55::I/'I'5485I'=5;I*I/'I)7I(525267<=96I)<G'8I'6;<69:9I'6I'5855915II7-(%88;78959I'I(:E&379::8889735I/'7478I(4896H'96I1'80I*I/'496576697I(I(5855;5725:93:I/'8I'79H'5895I'9748438I(9I)57F'427:3;5I-&I9+&8I(7978)57713F'66I-&IA-'665578I/'I)4I(I'H'7584;=27I1'G'9977I/'754G'E&I'I(3846F&6<55<H'8I1(>52::7<=9H'7<5I-&5I(I0'I(9I'5
@simulated.41
AATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTAGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTTCGGAAGCGTTTCGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACTGTCTTTCTCCCACTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCTAGTAAGGATTTGCAC
+
I(:769I(:F'G'I(I(I9*&575>I(67I0'3<8;;89I(626F&927853I?-'68488I(I-&789H'6F'<G'<I1(999<8879II3*&7I(I(5;97I0'I/';2697:5:4<I(I)I.'=+5814<364I.&I(297I(88I)68I0'F&;0:64=9I(;49I(4:9690H':8=958826I*:3I(6I(I(I'75I8*&:/;9898I'77I'IC.(975H'82I.&3887I.&3I(G'726I0'%612479H'37278I(9I(I)=879678:I-&:6<64I.'948655=H'387994:I3(5:I/'7A8757677:I'7655<2:6I*69I*:7I)865I)758II7-(%I(925I+75=8F'I(7I1(<8<7
@simulated.42
CGTATGTCTAATGTGAGTCTCGAAAGTGTACCCAAGAGGCTAGGATTCCCACTGTAACACAGCCACACGGTTATGGACGCTGAGCCTAACATTAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTGAAGTATGCTAGATAATTGGCCCGGTCGCGCCATAAGAAGCGGGACGCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCGACCTATTGCTGAGGAGAGGTGCGTAACCGCAGTCTTCCAATATCCCGTGGTCATAGTATGCAGCTGTGGTACATTCTGGT
+
<47448758I(:62592?5:;7I6*3797DI2(I(85I(969I)5I(I/'8(857I)5<679I*66=5G'I(:2I(8:<6:::<F'7I(87G'269987I4)I(44F';8777I(6I(I(768343H'7:968I*56I)<4:689+<879I(I'H'I/'I(87685H'59H'6F&39I0'947I)9I):>45681847:I)439I1(G'9699I(968I(H'7:I/'759I(8876;98I)748E&878;864417683:9;77<I(65I(8=;I)4736014;84I(5<77G'I(6/E&=977%4I)88G'349:7I(431H'63847H'I(656534F'E&I*65<I.&28I(77D8:8;7479;:7487I)9786H'85G'9
@simulated.43
TGGGACCTTTAGAATGTTCCGTTTCCGTCAACTTGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCGATGTTCGACGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCGATACCCAGATGTAACGCTGTCAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTA
+
7I/'=I(I.'4;I'59I*I'6I/'I,84:I(5H'5539H'<2I(86:777=:79I)I3(6I2(8579I(I';5511784:494859@<<571I(6H'976I-&>884H'377I*89:H'7I(I(;:6I)8;932?5656:=I;+&45I(7I(88785:70I)I)>6I'76I;+&I)99;70I(7I(@6I/')759I(66ABI0'6:I/':77G'::18I'7@76H'64774749I'5:9659&683I/'68876)I(0:58845I6)69<E&5I)5;7I1(868357G'I(6<757629747:55:5I0'3E&;56I'9I<,'9?<8:7737I)F'7:I)I);49594I0'I1(41136
@simulated.44
CCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGTAGCCGGTCACCGGCCCGGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCTACAAAATCATCTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCGATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCTAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACTGTCTTTCTCCCACCT
+
I(7<I(I(3:I)H'3I(9;672534>I*9I'6I'H'455I'I(9;:39I(II7-(598I(I();4I)I(I0'I*28I'79=6I0'6736I'<5539;I)5=I)8G'6,<3I*:I)DI)I)I:+&877;I(37I.'::46780I'315I(8884%3:I:+&3=68:DI.&<79I)-I(7I(7I0'5:6877<7IG/)%>G'E&7<>:I.'I0':3773::645I(G'I1(::3894846I3(I(349G';8I)87I-&I*87>67:;G':7=I)&7:<77<I';2;8::866I);3I(/I'H'I)67I:+&=846688I'99I(I:+&787I*%<?I/'7463I/'4I(I(::3I1(952465H';5885I(4I(I'9738884<I1(83768I0'66>7:49I'4778848I,&84I2(:I'5
@simulated.45
ATACGCAGTAACTTGCCAACCTCGTCTGAATGGGAAAAAGCTAGGATCACCAGGCGGTTGCTTTGCGCACGGCAACTACGCGTTCATACTATCAGTTAGATCGATTTCAGTGTGAACGCAATGACTCATACGCTCCAATATTATGACCGCTACTATAACACGGTCGGCTGTTAATTCGAACGTTTTCATGGCTCCGTGTTTCAGCGGCCCTTGTCGACTACGGAGCGCTCAAGACCAAACCTGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGAGTAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGATCGGGTGTAGTAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTG
+
669888:74F&7I(:I(I'I'9;5299:I)6I4)II4+'774:I*43<>I'<H'@I(F'.8I,&36474;G':I'6944468I'4=8688>8698H'6670669I-&:57:83<I(;7:I(6;:8946692968I)G'6:I):5;5H'<4988246I'9<=I':4I+448I)I(I(94I*6=I:+&8>9I)6<I(6=7I3(6865I(I-&I'493974;?8I'4689>:3I'86I(I/'I*5I,781I(75479=7I'I(I'28F&II1*&47=9I'45I(I.&I)F'3'53756I1(3;9;I*=8:1;43I(=:47;986<64296:7I(:778;9I4)F&6I:+&:4I*4I.&75;68I-&5137'69I-&7873849I':73I-&:9<58<48;::746F'25;4
@simulated.46
CGATAAGTCCAGTCGCTGGCTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGTCTGATACCGCTACTTGGTTAGGGATCTTATGTCTTCAATTTGATCTGTGCTTTCCACGGGACAACCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCGCTATTAAAAGAACTGGGTGATTTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATTTCATTGACATAGATGAGGCTTAACTTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTCGGAGAACCGCTATAAAACCAAGTTTAGCTGAATGACATGAAAGACCGGTATGTGAACAGTCTACCTTTCCCGACTAACA
+
A179G'8%I);696564I'8F'4:8:77:8I(866=76I0'0I/'8F'8G'F'I(849I'4I(;:43668'275<38I'867;2I'H'I(5I2(;50I(=9439F'7G'I3(87<5288;8I0'I(93I.'96I(I5)G'97;86;767;I(I(I(I)98:?6784:7:6I'7@7I0'7;7<4::=I+II1)&5<;95=793G'5850:2727I(579I'96469I(86F'95;I(I/':9I(I(8I(887I/'58I0'I'G'I(I(6<I7*9384I(IF/)7E&9:I6)8:7I<+&I(:87I)9I(I;+&825I(8;546I(I(<F'8I(:8I.':7F'68777860=79H'1I*I(9I9+&6I'I)3:95I(76I(I'653I.'66:;I<,&9I):;I(I(84752I9+&I(I(8I2(<6;=7E&6897767I0'23I'I(5965::I(;9::797H'I-&I0'=437I(66
@simulated.47
AGTTTCGGCACAGGTGCCGCATCAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAAGCGCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCAAACCTCCTCATGGAGCTAAGCTACGAGACCCCCTGCGCCTATCTTCGCAAAATCCGTGTTCTAAGCGTTAAAGCAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAAGTGTCTGCAAGTATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGA
+
53I0'<I(6;69I'86H'<::7<I1':46347I):I):0956I/'I)539I(7@5:89I4);68CI(::4@:I(7697I1(7893F&99I(79IE/(I4)I'5I'5767H'33:9I(89:7)<786II1*&555>I(8629I(827I<,&7I+;<7I(54G'C69G'I0'49I,867I.'I+8I(II3*&56::9H'9I(I(97I'9;I(87I(54689I/'65I'9?<2525:6:7H';I0'895I(2I>,'4:555I(:7I)I(69I)F&08<8:9=6I((4=6I'I):69798>794?:I'8H'978:I(838I(3I.'I(I(/<57I*:I)B6:89I'99943I(4576I'6914881I.&7I.'05777;5H'=75I(68I(:3I.&8II<0*&9I;+&I'8483?<43H'51
@simulated.48
TGGAAGCGAAGTTGCACCCATACCAGCCTCACGGCCTGATGAATTCAGAAAAAGCCCAGCTTTAGGGGTCGCCAGATCTTAGTGTCCGGCGGATATGCGAGAGTATTGGTACATCAGACTGCAAAGGACTGGCCAAGTCAATGGGTTATCTGGCTCATGCAATACGCAGTAACTTGCCAACCTCGTCTGAATGGAAAAAGCTAGGATCACCAGGCGGTTGCTTTGCGCACGGCAACGTACGCGTTCATACTATCAGTTAGATCGATTTCAGTGTGAACGCAATGACTCATACGCTCCAATATTATGACCGCTACTATAACTACGGTCGGCGTGTTAATTCGAACGTTTCATGGCTCCGTGTTCAGCGGCCCTTGTCGACTAC
+
6I)I(897I'6E&:=4I7*689I'4;E&4:<9G'I'78496I)I';76II4+'5I0'8<4I0'6I:+&5&5I(98758I)36657I(F';I(37777876:7;5:H'G'38=7>>1769463I/'F&:5:I(I(I(949I(9I.&I(7:68G':/4;55=I(:93>957<H'7G'9I)F'I(99::724I(=I,II0)&<978I(<819I(8I+:I)I(8:I/'5;9<97G'8I(6*:385>7I(5648636394?I(;5476:6I/'6478:;8G'9;=I(1597:89558275I)I(77I(9359I(<=<85:;4G':*57I(35I(5(;=I'I(G'3:I'16I5)445I(;8F'4:6I,859<I(I1(F'9478752<7
@simulated.49
AAACCCAAGTGCGTTTTGCGACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGTCTGCTACTCGCCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGAGTGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTC
+
I1(I0'I)727;<I>,'9:468:8I1'3464777349458I)9I).:6I(9I(078I.&5H'6I(5;I(6:>I)I(I'2:6I<,'I)78I/'I(I3(I)5I(I0'I/'I(I0'&37;866>6%6I/'5I(39I(99I(F'8:7I)I0'77;6588I>,'=78I';=9;7=96377G'88I1(:91I(55:59&92I*H'5:2884I(616;78723I(1I(I)8I)II1*&=9I(59667=I'I0'4I(I-&955I(68592H'39I':I0'I0'I(:99624<86I(7I*>8I):9;56936635;I8*&57F'I'E&E&I'8653<:76;I(2H'I'76I*>F'54;G'I(8=I(5I/'38;98H'5591;35545I0'7I(9H';5:9
@simulated.50
AACTGGGTGATTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATTTCATTGACATAGATGAGGTCTTAACTTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTCGGAGAACCGCTATAAAACCAAGTTTAGCTGAATGACATGAAAGACCGGTATGTGAACAGTCGTACCTTTCCCGACTAACATCGTGACTATGTGATAAGTATCAAAATCAACCCCCACCCAGCATGTAATGGTAAATCTTTAAGAGACCAGACGGGCAAGCCTCTCAGTGCCTAAAGAAGTCGGTTGCCTGGGCCGTCACACCCCGACTTTGGTTCATTGCTCGATTAATTGGTATTCGTTTGTGATTCCGGCCTGAGATCGGGAGGATGGTGTTATTTTGTCTACGGTCTACCACTTGATCTAGAAGCTCCGCCTTTTGCGGACCTCAGGT
+
I':5I-&7;7I6*I(845H'7I(I;+&732I*226;6I)I(9I(8I)57I.'56I(8985;793/36I*&9I(I)8I:+&7I(I(:<75I(45I)I(976I-&;7;7I;+&9E&65I)I'672;6I<,'I(I'7I0':9835I)2894884I-&98E&I(1766;0I(64758%7<I(I/'I-&7:75I(39<<9567898974695I'34>96I:+&<;I'II2*&:I-&:<5<:3<I(8I(4I1(;6I0'I)57:5I):8;:I1(8I(6I)585:23;9I(4I0'9I(<33I(I(8I(2I3(G'676675I<,'989I-&I(I,87I(:67528I'E&I(I(;9I(;?I3(8<86I(I'I(I(6::8:86I2(:I':8I(78I(9I@-'5:4898I(8953I(78I)56:74:8I'878I'6I'IB.(64I)6I(;:<I(9
@simulated.51
GGCTGTTAATTCGAACGTTTTCATGGCTCCGTGTTTCAGCGGCCCTTGTCGACTACGGAGCGCTCAAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGATCGGGTGTATAGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGTGAATGACAAGAGATAGAAAGGGGCTTCGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCT
+
H'7;4I'I(I'7;I+<3I;+&589H'63I(::4I/'=2:7I(I0'G'886979699H'6745588I(7<I'I/'I'8I0'688F'5::7=97H'I(I(86I(II2*&;827I)8;I)I/'I)I'58:676I/'918<I'658;286I'72;3958949336=87I(5=4855I.&I(;I>,'9<I(6I1(48<99I1'9;74>6I*9786/77I)649I-&875;<6:65:88<7I'47452=I-&3I)87I(189I(:=:H'5243548816369;57;<9I-&73<I,37H'4<60I(83<9427I0'I?-'4I(:947168;2975G'I/'89<I*879I;+&:II3*&786<I)1:5I(6I(79=745/I(9I0'963:99
@simulated.52
TTGACTGTGAATAACAGACAGGTCCAATTGGCGGGTTACTGGCGCGAACATCCCAAGGCTCGTTAGCTGAGGTCGGGCTCCACCAGAGAGAGTCGAGTTAAACGGGCCAACCTACTCGTCGTCGAGTGGTTTACAAGCATAACTTGGCACCCGCGGGGACTAGTCGCTCCTTTAAATGTCCAGCACCGGGATGTGTGCGCATTGAAGGACGTTAGGTGGCCTCTATTACGTCCATCGAGAATGCGTTCGCTTTAGTGACGTGATATAGTGCGGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAGTTTTTGACACATTCTACATCTACCTTGGCACATCCCGTTTCCCGGTGGGGTAGCTTCAATCGTCTGAGTGGGTAATGCCTTCGCACTGGTCAACTGTCGCGTT
+
I(6;<7758I)4H'7969<6F'2H'I'I(H'<I0'H';:9G'4545E&679I.'I'I(7:14G';78675E&95I/':9H'6I(7:339569759<3H'I.&8I/'I(I'I'6:38766456?5479I(I/'4>I(567:I)4I(I(::I4)78I9*&73886%;;:8I(I0'I/'859I(6878I(I-&8;5942:8:<0H'?I'I(.A3I'2I(9I)I(79:;I(94:&I)767<54H'76:7H'6>>I.&:77679043;3785;:8;II1*&I'2826;665I(5<42I(G'I(38I/'88=3H'34I(867>4I(9II2*&367<;6I'567437486I(I)I':89;;I/'6I.'I-&F'8I?-'458:H'4I(;;:9486877I/'5I)95G'H'9778<;I(06I'48<8:6<8F'
@simulated.53
GCGCGGGTAAGTAAGTGACTTAGACAGAGGTCCTGCCTGACAGTAAACCCCGCCACACAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTTATCAGCGTACCACAGGGATTCCCAACTTGACTGTGAATAACAGACAGGTCCAATTGGCGGGTTACTGGCGCGAACATCCAAGGCTCGTTAGCTGAGGTCGGCTCCACCAGTAGAGAGTCGAGTTAAACGGGCCAACCTACTCGTCGTCGAGTGGTTTACAAGCATAACTTGGCACCCGCGGGACTAGCGACTCCTTTAATGTCCAGCACCGGGATGTGTGCGCATTGAAGGACGTTAGGTGGCCTCTATT
+
7659I/'8I(=8I)&878;I':367877I)3H'57I(7496;64I/'I;+&8E&8448;8987H'5<I.'I;+&78;=95I1(I(8I(G'I(88<69>96I6)I);74=I/'55=I(I(I(H'7535G'2<655G'8I/':63575541I(=<8I1(4I(I0'I(>I(<7978;7I*7I(9>36>7I'4I(I(H'I';I.&I'767I'595<I(889I,I)I(7439H'35872:H'77I,;9G'7I(77'48;266::778F'I3(/I2(I(I(I)7697166:76677:8I(I/'8:G'878;I)9I(H':9I.&64I6):8<9553&57I(I0'I,789I'>4:3I(I1(77;9=476;9;I(9I(I*954H'7G'5I(I(6479I)
@simulated.54
TAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGATTGCATGTGCGTTGCACAACCACTACAAAGAAGTCCTCGAGATTCATGGGCCCGTCGGCGGCTATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCTTCCGTAATACAATCTGTATAATGTAAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTCATTGTATCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGGCTCACT
+
572G'I(81I(7I.'5797>I(58<69=43;:I/'6I(8I(5<7957G';5<3I(:<5I-&38:I';7868:I)788G'I)8I(674I(66<:6576>H'9584I)G'84883I/'CI)5'G'7786;;H'909I0'I-&789I'4I(9)5:4838;G'H'>.:532I*8I)9I(F'7>G'8I*57I(:3H'6:6;D56?73=6778F&I(I-&:=H'6<<I*7I.'5;3;57867689=8632:67H'9;:2844;I-&>I(87;8I(I'I)28:H'6I(I/':I(I(6=6I(5I/'I)9I(;5958::?I(I)2553I(I(;9I*26;I(9;:=92<I(67:I/'6:6I0'35699I(8H'69<3I(I(6;9A<476;I)647H'7:4C:5;6;I);I0'77922I(9I*55G'I(76I(5797;0<8;I1(86:6%6
@simulated.55
TCGTATTAGCGAGAAACTAAAGAAGGGCCCGCGAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAAGACGCCACGGTGTAACGCGTATTACCCACCGGTGTATGTGCTCTCCTATATGGTAGCGACCGCGCGGAGGAAAAGCCGGACTCCTGGAAGCGAAGTTGCACCCCATACCAGCCTCACGGCCTGATGAATCAGAAAAAGCCCAGCTTTAGGGGTGCCAGATCTTAGTGTCCGGCGGATATGCGAGAGTATTGGTACATCAGACTGCAAAGGACTGGCCAAGTCAATGGGTTATCTGGCTCATGCAATACGCAGTAACTTGCCAACCTCGTCTGAATGGGAAAAGCTAGGATCACCAGGCGGTTGCTTTGCGCACGGCAACTACGCGTTCATACTATCAGTTA
+
6;.38H':39878I0'59I.&3I'I.&I.&54';I(88=:58G'I)5I(<8I(:49H'=;I)7I)8I)I(62I/'I'I'887=I+48I'955I*98875:I(9I1(9G'I(5456;99:85=<I(47=:6F'5:;:7=E&764<I)6I'IB.(8I(I':6:I'DI)I(85;F';I)899I;+&786I)85G'>445I'I*<779:I'B767II0)&6I0'846I/':I9+&8:H'5;788E&794:7I'F'5H':5:5:98=6;9;6I(I(;35758435299;I0'H'777I(I(I*739I(3I0'I'8397I(25;;<5:G'/?@87677G'7I(:H'H'F'7:89588I*:I.'IE/(7738I(6:29I(9I)3I(I(8=I/':7794;I)7G'9767542I(4::55759348E&1
@simulated.56
TCTAGACTCTTATAAATAATAGCCAACAAACCGTTGTCGGTTCCGCGCTTGAAATGCGCGCGCCTGCGTACGTATCATGTGCATGCCCGAATAGCCGACCCGGTTCATGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGACGGAACATCTATGCCGCCGACGGGCCCATGAATCTCGAGGCTTCCTTTGTAGTGGTTGTGCAACGCACATGCAATCATTCAATTACATTCATCATAATCTCCCGCGAAGACGCGATGAGCTTCGGCAAACTCGTAGTGACCGCGCGCCCTGGCATTAACTACCGTTATCCAACTTACTGATACGAACCGGTTCCTAGGGGCTCGATAGCAGACCTGAACAATACGTGTACTTGGGCCCATTACTTACAGTAATCATTA
+
6799:4&42I(8DI.'9I(2:;I(H'9I/'I(3F'8:6I(E&I(879:I)6I/'6@818:49H'2244:83<->:67778:5:9BI.&<I(=6;I):7I1'H'I'77;8585:47I):78.I(43D&=7H'6I)93I)G'4I(8I(7>9694&I(I(9<3:;52=I'8H'8;8I.&I0'32:G'4;<386G'7I'I(I1'56974I)F&7996I(8979978;6I(675I(4I)E&;76I(769:8;I(761I3(6<<H'495::+768058I(7I(9I1'6;54235858I(9:895I/'5H'6?I(I(:<3I):G'8:I'H'6I)7:8;>1286I)I'I(I(I':;I:+&54<;85846768I(53I(7I(76=663459I(I-&I-&7I(66I)69:7<I(836I,5
@simulated.57
TCCGACTCGTATGTCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCATGTAACACAGCCCACACGGTTATGGACGCTGAGCTAACATTAGACGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTAGAAGTATGCAGATAATTGGCCCGGTCGCGCCATAAGAAGCGGGACGCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCACCTATTGCTGAGGAGAGGTGCGTAACCGCAGTCTTCCAATATCCCGTGGTCAACTAGTATGCAGCTGTGGTACATTCTGGTGG
+
6I+:776865777656I(5787<75=8;1I:+&8765I(I1'I(45H'396I)7I(I+<878I)3:?;:I1(48:4I)I(58I'64:;6560B8I(8-I)32&613>I.&I(9>I'47:67I(;H'I(<4877<I(01767I'7*8I*72;5887:5;I'I)I(I.'I(;97:6H'::G'9I'44I/'645H'7I(;94>5577<97I(695I1(I(:968I'1:7I'F&:8I,<89H':8456:4H'=7;I(661>;8584@78693367<I(;6I(6:8I(856;8:465;I(9687I(I*75I(?35:3I(:8I(3:79;I(8;9I(66858H'G'589789I'G'I,746I.'67I'92H'*:824558876:::>I'07;8I)94I(:I(
@simulated.58
ACCCCACCGGGAAACGGGATGTGCCAAGGTAGATGTAGAATGTGTCAAAACTTGTGATAATCGGCGACGGGTGTTAACCTACTCCGCGATCACGGCCCCCGCACTATATCACGTCACTAAAGCGAACGCATTCTCGATGGCGTAATACGAGGCCACCTAACGTCCTTCAATGCGCACACATCCCGGTGCTGGACATTTAAAGGAGCGCTAGTCCCCGCGGGTAGCCAAGTTATGCTTGTAAACCACTCGACGACGAGTAGGTTGGCCCGTTTAACTCGACTCTCTCTGGTGGAGCCCGACCTCAGCTAACGAGCCTTAGGGATGTTCGCGCCAGTAACCCGCCAATTGGACCTGTCTGTTATTCACAGTCAAGTTGGGAATCCCTGTGGTACGCTGATA
+
6I<,'7H'I0'I6)8I.&648:6I(I(H'=:2>7=707I(<69619IF/(6F'7:;75I(9:I(6::=I/'91I(I(I(7896I'5=8<4775I(IH0)%97734628:887273<25I-&657I*4578I(553877I'95?I(55*8;I(G'5I(8I(:79I'I)2I(36=;623;588I1(I(5=76I)984I1(I-&I'8;:586698I;+&:5I1(B%;F&H'7I(7055I(8:I/'G'59<6?87772<<099H'I(I)I/'8I.&I)<93;::7;5:92<I(7I);8I0'77H'496:;8I(::;6I)H'&I/'4=9H'86:2I'687I)I-&3I'I(F'F&8I'6:>:67I(7H'5:;7:48I)4I'I1(I(9I/'<:4D&<46>:96976
@simulated.59
CCGCTATAAAACCAAGTTTAGCTGAATGACATGAAAGACCGGTATGTGAACAGTCTACCTTTCCCGACTAACATCGTGACTATGTGATAAGTATCAAAATCAACCCCCACCAGCATGTAATGGTAAATCTTTAAGAGACCAGACGGGCAAGCCTCTCAGTGCCTAAAGAAGTCGGTTGCCTGGGCCGTCACACCCCGACTTTAGGTTCATTGCTCGATTAATTGGTATTCGTTTGTGTATTCCGGCCTGAGATCGGGAGGATGGTGTTATTTGTCTACGGTCTACCACTTGATCTAGAAGCTCCGCCTTTTGCGGACCTCAGGTTTAAAGCTGCGGAAGCTAACGCTCGTAATCGGATGATTAACCACA
+
E&788;7I=,'I(I(6I1(36748F&8787849I3(34F'I):>:838I)<5:379;I(I1(I1'4/<;I(:786;;98476778987I(78775I:+&64I)II0)&8I,42:8845I(=I(:I3(=8I/'H'5465I)6;74I-&8H'4I(45729248I(8I.&0I(77;I(I(:H'8I2(I';559;=I;+&7<5I.',I'I(7:E&866956I(I)I(E&57I(59I-&956'8E&I(I(G'7565@84I/'AI(?8I(98I(5I5):9;<19F':<67I)<7I(45868;6I(437I(7I(I9*&99I';I'5::I(I3(I7*63936I'I(;::I(6295;3=I(36I'8587I(I(I(689
@simulated.60
TATCCTATCTTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTTCGCAAAATACCGTGTTCTAAGGCGTTAAAGCAAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTACCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTACCAGCATACCCCCCACGTAT
+
688I(7;:9I0'>75>I(87I(8>II1)&I1(I(7I)=:59I(6997I(677858:6IG0)%3576F'8737I'878I?-'8&H'<;6I(37I(G'8<I(I1(56I.&<73I2(I(7I(II3*&36465I(9I(I(37I(24I(77I'8;57:I0'77I'9728538698;I(6I.&78=I(4I:+&67798I(5<G'I)5;I)I'929927:H'6=:I'F&96:697661856I'7I(>;:6H'6:7H':I-&I(G'<93;I)=I(78:6@H'66=86I(8589I(89>6435I/'5I0'49=77?9I';47I(47I):6I-&5%II;/)&1I=,'I(;95>=467I)46;I-&55I(897H'3;934I';6I(8684I'85<9358@6I'427<2H'266I(49I(I*=I,=I':59813II9.)&6997:D
@simulated.61
CCAGGTACACCTGATCTTTCCCATTGTTGAGTGACAGGCACCCCTATACCAGAGTCGTAAGCGAATGCAAGTTCGGAGTGAGGTACTTGACAACCGTGGTCGATAAGTCAACGGGCCGAGCCTTGTATCATGATAGGAAGCTCGGTCATTCAATTCCACCTATCGCCCCAGACAAGGGCCCAGTTAGTCATTCTCGATCATACTGTGGCAAGGGACAGGTCTCGGGTGGAATACAACGCATAGCCGTCTCAAGGGAGTGAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCGATACTACCTTACAAGCCGGGCCAACGCACTATGGTCAGCTTATGTACCACCTCCGTTACACTTAGTGTTGTTTGCCCC
+
H'9I(7282I)75::9I.&I0'3I)3I(;80<<55BI*88I:+&6086G'2985<:77I(569I(:65I(6I'5F&39193I(789I(59:H'I(;2H'49697I(753I'8I/'I):;;I'I(?68667546;7E&G'56;9I(875I)3I(I(I(7I(979(6I:+&;8'5I)I0'I0':6I(6507:I(8;998:42633666I(8H'I/'75DI(7138I6*4I(I'38:G'68287:5G'79478E&I6*77B7:;I.&95I':7:>I(8?73>47773;5<3:H'::65774:I(I(3:I(8F'I2(I'I);62;7577G'11629E&99857I+<G'8I)8I'775:I(7898I*3I0'7I>,'
@simulated.62
CGTGATATAGTGCGGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAGTTTTTGACACATTCTACATCTACCTTGGCACATCCCGTTTCCCGGTGGGGTAGCTTCAATCGTCTGAGTGGGTAATGCCTTCGCACTGGTCAACTGTCGCGTTTGCCGCTAGTCGGTGATCACTTGGAGCCGCCCTACTCCTAGCGATCGTCAAGGGTACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCATCAAATAGTGTAACTTCACATGGTTCTCAACGCGATAAGCGCCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCTAACGCTAGAGACCC
+
87:86=2:66877II1)&I'6998:;76H'5<69I)I'G'56I/'4=96I(8:I(;4;<7I'6II4+'655:8;I(415:7;<>;F&I'I(45588I/'=I.&I0'I(9I9*&2<66I):I(9:29679:57I.'2I)53H'I(844849E&49G'669:8687I1(4I(757;788I(;960784H'I(4?H':I1(797;I(88:8=4<5985I(I.&8::I2(899H'I)2I)7<8H'67789988I);I0'8I':;68I)5:I'79368I-&498:87I(:I)83956I+I'=49G'69576:I,;86G'I'8:7::I(6959I1(7?29I'94G'18II3+'I4)H';I(397;I'5688I'+=3;5>C86I0'
@simulated.63
CTCTAAGGGTACGGTATGATCCAGTAGGTCCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGGTAGCCGGCACCGGCCCGGCTAACAGCGGGAGTCGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATAGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGACACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCC
+
84:4I(I0'7&7I(8661;;I'77=2I)6I(3;H'I(89G'G'8I(;;51:8778I'5H'5I'I)885I(E&7857>I(II8.(%795I(H'67I)I)I1(I(5:I(9861I.'78>%8I(588929I(93I(:I(4757I+9I(I(F'H'I<,'>34:G'A4I0'<999539I)8;2I(547589I;+&6>;76I(I3(7:7H'8I'6H'6I1(3787898:IH0)&7'I(I(6=95I/'I.'6976?77669I(I(I-&3719;;<;6I/'E&7:7I(4=H'57I1(I(6;;8955F'7;:I(9::8:8I(8758):8<:3F'78I)6I(G'F'4<I<+&:9325:3I(76I)I6):89I(4:I.'66?<I0';I)I'587I1'894246I(6557:H'8F'
@simulated.64
TGGGAAGACTCTGTTCTTCTGAAATTTATCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCTAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTCCGCGTGATTGTCCATGAAACACTCGGGCACCACATTGATCGACACTACCGGGTGGAGCCTCCCTTCGCGCGCACTGTTCCACCACTATTCGCTATCATTCGTACTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGCACTTCAGACCTTGACCTGCACACCTTGGTCCAGAAGGAAATGAAAGGTGCAGGGATATGCATCAATTAGCCTTAAATGATCCAGTACTGCCCGGGTGTATACCTTGTCCTTGCTGTCTGTGGGGCTT
+
5I/'H'6:17544I(3H'898I1(I-&:5I,53<G'4958>4997I'9;7:589I-&I)45II2*&9?2=I1'77I(;9;14G'348:I'I(I0'I(=I:+&794I.&;6I(H'D&77579&76H'188I(E&I(;7?<83I(4:9H'8;<95I(I(9:I'<2I(I(I(859<9:I'==H'669I1(969<5I/'99D&9=8H'7.6756:55;:I(I/':I'99E&6I3)I)55542749687I(I(6G'86:9I(:338<997H'574::7<87;I(:I'I(7I(:<H'575I'567I(I)6G'7I)36688I)9597I(I'18I(666;29I(I(I(&G'59I,I(I1(97I/'I)<783I0'5679:9669I(H'73I'I)I.&7A68I):::4446I.&I/':35<1<G'I(97I(I)89355675;I=,'6I(
@simulated.65
ATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCGACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATCGTCATTCAGCTAAACTTGGTTTTATAGCGGTTCTCCGAAAAGAGCAAACTATTCCGAGGCTGTACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCAGTTCTTTTTAATAGCGGGGTGCCAACCTTCCCT
+
9<9I(I)I,&876I8*&297068I(I0'7I'6I(I'74:I(9I,9I'28748549H':I):I.&6879G'947<I)I2(96I/'<I)7I(:6:9;98I1'9IF/)%I(2:I9*&5288:I);7926868<99&599974I(7323I2(I-&I(=86=649G'837599I'I(54I/'7:8'9465I(7641<I/'8I)I(I9*&8980;I(H':;G'7I>,'8449I0'436I'I'96G'5:3&6I(I(7I=,'8F'I)7I)88856669:82I(97I0'55I'9I';G'F'33:3=F&456I<,&F':I'685H'I9+&:46I/'97I)7II1*&I';857I8*&67I'I)I'I(I-&7
@simulated.66
AGGGCCAGGCGGACACCTGCCTTGAAGTGACGACATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGGATAGCCTTTAAATAACCATGCACCGTAGATTATCCTACGCCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTACGGGACGCCGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATAGTATAGGTGGGAGAAAGACACGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATAGATGCAAACGC
+
9I2(I(<I(6I)1>6I(59I(F'7I(7:3467::67E&?0:7=8867674347I(9?::2;6234<I5):407;657<:8744759I8*&?:64587I/'88:=I)I/'I.&9I'F'5;49CI(86949H'9<I(39<<I(7;6;8:5867:I(87H'6I2(93I'95;I*667I(7;974:896I(::567::9<55I(7778799647I/'5I(I(:8:5'I0'675I'II5,'424I'266I)8:I(<5I(:3341::8I)766&4693;I)9I.'87I.&9988&627I(65836:7I.'27758I-&64:3;8:6I)I(2H'634=6I(8&;3734I.'967
@simulated.67
TGGTCTGTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACTAGACAAAACAACGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGTCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTCTGCTCGTCGTACCAAATCGTGCCCGCGTTTTTCCTTATGGAAGATAGTCGCCCACGATGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGTCCGTGTCCGGCCATAAACAGCCGGGGCAAACAACACTAAGTGTAACG
+
:I(595:I+5:I)I)=I?-'I(4I'44697<I(69D&8;4H'@77I*<:;9D&I.'7F&7I/'I2(9I0'>I(=I':58I(I>,'73=;897:94I(8I(H'45I(I/'66797?=I1'38I'6;I(5I0'6I(86I)I(::928<795<987I(36:54%5476I>,'8I(&<I(30I(:I2(779948I(6I'38824:I(0664I+I(8I.'<'I)I(I3(4:786H':81961I4)295-96I(I(8G'I'6976;;398895;:68H'I.'46877I.&545II3+&I(I(97I(I(>67658&6I1(80&65=6675I'5998<4=78I/'I*646;>:;92I'518;4;<4<8I/'<779889I+6I'36:;I'I(I(87I7*7::I'I<,'2I0'6I(578;I(620;I):<
@simulated.68
GCCACGGCCCAGCGCTAATGTTAGGCTCAGCGTCCATAACCGTGTGGGCTGTGTTACATGGGAATCCTAGCCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGACACGGAACATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCTAACAATACTATGAGCCCGTTGCTAGTTCCGTGTGGAAACGGATCGCTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTCTGAAATTTATCCGCGCCATACTGAGATTCG
+
:I'78I(I.&481;@5I)9:I+8I'287;9;75I(99I'I(699:I/'45=88H'3889I.&E&<I(594I(85F'I/'F'8:87I?-':9669;:4;59I'8<528>67<7<;7I(27:5I)I)78I(698H'G'H'564754I)I(659875876<I(768773I;+&8:4I*8I);7F&I.&I(:86I(5;I.&137956:9:I3(I'6&I'4I'77?9=;=79I1(7H'8=675I'I)'485I(I.&:I+88556789I.'3I(773I'6I'4H'76896H';746:<7:78186I'=:I)08:995639E&273I'53I)6I(8I(82I0'884;8983I(H'896G'9I<,':358<@<5:I)I(:I-&G'4>95:46I(6D688I/'I-&:7I,35;E&474187999I(45
@simulated.69
CCCTTGTCGACTACGGAGCGCTCAAGACCAAACCTGGGTCGTCCATGCGCACCTTGGTGTTGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGACTCGGGTGTATAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTACGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCATAGGGGGGCTTTCTTTTCACTCAGAAA
+
I.&I)<:8<:87::I'2359;;5I(88I*I/'I(8I/'3:%7I)666:53<I)I'I(86H'I@-'73@3I(;<I(I-&I)I(97<;54I2(656<I):;54;<8I(528:9879797398A4H'9A9255I0'H'7I;+&=4G':I0'57;(86I0'4:3A74I/'84;8558I)968I-&569<;9:47A858.I(685;5<I.&9H'<:I(:>:I(895I)96958:6947:6;36646:I/'676I-&5:H'5:39I*:768<9:I1(I9*&5I(&;686:;682:64I(I/'756D&48<I<,'5II4+'4957I(469G'5I(5758826I)8I2(:54;96I+7:92939;6586747I.&889I(83G'I+98578;428876II8-(%6I/'7I<,&6897684I0'
@simulated.70
ATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAATAGTGGTAGGAACAGTGCGCGCGAAGGGAGGCTCCACCCGGTAGTGTCGATCAATGTGGTGCCCGAGTGTTTCATGGACAACTCACGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGCAACCCAACCTAGTGGATCGATTACGGATAGCCCCCTCGCCTTTAGCTGCGATCTCAGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCCCTAAGACAAG
+
:9I0'98:4I)I.&61I1(E&I0'9;I)I(I(I*;8:56:H'97I(G'533;I);36:8H'3I(;I(I(748I)974I':8I'8F&H'<I':8;<7:6886I);8952796G'668=I)2&G'I(8=8:38786:7I(I/'7I'92I(:I.&I(978796956<<I'5:6I(46I/'6:863I-&:37I':4I(&;8586<I'I)H'68I'91I'E&:5:78I'C76I(689984E&I)I(:54G':<66778I)I(I(43I/'763I9+&4I'I0'I(I(>77=I'3875;I)88I,5964II2*&8(5I(I0'6929797D9>57>;?5:I(486I0'47I1(I3(:96I(;I(8<9755;I)I0'6G'I(89<78894<I=,'<I(777I(4
@simulated.71
TGTGGCGGGGTTTACTGTCAGGCAGGACCTCTGTCTAAGTCATTACTTACCCGCGCGACGCAGTCAATTACTCTATGCATTTGGATAAAGCAATATAGGCATGAAAGTCTCGCATACATTACCGGCACGATCATTTTTTCTCGTGACCATCAGCGTGATTGAAGTTCTCGCACACTCCGAATTTCCATGTTGTCACCGGGAGAGACGTACGATCTAGCACTGGCGCAACCATAAACTCGTTCAATCTAGCTGGAGTTTCAATTTAGAAATACATCTGCGGGTAGGCAACCCAAAGGTGTTTGTGGTTAATCATCCGATTACGAGCGTTAGCTTCCGCAGCTTTTAAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCT
+
268I(9I=,'I.&4065659I'6:I*8I(8?A6777I)=::;I(7>I(9I0'653::68826585I(I(6:66%876?6I-&I)5:I/'56I(53>3I':53;I.'798:84765599I(:I(H'88688625II:.)&8975599G'<D7;::&977E&7I'7I*85;4884<86I(7I(I/'H'679I*;73=G'I5)8=76;8;:577=:1=574:>9H'687I(I(87I/';871G'9I'83<96<<I*85I/':I(I.'45I1(9984468;7I1(9>I'4I(I/'I/'H'87I1(94G'F'I(71:7I'36H'7848871I'757I(H'55716I=,'I.'I*454H'6I(66I;+&I)5I'65;G'69;;:;=I(54I)947;I(37699;I@-'5G';5I'42H'7I1(59677
@simulated.72
AAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTCGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCACAGGGTGCGATATCGATGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATACCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACAC
+
I-&6979867:888=87;I*798527I/':G'574;776I)2I)658I'8518IF/)4I7*:76I(:95I/'I(8123;3;9>766I'=I=,'I/'8<76447I(56:5I)68I,<=:I/'<;7%4:48:4<49567<499I)864H';;9I(15I(=I2(13<8:9I'96<:08/499:457*I0';48I(9764857I/'579877I/'6:77BI-&=G'65I:+&7I)I/'9:3957F'87474:.96755:94;I*;667439I(C598I0'7967=8I(I(I/'I(47I';;?3IC.(I'68I(I(I(96<=;33I(58;I0';I(I/'I':7H'A458158I';99.659A9I(I6)I(551=I/';=5
@simulated.73
TCCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGTAGCCGGCACCGGCCCGGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATACGGAGGATTCGGGTGTGTCGCAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACT
+
:H'5:I(H'76I(I(9I)5<7755325I'7I(7I'I(749I)I)87856I(II7-(6?=I(F'<8I(I(I.'I(46I(8968I/'6749G'?54638I*38I'9I(3645I'8I)I(I'I(I9*&9846I'43I.&=2>>:46G'785I(:4<795I<+&:4<83H'I/':69*I)9I)7I(7I.&695=:476IF/);I'H'8:86I5)I1'4<5<99066=F'I'I-&<95990348I3(G'6:7I(55I'85I/'I*706;97<I(4:3I(894:48I(=89738567I(24I)6I*I(I(77I=,'69777=4I'7:I(I:+&<=:H':5I,&;454I.&7I(F&82;I/';;5>66I(5;356I)9H'I(:6568768I.'9259>I.&8396;4;I'89:?
@simulated.74
TCGACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCACTTCGAAATGTTCCCGAGGGTGATCCATATGCTCCCTTAAAATCGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCGGATTTCTGAGTGAAAAGAAAGCCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATGTACATCGCCGATAATC
+
96(8I'5895F&4;7::6;6@89I(898:;1I(98I(I(447I(85:;:?53;5<9:I(68I(:I'1=I((7I-&9:I'I/':6I/'8916I)9389369I0'I(I9*&44I,957I@-'8I(I(I(H'711:76837I(5:76H'5I)9I(5H'3I1(96I(F'7=4597H'6:9;4864I.&5CI)6I/'5759368I=,'=I.':II:.)&<53778<;9968I(I)<8H'9;:I.&<8<829887=57443I*;3386<I/'2I(87699:9F':I*:69I):8:7II5,'5I:+&97<I(;17I0'I'756:>5657<55F'3I;+&I0'52;7758I)3787I'=7I.&2:4I/'5:69663:45;8499=8;8F&957I)95
@simulated.75
CAGGTACACCTGATCTTTCCATTAGTTGAGTGACAGGCACCCTATACCAGAGTCGTAAGCGAATGCAAGTTCGGAGTGAGGTACTTGACAACCGTGGTCGATAAGTCAACGGGCCGAGCCTTGTATCATGATAGGAAGCTCGGTCATTCAATTCCACCTATGCCCCAGCAAGGGCCCAGTTAGTCATTCTCGATCATACTGTGGCAAGGGACAAGGTCTCGGGTGGAATACAACGCTATAGCCGTCTCAAGGGAGTGAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCGATACGTACCTTACAAGCCGGACCAACGCACTATGGTCAGCTTATGTACCACCTCCGTTACACTTAGTGTTG
+
27I(6466I'5;963I/'I+2H''=I(623775;;E&53I5)7:7>E&;7:87<89H'8:0I'86:I(5I(8I(>6774H'768I(886I(I'38I(55584G'486I'9I.&I(458I(I*95:784;7499I*I*6:97I'57;I)4I(I(I)8I(6647I:+&636I(I0'I1(<0H':4875I'894:8559387677I':I(I-&:3F'I(496:I5)1I'I*999I'969&;:56I'5;7:=I)I5)36=796I/'49I(:5=8I(986938738762893I(559946)65I(I)89I*4I'I,&I'H'9599951:I'=<578I'5;=85H'6H':I(<G'?874I(9:64I(9
@simulated.76
CGTGTCCGGCCATAAAACAGCCGGGGACAAACAACACTAAGTGTAACGGAGGTGGTACATAAGCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGCTCACTCCCCTTGAGACGGCTATGCGTTGTATTCCACCCCGAGACCTTGTCCCTTGCCACAGTATGATCGAGAATGACTAACTGGGCCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTAGCCTGTCACTCAACAATGGGAAAGATCAGGTGTACCTGGAG
+
D57;:I*I(I';8I9*&7;8I'I;+&&:I.&6I(73:9I'96<5H'6F&7I(7I'98>=8I(86767G'77;66886I)I'I1'F'4I(33I)I(86586939I(;8;475:86669749I(5188I'48I+896794I;+&I(7;76;H'529:668I(937H'I'<I<,'871;I(H':8I4)G'7I(9=9936;6;55965I(89456I(64I0'I.&F&666I9*&7768I)7I(I)I(6I(48:I(387;I)I(7:9:58575>7I)G'656I(I.':I(:77I(:9398I'84I(G'>76I)=47I(74:<9I):I(5H'<9:I)8?7I(49355625H';7<6I=,'8(8I(677<9787I(1I(6I-&I0'68:37I)519;I(;H'99
@simulated.77
GCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCACCTATTGCTGAGGAGAGGTGCGTAACCGCAGTCTTCCAAATATCCCGTGGTCAATAGTATGCAGCTGTGGTACATTCTGGTGGCTGGATTTGTACTTGAAGACTACGAAGGATCATCCGGCCCCCGCTCAAAATACCATCAGGGCTTTCGGTCCGCTCTTAGGCAGAAGTTCGTAAAACCCTAAGTGCGTTTTGCGTACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGCTGCTACTGCC
+
2825I3(I)6885I(647I(I(5;I/'555I(667834?I(518I(44558:5::2:4:776:85F'=8I(C20G'75<433<87;I);759I'I(58I(7587:I);5I(05835I(695I(79;98I(I'585;73H'I(I4)758I.'7:I+:9I(<;64866;8>85=8I)7868I'96H'7I(75E&4I/'6651I(0F&8:>7754H'I(7@:4<I(I(II1)&3995IB.(4>I(7659I1(7I1'4I(2I(5<7;H'4H'978I(;I(256I>-'I-&+G'99656I;+&8;8%:638I1(75958:5<<8526I)6I)86;H'8H'387I1(:I'7I);3I':99I)H'I'8:4I=,'G':9I0'I(I.&F'8I(I0'I.'E&I0'745:5:;98F'
@simulated.78
GGAGCCCGACCTCAGCTAACGAGCCTTGGGATGTTCGCGCCAGTAACCCGCCAATTGGACCTGTCTGTTATTCACAGTCAAGTTGGGAATCCCTGTGGTACGCTGATAAAGAAGTGACTTACGTCCAATTCCGATCCCGTATCCAAAGAGTCTCACCGGAACTTGGGCAGCTGTTTTAAAGTCCGAGCTGTGTGGCGGGGTTTACTGTCAGGCAGGACCTCTGTCGTAAGTCATTACTTACCCGCGCGACGCAGTCAATTACTCATGCATTTGGATAAAGCAATATAGGCATGAAAGTCTCGCATACATTACCGGCACGATCATTTTTTCTACGTGACCATTCAGCTGATTGAAGTTCTCGCACACTCCGAATTTCCATGTTGTCACCGGGAGAGACGTACGATCTAGCAC
+
G'68I0'97I(4;6499I):;3=I(I)I0'7<2I'369:I':7;I(I1'7I)I'I)I'7G'=94496I(4F&27>2869G'6I'I/'I(6I0':87I'8::95<697I5)8H'71888I(7886I'I'H'I(967I.&687AI)I/'4:84;598I'I(I(<I)I0'96:5:9I:+&I/'67E&76686765=F':I<,'I0'39:98:5I(57I)7I(415576-=I(=676I(:;G'6I2(;6;574488>995G'E&=596275:5I0'G'62I.'73I(;947H'5729I1(8788467638<7H'8I(I)489:8;98II;/)&78+9/64;I(2I(2799738I(:I(1I)8946965859I(8I(I0'I(785E&5:64I*I2(4<548676694696377=64
@simulated.79
AGTGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGTACAAACGCTATCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAAC
+
1%58;8456939G'I(37I(:9;I.&2;2486>88;8569;G'7565=0I/'=I'84:;8;2I(6G'>49F'8669II1)&4I8*&<77G'9:9I/'I(5:6788<950;8I(6I;+&I.&63641;9I'6676G'67I/'774I1'815;85:87773665=;96I(/77I(899I(:4I(7I/'76:5:5H'8492;5489<7634I0'889G':733676I3(=9:516I2(8968:I2(:I'8;I;+&;I'I1(5<555;I'82968:87;862;99:I(;4:77:<I(87*9@I/'466577I(I(I.'G'71I(7765II4+'H'67I(G'I(7:@:84;I(6:<I2(6I(I-&I(63G'6387>67H'897487:84I)I.'I'265;I/'7
@simulated.80
TCTGATGTACCAATACTCTCGCATATCCGCCGGACACTAAGATCTGGCACCCCTAAGCTGGGCTTTTTCTGAATTCATCAGGCCGTGAGGCTGGTATGGGGTGCAACTTCGCTTCCAAGGAGTCCGGCTTTTCCTCCGCGCGGTCGCTACCATATAGGAGAGCACATACACCGGTGGGTAATACGCGTTACACCGTGGGCGTCTTAACCCTACCGGCAAGCCTACCATCAAGTAATGGAATGAGTATCCTGCGGGCCCTTCTTTAGTTTCTCGCTAATACGATATTATCCCATTCAGTATGTATTCAATCTAGGTTAGCAGATGCCTAGCAGGGTCTTGACG
+
877954886I)I)::5985837479:I)8I)I)989@7F':3746G'85I;+&:I+759I0';II5,':87I(I(4;244I(I(:3<=I)<8I(7;8I:+&294I(:I(682I'I(H'I(959I(H'1I:+&I(9I)6:97I(694=93I(<392;I)8:;68:9<59<5I(I(8I/'7I)639=88I(=;4I(85I0'4836H'E&I0'86I(I)6G'5I*59I(86:I'87I'9I*I(7=;'8;9E&;=3I2(I-&G':I.&4:I-&:49677I(8.26864I(:<I0'7I(05?497744H'7I(9735I'I):97>5;47I)67889I1(;8I(9>56
@simulated.81
TCACAGGTGCGAACTCAGTAATCCACACGCTCTGGATCCTATCGGATGGGACCTTTAGAATGTTCCGTTTCCCGTCAACTTGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAATGAATGGAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCATACCAGATGAACGCTGTCAAAATATCCGCCTATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCAC
+
487<5I(954;H':78;(5H'8G'85>973769H':8I(795;I(18I/'6I'I.&86G'89I)H';I/'I/';85H'7I(89;4I)74I(<896877789I)I0'9I0'5:72I(I)<;9::;67;;96766821989I(=I'688I.&8;68I)35;H'757I)9I(I(=8:I);958858:6797I7*:7I)8I(58838685I(I)55I'68I9*&I+89:48I(:F'59I/'95;G'289I'I.&9;I/'69:F'2=2:I(6987I(:47:9:63I)75=868499I,9<486I(5:7=;64I8*&;64H'7I('979I/'9:5598I'I(7/78:469989:581:I0'96
@simulated.82
AGCTGACTATAGTCGTCGGTCGTCTCGCATATCTAGACACCTACCTGAAGGGCTATCCGGGGTGCATCATGCGTAAGTTTTATGAACAGAGAAGGTCTGAGAAGGGCCAGCGGACACCTGCCTTGAAGTGACGACATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGGATAGCCTTTAAATAACCATGCAACCGTAGATTATACCTACGCCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGA
+
:38::<5:76D;65585I(=:5%6946:5;6;=4/2<9;I(96I,7:I(I-&1995I(I<,'7980459:9994I)5I9+&47:E&=:66:I'I(7337:7H'I2(F'6D9G'537I(67I(I'9I)5;486956:7I(77996;76;194725I)75>72:86339I.&66;5;6>6<88976956I;+&8:8:599I,&;6:6I(I1'I-&5I(I(694;I'I(=5535I(;8'I(45<3H':858584688:I(58I(3I1'95I(<=7I(:97I)626647847I(88:35658387I)579554493;I0'5I'I(3:59I3(968I(II9.(%:79I(716I(<8H'67I)567::867I(557>7678I(=I0'4
@simulated.83
GCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGAGTCTAGAGGAACAGCTTCCGTAATACAATCTGTATAATGTAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTCATTGTATTCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGGCTCATCGAATGCACTCACGAAATGCTGTAACAGCTCGCGCTGCTCAAAGATTGTTCCCGCAACTGGCAACAGCCCCTTTCAGTTGTCAAATCAACATCCGCGTCGAGGCTAGGTACGGTCGCGGCATTCACCCGTCGGAACTAACGCAGAGTCTAGAGCAGCCACATAAAAATA
+
;97:6I0'9I(:36<I(I(I)8:3H'5I(I-&4I'I):7;I(<I1(I(6I(::':5<7<6H'I)==89H'H'35I(67:I(8=8:<97I(:25I+825I/'44795I(3I'7=<8I'I'5525;;4=7I)366I'988I(47889I'8I1(49593I(8I)68I'G'::I(;79481788I/'6579565I)969:4:3:67I.'678<7:I)76077<73:=9:5:1I.'77I'5I(I.'53I(46I(BI'57;I9+&I/'53;I(598I/';<H'>96I'>4<=6;7I'690I(675I(965:I)6=I(94I1(9>3I(E&7:I,76D496574:1:5;4:;I)6:<9II2*&95
@simulated.84
CTAGCCTCGACGCGGATGTTGATTTGACAACTGAAAGGGGCTGTTGGCCAGTTGCGGGAACAATCTTTGAGCAGCGCGAGCTGTTACAGCATTTCGTGAGTGCATTCGATGAGCCCTGCATGTACGGTAGGTTCTGGTAACTCATCCCGTTACGTGAATACAATGAGGTCGACGATCAATTCTCTGGCGGTACGTGGGCAGTTTACATTATACAGATTGTATTACGGAAGCTGTTCCTCTAGATCTTATTAAATAATAGCCAACAAACCGTTGTCGGTTCCGCGCTTGAAATGCGCGCGCCTGCGTACGAGTCATGTGCATGCCCGAATAGCCGACCCGGTTCATCGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGAGGAACATCTATGCC
+
9:99F'47>:693I(3;;I(99I/'78;F'8::I.&I:+&832I'I*I(63H'37I3(H'5I'75I/'396;138=684699>I(5368<2I/';>6;8554:8I'4956576I0'7:58<88:8G'4:I(I(49I*1I(89874I1'7I(558:8I(945H';:6I(9;7749<68I(I(3567I)9I'4;495I/':>:I-&29;I(5783<6<I'5<:I'45G'I(59?6I*H'357;=13:I(9I(I/'8H'::9I+I(6I/'I'2I+;36I'G'I'7653I*<I.&8:;7993;I(7836;6677'697:476<996I.&5H'94:I)75I0'I(I)5:>+6338737I)8479H'57I(99I(;I'79H'I(8I'8H'7:98;5I'I':8:856:8I*
@simulated.85
TGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTAAGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAATAGTGGTGGAACAGTGCGCGCGAAGGGAGGCTCCACCCGGTAGTGTACGATCAATGTGGTGCCCGAGTGTTTCATGGACAATCACGCGGAACCTAGAATGCCTTCACTCAAGCACGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGCAACCCAACCTAGTGGAT
+
8479:?796;67998I/'3I(7:9I(9I8*&6;696:647I(F'67I(I(62<777I3(I0'656677;G'54I(8I,I(I(77I(I)893956486I/';366I(I3(68I/'I)I2(70I'I(I(I(77<979I(64H'I(;7;5I(87974I(2I)9I'H'::2I(998I(:<I(9I(H'1I*89;?36;287I(7759:959G'<585I(<I)I)8744<8;:4;8I)I0';F'69I(.I0'I'798294+6>373H'888I);5I.&7:;7;I2(=56I'9;I(96486:I(I)I)%4>G'1=I'I):96::I(44;'C48:57:I(I'I(8=2I(<C:57;2I'H'I)58I0'774I?-'5G'I0'I(I):35<I(47
@simulated.86
ATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACGTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGACATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCGTTCCGTAATACAATCTGTATAATGTAAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTACATTGTATTCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGCTCATCGAATGCACTCACGAAATGCTGTAACAGCTCGCGCTGCTCAAAGATTGTTCCCGCAACTGGCCAACAGCCCCTTTCAGTTGTCAAATCAACATCCGCGTCGAGGCTAGGTAC
+
977H'I'44;68<I':G'1I)I(85I(5I(>;I(79I(6'69<I)4646;834;7I(I)I/'65I(>69I(9I1('7668226:74:964:7663;I(7934596:I.'9H'<8=6I'I)H'658I'5I(I-&8I(F&36=I(5I.&I'7I(:83<8457I)I(=;88(I(I(85I';67I)6535;46H'783I1'8:8I/'@6974H'7F&5885H'I(6988<7856I);*::G'28;I(57684I(<I0';:656H'6I(87I(I(66H'368;9:9<3I+<7;=466F'38;66:4755I0'9776:7H'887?659777:657?I0'<7I(2I(I0'98I(97I(I'I(8@8I:+&I.&:9<I'486I2(59I(475I(959788:G'477I+529
@simulated.87
CACCAGAGAGAGTCGAGTTAAACGGGCCAACCTACTCGTCGTCGAGTGGTTTACAAGCATAACTTGGCACCCGCGGGGACTAGCGCTCCTTTAAATGTCCAGCACCGGGATGTGTGCGTCATTGAAGGACGTTAGGTGGCCTCTATTACGCCATCGAGAATGCGTTCGCTTTAGTGACGTGATATAGTGCGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAGTTTTTGACACATTCTACATCTACCTTGGCACATCCCGTTTCCCGGTGGGGTAGCTTCAATCGTCTGAGTGGGTAATGCCTTCGCACTGGTCAACTGTCGCGTTTGCCGCTAGTCGGTGAGTCACTTGGAGCCGCCCTACTCCTAGCGATCGTCAAGGGTA
+
;8I'85686>70;397;I)I/'3I1(H'I(G'53:3783:67=::76I(I-&77I(6:6:I(9G'I*78I-&:4I;+&:75887557I)I.'I1(6;AI'85<2I*I/'388873347-86I)7I*I)478F&8H'9H'G'=85:I'758I(368<<2I(<4;3I(548I0'7<69599<:97;2:6:78IE/(I(;77?6<:7I(:535I(I'I'76I-&5779I'5<I(6:5;4E&5II2*&688835E&568683:28I)I(E&774A9I/'<I.&I0'I(9I?-'8617I(8I'8=6893;880I1(;I)7=I'I*65349<D&98I'75855475I.'3I(5<9:783I*:<7%67;8H'H'6>I(6I2(?947I):6;85238678I(I.&@A
@simulated.88
CAGCAGAAACATGCATCGGCAAGCCTTGGGCGGGCGCCCGAGTAGCTTAATGTACCAAGGCTGTCCGTCTGCAACCTAGTTCCGAGCAGGACTCAGCGCTGAATAACTACAACTTGGTAAGATGGGATGTCGAGACTGACCAACCCATCAAACCTTGCAATTAGCGGTGATTTCCTGGGGAGTGAAGCGACCGAAGTCGGGTGCATTAGTCATACGTGGGGGTATGCTGGTAAACTTGGACAACATGGAGACAGGCACTGACGAGCCGCACTTCGCCTCACGAACAGAACGCCCGTCTCATGATGTGGAAAATGGGGGGACCCTCAACATTACTCCATGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGGCAAC
+
978658I-&477;;679F'7I'7I(I)I.':I-&:<I/':75:8?;I)I(8788I'I(H'798;G'4:.766I+I,992G'I'726?7I)930;:56:74?H'7I(8;35I'9H'I(7F'>6;I/'<:64;17;=&756I(H'I0'66>I/'I)I(65F'H'899I):9:I/'I'5I=,'4:66H'9668I(4I(<4;I2(5944I)75:464;996II6,'163:49H'8I/'<I)I*;2I'565E&:87B8I'53194';8:8G'86;9I(<1I'44;=8I(6<7I'9;I0'629C6989;745I(I9*&5II:.)&;I.'46I(46I(67:I'689627;I-&;I/';:38674H'96<3I(8459;I(36548H':I(6
@simulated.89
TGTCGAATCTCAGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCCCTAAGACAAGGCATACGCTGGGTCAATGGATTCGAATGCAATGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATAGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTGTTGAATTTCACGATCGCGGTCTTACTCCGGGCCTCAATAAGCGAAAAGACGTACCTAGAGTCACTAACCGTGCTCGGAATTCTGAATGTTCCGTGTCCGACTCGTATGTCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAACACAGCCCACACGGTTATGGACGCTGAGCCTAACATTAGCGCTGGCCGTG
+
99&9;I(896<93995H'698I1(26I4)I.&45<D&2I'98=;5<9H'I.'<I(I*;:4783944I:+&4I(4;9I(I(52959996I,&:3I(3I(<I(43I'686H':85393>34I(76I';679544397877I(66966I(4I*9I(:15H'>I.'58799836I/'5I-&H'3;<I'I'=@946I(5I1(::76<847;E&8H'8I)I1'8<7987938I,77I(454I)I2(I(63I(7I(:63I<,&875<65H'<;88;97866I)F'648687I(I(H'>16I(84I(I(73;:H'5226;6997755:I(7949562556<I9+&9666G'I/'I(57I(;64I'9I(I.&81;3E&581>7I0'7929I)I(>4I'539;759<I(=I(96G'5=8695I,I)77<
@simulated.90
TGGCCATCCTATTTTAACATAGTTATTAGACCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCATACCCAGATGAACGCTAGTCAAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTTAAGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCTAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAA
+
3I)I(88I'83I;+&I(77779I(7F&;8&I0'=77I(758I(I0'89I/'458I(74=8I)37<;I)795765:5H'735467?>5I0'68<68H':585%778I<+&954I'8I(668I1'6::5>4I'I(476:;86948::5;87I1';H';:5I(8I;+&<87729776H'I'79I)I(776738I/'I/';96975:I):;I(7I/'F&H'6:H'H'865765<67I3(67=6I*I.&29I1(I'I0'75I(I((G'I(87:7=8I(23I*I';=45I)586;<H'5H'8H'I(864H'66<I)95I(<I(I(6I(645887=;::I(61<734=3I(
@simulated.91
GTTCTCCGAAAAGAGCAAACTATTCCGAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCAGTTCTTTTTAATAGCGGGGTGCCAACCTTCCCTGAAACGTGGATTAATCGGGCCTCTGGTACCGTCAGTTCTCAATAGCGACAGAACACTGATCTGGGGGCCCAGCGAGTGTGGGCGCTTGCGCTATACGACTAATTGGAAGACATACGTCAAGGGGTTGTCCCGTGGAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTT
+
4H'<<I(8I<,'4<59I1(587I(I)55I(8527I*H':I=,'9I'G'8I(62<885;5<66I);9I-&8<I(7I):H'I'<::6:I(883I=,'E&3G'69;I)I>,'4<6I0'59I)8II2*&I(<996I@-':<I'I(I(I'I/'6:I.'6<<I'7I*H'<7I/'I)<73I(<8I(06578H'676I(98:447=:5I(45249<;47IH0)&I1'96796%6?5I.';=9I):33;9978668%5I)I(H'H'9;:5387345I)I8*&I)95I/'93I'I,7997635<6I1'I(6F'78585I(=57I/'6I)I(I(A6<88H'=8A655:5535;8I(:H'534I)H'I(5I)6I(
@simulated.92
GCAGGATACCTGGTACTGGTGGGTTAACTGGGCATGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCATGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATGAACGCGAGCTCCACGTGTTTTTCACCACCCACCTGGCATCACCCGTCTTATCTGAGTTCAGGACAGTGTCACTTTATAGGTCGGACCCCTCAGCAGAAACATGCATCGGCAAGCCTTGGGCGGGCGCCCGAGTACGCTTAATGTACCAAGGCTGTCCGTCTGCAAACCCTAGTTCCGAGCAGGACTCAGCGCTGAATAACTACAACTTGGTAAGATGGGATGTCGAGATGACCAACCCATCAAACCTTGCAAGT
+
:7:H'8;5I'=I(9487I':I/'I)H'24I-&;66I)68885I0'I/'1;I'3>I0'1I(5:623439I(867;8I(1I(I(8;78;:I)6I(656I(H'79=676986I)7658A;F'83I(48/<8;69I(4:;77II2*&77H'6I1(8H'9I(;7>98I2(78<H'85:4:98I':8F'79::292668I/'6:9H'&8I(<I9+&286:789I.'9<598739I)7G'9I(I(I/'5I.'<;I/'27448&58I'I(8857I(I(I(7484I'316;48I.&I3(713E&I'=5689I(84784<<@22:F'4I)8847I(?I(I(6H'?:<I.'63<564:3675;H'H'I0'9:9I1(I)I(;6I'(7
@simulated.93
ACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCAGGAAATCACCGCTAATTGCAAGTTTGATGGGTTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTGGTGAAAAACACGTGGAGCTCGCGTTCATTACGCTGAACAGTAGTCATTCCACTAACGGTATCATGGAATAATACTATTGCGAGCTCTTGAAACATTACAAAGGGCATGTCCATGCCCAGTTAACCCACCAGTACCAGGTATCCTGCTGCGAA
+
7379947678I(8099I-&49<I'5I'9769I(6375I6)5I(I0'::8G'7:5I'I);9I'DI1(:98I/'F'I(26794666;483I-&579H'7I(I*6I(677;I(:I)25745;6398;I'56:56G'I(85<I0'I-&94<297I(7:8;I(I(I(50::I(G'8573397I-&87I/'=I1(H'H'9I(;I)85449<:6I/'89977;5I7*&;I(;I)578I.'56645;8:5:I(45G':878:;;H'<4<I/'86387G';G'7I-&7I):9II4+'8>833I)8<967;53G'66I)957779G'578::7781I(H'834I(=G'794889I(G'8I(99552I(7;869749I(9I1(64I(>3I3(I/'378:9I(595I0'57I(I)I0'8H'260;I)6I(394I(:4555=8I(
@simulated.94
ATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCAGTTACGTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGCTCGCAGTCGCCTGTCTCCATGTTCGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAATCACCGCTAATTGCAAGGTTTGATGGGTTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTC
+
5=87:567I(965I(I(8688:<543<73I(9I(9898I(758I*<I/'I'I)<56=I(8I*43689'I(73%9:8I(9955I':;66461I/':I0'8<286:9I':89I(8:I(3;I0'4II7-(%8I<,'I(62877;53I'<-2I1'6<I(=:8H'56486I'5=H'9:73D2;486579&9G'87:9:I(72=I((79H'I(<I-&5F&<9:776II7-(%;55:9<77<:G'9368I5):@5I'4H'9574I(;5<5IA-'4H'I,776I(=7;I(F'82I(G'I2(0:7I2(G'I';8369=7:15<?I.&=83G':H'I(4I'9459H':I(87;68782626I(9976<I(I':8:I-&I.';45464I(9<38I(I)I(88;6I'I(9/58597I0':9I1(;I/'I(I(=G';I(758:C4;6I.'8
@simulated.95
GACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGTCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGCCGCTGAAACACGGAGCCATGAAAACGTTCGAATTAACAGCCGACCGTGTTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTGCGTTCACACTGAAATCGATCTAACTGATAGTATGAACGCGTAGTTGCCGTGCGCAAAGCAACCGCCTGGTGATCCTAGCTTTTTCCCATTCAGACGAGGTTGGCAAGTTACTGCGTATTGCATGAGCCAGATAACCCATTGACTTGGACCAGTCCTTTGCAGT
+
96I)5?;7;74I'3845I0'8290;6H'E&I0'I(55I(489:II1)&I(67I)G'H'::&9638>I)58:I-&4I)I2(H'79I)7<388<:G':253>6858G'I,I*6758I,&97:I(48I(75:I9*&9@F'66I(I(I(478I)4;I(=79I(89898::7I(;5>8I';<I(F&688<7237:7746I(885I(6687153I.&68>;8;:I(786;4509466I(77:9795I(9I(:3<736I/'87I(I':I'8F'3995H';796II4+'I1(6I(;:9;365I(I(I(;F&<I(78==8676I(6787=57E&4958E&I3(6I(:94I'I'0I(=88I(I.'4:246
@simulated.96
TAGGTGGCCTCTATTACGCCATCGAGAATGCGTTCGCTTTAGTGACGTGATATAGTGCGGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAGTTTTGACACATTCTACATCGTACCTTGGCACATACCCGTTTCCCGGTGGGTAGCTTCAATCGTCTGAGTCGGGTAATGCTTCGCACTGGTCGAACTGTCGCGTTTGCCGCTAGTCGGTGATCACTTGGAGCCGCCCTACTCCTAGCGATCGTCAAGGGTACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCACTCAAATAGTGTAACTTCACATGGTTCTCAACGCGATAAGCGCCTTCGTATCTATCTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCT
+
94I*7I(I(;548H'959I)585727I(727<I'455I3(576;8:850361382479II1*&I)6<:39:97I)8375G'I(I(89I0'79:7I(<9I(89;57I(=IC.(<44758I(6::6886&78I(I)I(58;95%I/'8I1(I2(I'8I6*>879I(5I(6=879<9598&I/'9I(58DI(764<;7I':1&I(75;7;8<:I/'7I(8;;768:I(9=56<49I(I(49I(8I1(7476I(;89;.956:69H'I1(;<<I.&83:I)I)9I':57H';::67;98H'<I-&9H'7;35I'67H':<8&<;I0'8:<9::I)9I)5:;98I,I(4;7I':85917I,84;I(G'88885D;788I,985;I)86I(97II1*&I1'I(5H'7345I'<9:;
@simulated.97
ACGGTAGGTTCTGGTAACTCATCCGTTACGTGAATACAATGAGGTCGACGATCAATTCTCTGGCGGTACGTGGGCAGTTTACATTATACAGATTGTATTACGGAAGCTGTTCCTCTAGATCTTATTAAATAATAGCCAACAAACCGTTGTCGGTTCCGCGCTTGAAATGCGCGCGCCGTGCGTACGATCATGTGCATGCCCGAATAGCCGACCCGGTTCATGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGAGGAACATCTATGCCGCCGACGGGCCCATGAATCTCGAGGCTTCCTTTGTAGTGGTTGTGCAACGCACATGCAATCATCAATTACATTCATCATAATCTCCCGCGAAGACGCATGAGCTTCGGCAAACTCGTAGTCGACCGCGCGCC
+
87H'4:I*H'68I(8I(;87::I,5I(:8969I(85:I(33=I)597:66<2:H'I(5314F'7I)98578I/'865I1(887F'89866:4I(724I(56H'I(9568G'H'=8778869I(2I'I2(8I(4:7G'I'7I0'I(8I(8;6I(I(H'83;2I)5I.&784;6849G'&64329?=7977644;258:<I-&9I(95:H'89I1(E&H'6/:675:553I+568:I(:5I';8I(;E&74I*D&<G'8H'893894I)I(>868495?G':I(57/I-&I-&725H'848659I(4I)I'I/'8637;I)I(7396I(637767574I(65:C>I(I(457I*3579=:I*6:6I/'2:9H'657>;365762I(;I(7I.&858559D3+57I(9:52<I,
@simulated.98
ACTCATTTGTATGCCGGCAAGCAGCCGTATCAACGTAATCGCATAAAAAGGCAGGCATCTAATTATATTGCATGCATTGTTGTGTCGCTTCCTACCTTCGGTCACTGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCACTTGAAATGTTCCCGAGGTGACTCCATATGCTCCTTAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTCGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTGCCGGATTTCTGAGTGAAAAGAAAGCCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACAGTACGATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTAC
+
98977I2(48867I(I(;F'5588I'4785<G';89I(;7<598II1*&I)78I(49947G'I(>9=I+9867C18I)4F&58<6;36I(I(79I(G'8I)76=9726797I(5585I(7<?:;4;>787I(877787F'49I(I(716I(;869:4574;785H'31H';G'6<I'5I3(46I(I/'25I,51;(4H':0::6=8I,I(I6)50I1(<7:I:+&9I(I)I(G'5<:779;89I(6(559G'3I(:I(7I(<I-&95I*I(;4:;67I':9/89783I,9I(I(4I.&6779893I<+&7I/'9II9.)&6574804::796I)I(:8I):58I/'44647377935(6958I(6;7:<7I1(4I)27;56;7I(7I(974I'69==II1*&7I7*&:88G'556I.&I);991;86
@simulated.99
AGTGTTTCATGGACAATCACGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGCAACCCAACCTAGTGGATCGATTACGGGATAGCCCCCTGCCTTAGCTGCGAATCTCAGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCCCTAAGACAAGGCATACGCTGGTCAATGGATTCGAATGCAATGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATAGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTGTTGAATTTCACGATCGAC
+
&7<5I0'88;H'38I'6:8474I(H'I(99I)67I'I';5;8AI(;9<I'4594=6I(I'I(;2<I)496:;85G'E&H'94I0'658I8*&8I(I2(I)I(889>F&:657<I(78I-&>;5<II2*&;8I(I*8787239F'5:5@28776H'>;5I0'46I-&I,&585I)5D&:7:588:I'I0'<I(H':6=67D893I:+&7I'::2I(H'35>:5379I,66I)<I'5I*8=G'998I'1894726<3H';>H';:<879;416;<8I(47977H'9I'8I(574I(9I0'994:;<;9I1(8I/'G'398I)I(::778I)8I/'4:34566:@I(3I'8I'I.&0<:78544%5
@simulated.100
CATGCAACCGTAGATTATCCTACGCCGCGATGACAGTAAGTCCATTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCTATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTCGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTGTGCGCGTTCTGCATGGACTAATGCGACTAAGGGATCCAGCCGAGAATTTGACGTGACACCCGGCTATCTCGACAGGGTTTGCTAGGCCATTTTTGCGACACACCCGAATCCTCCTATCCCAAGATGAT
+
6:<54I)I(94588I)53G'9358F'67;42>35;68G';8I(:I,26I(7:4I(6:9I'574974687F'85<>:784862E&;5;595<865I0'6I)I(98/9I.&<::I*II=0*'<67I)5:2I(95I(76I(855<827:I(8)557189:I'5I/'94I-&8688784I+549<37:I2(6:'<48I0'9:;78;39I(I)8I)78569I*67;774I1(8:6I'I)7I0'8:=6I/';;I(:67I8*&I(86I'5;6879:I?-'=7I'E&I)8I'8:I)5:89897;8I(05<65<I)5:9I(::63::<I)I-&98H'26I(799I(I/'587652386I0'I'C:7<7864596I1'I-&9::5I'I(:II2*&78;;9787I0'3I(3I(6I(76:I.&I'27757:
@simulated.101
TTACTTACCGCGCGACGCAGTCAATTACTCATGCATTTGGATAAAGCAATATAGGCATGAAAGTCTCGCATACATTACCGGCACGATCATTTTTTCTCGTGACCATTCAGCTGATTGAAGTTCTCGCACACTCCGAATTTCCATGTTGTCACCGGGAGAGACGTACGATCTAGCACTGGCGCAACCATAAACTCGTTCAATCTAGCTGGAGTTTCAATTTAGAAATACATCTGCGGGTAGGCAACCCAAGGTGTTTGTGGTTAATCATCCGATTACGAGCGTTAGCTTCCGCAGCTTTTAAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGA
+
G'47F&0I,67@47=5::7843E&I(3872;8769I.&I(89I-&65I)9836I(84.8I/'8;<78::7;467I(8E&I';74861;7II9.)&479688;I'5I)5=593<7I);I';I(<674988607I(;I)I/'I'79;G'3:57I(I2(1285>528585738;:8839:I*7=6I(I(79I-&:752H'8I':66<7:7I(76I.&8I'I/'7>I.&4:97788;>I-&47I(9I'I.&I,I'97I-&95I'I(I(9578I(=8I':774637G'888I'I)72738I>,'I/'I';76I(;I(97I:+&H'7I(899I)744=;;4I(88I(6;4>I)595786I9*&6G'88I(28H':I.&:3
@simulated.102
TTACCCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACGACTTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGACAGACATAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGGAGCGACTAGATTTTGTGGCAAATCGTTATCTAGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTAGATTCGGGGTGTTTCTTTGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGAAGTCCTTTGGTGCTATGTCCCCTAACTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAATCACTCTTCTAG
+
I(9I1(4I'47I);78I'865595=I*?886:I(7593I'9:864<653:6)8&D&5I(I)H'I*6;I(I(567:8I(9I'I(7I-&82;78;78<657537:6I(79I(7I(88:3&:6<5:910I(<I'5II1)&645I'6;;67643I0'I'8:48949I)6;H';<5449<I)6<?=88?969IE/(73I'9I0'7:'I(5686&873897H'8::322I(8>;6I(<16:<98763798I':34E&:=7:3>2:62H'8I(49:5:66666-78H':I7*&05I/';I.&I7*6:G'9::I0'I(<659874I)68I(I'3I<+&524969I(98I)I0'I'3<759678I9*&;I*8I4)4I0';86:I':91988;;<;876I7*&=3IE/(;73@78I(4297
@simulated.103
GATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTATGCGTATGCTGTCCAGGTACCTAGCTACTAGACGATGCAAACAACCGAATGTAGCCAAGATTCCAAGGCAAGTGTATCACGCGATTCACTGGCTGTCGGCTGCTCGTTGTATTCATTAGGGTAAGTCATACAACTAATATTCACTTTAAATTGACTAACCGGGCCACAGAAGGGTTAGCCCCCGTGAGCACGAGACAACTCAGATAGACAAGCCTCACGCGACCACCCGTGGGTAGAACGACTTTTGACGTTAATCTTAAAGAAAAGGCTTCGTACCGTCTGTGTTGCGTAGATTAGGGCTAG
+
595I(61I0'5I)7:II1)&:7;5566375I*7;87729E&:3I(2448883H'I.&56779<57I'355II2*&6I(7I)68;:'42;47=38I(5G':7I'544775:55;596=68<I0'9I(G'6I*86?;5I)I'5:I(I(G'I*3I()4373=:;69786F';63<I)57857G':9;8575I(488I(9:H'9I2(4I'>396596I(64I(;9I(89<I-&I/'I)64:2I'H'I/'I)8789I(I1(H'68IH0)%857689=5)51:5I(566637;97:7I(9F'49966426I)8I0'88I0'574F&'3=:I=,';927G'E&<5I)I-&6I<,&I(6I'4967I(8486862I'8;82766I'6I.&.57A
@simulated.104
TATTATCCCATTCAGTATGTATTCAATCTAGGTTAGCAGATGCCTAGCAGGGTCTTGACGGTAATAATGCGTGGTTCAAAGGACTTACGGGGAACGTGCACGACTCACCACAAAAATTTACCGTCACAGGTGCGAACTCATAATCCGACACGCTCTGGATCCTATCGGATGGGACCTTTAGAATGTTCCGTTTCCCGTCAACTTGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGAGCATGCTGGCCATCCGTATTTAACATAGTTATTAGCCCATGT
+
72I):3I.&4I*21>956249I)4H'75:5H'I(:5;43667G'889:=I.'27I(564I):I'9F&7594>I+I(8I0'I)62I(3;I?-'I(55687528:27<7I(44IG0)%I.'9I(397675H'5987G';:987G'9I)&6:9776854I(77G'8<67E&49I0'9I'I1(77I(:7I(I(1I/'I/'758I(<I(7878E&?7I'47:7088565I'I.&7I/'=48;H'I(7;99;57>5733;899474::I)8I(887I2(4957I*8=6E&659E&4I(I(655H'577;52983=8?I;+&;9E&BI(897965:5I'H'87H''=9I7*I)9:;<7F&9I*97I0'2467
@simulated.105
AGCGATCGTCAAGGGTACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCATACAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAAGCGCCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTTCGCAAAATCCGTGTTCTAAGGCGTTAAAGCAAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAACGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGG
+
5;8;406649I'I0'851I.&657H'I(:I)6::I(78A79:2:G'6I.'9I(2429I'76I(8797&?I.'456978H'7I(66849I-&I';2;I(798857I0'377I)I(7467:F&9557I.';5>8I'94F&7:II1*&I/'I'8I'5427H'4886H'4>::7796II0)&4657I(3927G':<:I8*&5I(684I*95I'I(74I(I/';6I/'667I1(I)1I(II1*&=9858I(8G'I)7:I(85I(67I(53184I-&:3I(6;:<4654357I*4I.'78:I(>I;+&87:35I'2;I(I'8;I(G'968:825F':==I(I()5;:7798;658:I(4H'5770I'979I(4I-&I(I'7587I)1I'47896I'6936<I(750:I)<885476F&
@simulated.106
GATCACCAGGCGGTTGCTTTGCGCACGGCAACTACGCGTTCATACTATCAGTTAGATCGATTTCAGTGTGAACGCAATCGACTCATACGCTCCAATATTATGACCGCTACTATAACACGGTCGGCTGTTAATTCGAACGTTTTCATGGCTCCGTGTTTCAGCGGCCCTTGTCGACTACGGAGCGCTCAAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTATAACAAATGATCGGGTGTATAGGGATACACGTTATAGGGATCGTGTCGCACTGACCGCTGATCCCTGGCGAATGATTATCGGCGATG
+
75296F&=I'7F'G'76I.&7984:;F&=I)7<48566I'8<698=<5738E&8:86<67I1'3386=8:I'67;I(9'@9465464<876I)F&9:I);8=4I':883213<I(885I(7:I(:7:I(F'I)6:I(>9I8*&71=I):7H'487I0'8868I(I0'I(4::<95583I'8684:86I(69I(I-&I(7I1(795I(62<:872H'I+F'48I(II0)&5757I(7:E&I.&I*I(::2458I-&9862I(89745:<I)4096857;4927;988I(857877I.&I)4I7*7@I(9I.'34895I/'987493I.';85872:I(;:7I0'678:7;69:<;684%I)885855I/';H'7AI'7;6F'?77I(4656:
@simulated.107
TTGCTCGATTAATTGGTATTCGTTTGTGATTCCGGCCTGAGACTCGGGAGGATGGTGTTATTTTGTCTACGGTCTACCACTTGATCTAGAAGCTCCGCCTTTTGCGGACCTCAGGTTTAAAAGCTGCGGAAGCTAACGCTCGTAATCGGATGATTAACCACAAACACCTTTGGGTTGCCTACCCGCAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGAAATTCGGAGTGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGA
+
I'79479:I(I(I(I*7:I(:6I.&174:I)I(I'I)::??4'89I.'5I'96H'73I(<I<,'<23684I'6:2<I(6<I(8<55775I)965H'9I(I?-'94H'>G'5<6G'I.'I>,'>9;7:H'I'??>H'7:68:57I'<4I(9877I(I)I(97I/'73I)I-&I2(I(6I(88I2(867797;4<I.&8;I-&I(8I/'8;E&;;77;=3I(8I)7938I.&67I(G'6:9G':46:433746?87/5808:4:I0'E&=4<7F'9::DI/'H'7I(5873697948I)<I(0G'5?69;53I(5I'67;7875II:.)&925849:8I)I(6I)8432:1785824I1(0=:5I)77::I*88I0':3E&I-&189854577G'I'385386:745::5I/'4I(:8I)8;7<I(476878:
@simulated.108
GTTTCCCGTCAACTTGCGCAACGTTAGAGATCATAGGAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCTACTACTAGGTGCGTCATACCCAGATGAACGCTGTCAAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTACTACACCCGGGCAGTACTGGATCATTTAAGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGT
+
:I2(I-&696I'=H'79:7G'77I)99;<96855;I(I,1I/'7994I'I)86<87;696797675887;93D3I(756I1(9548I(177G'784D&3I(I'7:7I(2665878:4477I@-'78I)5I(686:7476I'I(3:I*43I:+&E&98<22H'=I'5@I.&77:G'677I)I1'45I/':6<I(;797I(07;7I(:'8174942H'895;;6;;3I0'558;8I(746;646I?-'948I)3I)<76I.&75>594H'I(75888869:2;87555I1(4I)8:=I)3I>,'8631:8<4=H'I(65F'H':;'7381I.'I-&1464837I)90C6I.&I(G'<4I(I+=8197:4:8I/'654:I'I-&52I/'H'I2(4;I)I(I(I'8=9796I(:
@simulated.109
TTCAATCTAGACTGGAGTTCAATTTAGAAATACATCTGCGGGTAGCAACCCAAAGGTGTTTGTGGTTAATCATCCGATTACGAGCGTTAGACTTCCGCAGCTTTTAAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCGATCCTCCCGATCTCAGGCCGGAATCACAAACGAATACCAATTAATCGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTTAGGCACTGAGAGGCTTGTCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTCATGTCA
+
F&6I(8<257&88I);7I,4I(I.&49I0'759:8946:I.&65D9I(I0'I.&H'2<I0'8;I(I(I(9679H'75I(=756:37I'78&2G'I'=6=99I=,'I2(G';>7I(7I(<7I=,'H'6I(65;I(;:37685I)7:E&8826I):64653I;+&8I)42I(*87I(7I1(4352>7:I'I(F'I'9994I.&:5I'34I(I'I(I'816954I(69I'I*I3(65<I8*&883564I)I0'5I(6I'I(644I(7I1(5I)7;<68857I'9I(:)I0'6878I';777I(I-&:8I/'8I)9H'7;73888I-&6IC.(F'39I?-'398:8I'9:;4:8363193:36:8I(<72:I-&I-&I(;476>6:G'<69737I(I'<9I*9775A61
@simulated.110
TGGGTAATCCTAGCCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGACACGGAACATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGGCCCGGACGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCACGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATAGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGC
+
7I.&'I'/H'7:=H'88G'I-&I(;7:8I9*&:85466::568I)88375<54?<676I(6934I)I(6;I(9:5G'F'E&6=478:I(H'6;55778483I'889595I=,'4@3I'7I)8>I)I0'H'5&64G'46I.&678378<;6I-&I(9I(3H':4;573;9;I-&2I(69479I(I(979H'I2(7I2(5::6817:I/'6I)718H'6I(=I'7:(;9:F&:78684574:8;5I(49I(59559;779I(659I)65I*8I)6F'<;I-&8647<84%:I(I(=89E&8I:+&782/69985F'H'9I0'I);93939>I(3I(589I.'I5)8<I0'77=G':7947954;H'48=9;59I4)I)98IG0)%7
@simulated.111
CTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCTACGCCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTGTGCGCGTTCTGCATGGACTAATGCGACTAAGGGATCAGCCGAGAATTTGACGTGACACCCGGCC
+
57;:56I.'44969967=:5:74331I9*&6945;7:I,=54>H'I0'I1'<I'G'5:56I'E&8;429F&47D8:A8I(4683652<:;6I(5=I(4I.&78H'<35I+7:5H'6398;5498E&8<4:977;:55I';:9763:6:=I0'7I)I(:485I-&93;H'II8-(%=;5I(465H'97I':3I(94878496G'8<798998H':I0':7I0'3:56672I':68:75:I/'889:6I/'18899837H'H'5I);65<?I'352797I0'796I*H'2I2(688@I/'79I(;38IC.(H'=8I(69;1768I8*&:5I(G'I(8I+35I(45:766583I(4?79;7I(732I(29/;676H'I.&38D99I'44<I(I,&98:97875:I.'I(I)
@simulated.112
TTTAAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCTCAGGCCGGAATCACAAACGAATACCAATTAATCGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTCATGTCATTCAGCTAAACTTGGTTTTATAGCGGTTCTCCGAAAAGAGCAAACTATTCCGAGGCGTGACCGGCAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCG
+
I0'I3(I)5:2I(7I'78I9*&F'9E&86<I(7:27988I(25I)7:85I(5:<;6;I=,':I(=8G'5;I(2I1'>;64:95G'I)I(H'497;I/'83I)9;I(I(I)I(7<56:8I':9I(G'I/'737IE/(265776I'I/'=G'5I+I(;75F'5I0'5G'698:9=95I';I(9I.':797I(544:I(I0'69I.&7I)AI(:777976I/'6II1)&I)73I6)68866I(4566:62979579595<F'6>9:I-&I2(I(99;7824G'4<9757I(F'6:I,5;;8568I(3348<I/'9I)I)I;+&9=998G'I(59I(:I=,'468;I2(748I(I(27I(1'466F'I)6I7*7H'I'8G'94662659/96I(95I.'86I(8I'7I(I)93884I)796
@simulated.113
AGAGCGTGTGGATTATGAGTTCGCACCTGTGACGGTAAATTTTTGTGGTGAGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAGACCCTGCTACGGCATCTGCTAACCTAGATTGAATACATACTGAATGGGATAATATCGTATTAGCGAGAAACTAAAGAAGGGCCCGCAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAAGACGCCCACGGTGTAACGCGTATTACCCACCGGTGTATGTGACTCTCCTATATGGTAGCGACCGCGCGGAGGAAAAGCCGGACTCCTTGGAAGCGAAGTTGCACCCCTATACCAGCCTCACGGCCTGATGAATTCAGAAAAAGCCCAGCTTTAGGGGTGCCAGATCTTAGTGTCCGGCGGATATGCGAGAGTATTGGTAC
+
394589687I):H'6;998I'7;87H'858<57I(9I.&II5,'71I(:<::>;4345775I)I<,'7;H':3I(I.&7I(I(98744I)6I':E&496D4=I-&;:871(I)96=729;9I(I(457;I'8I(:0>=43;>6G'6I/'09I*9>6<78;I)55877<I1(?4I/'4I(I.'I/'847I(7<672:I(I'7I(:>I(<69I'68I(3I(6I(I(78I0'G'I(5672I/'88H'7:3G'5346;9H'4I0';G'H'9466::79(5526H'59;97I)67;4@5I*679;F'3I(I?-'5H'I(486I(I'H'I(569I)6I(585I:+&*767I(;6I(7>9:I(I)7644:I)I'992II0)&7I.'467I1(<IB.(66I)2:427I(4667:I(I(3I(6735945;8368=H'H'85:
@simulated.114
TATGTCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAACACAGCCCACACGGTTATGGACGCTGAGCCTAACATTAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTGAAGTATGCAGATAATTGGCCCGGTCGCGCCATAAGAAGCGGGACGTCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCGACCTATTGCTGAGGAGAGGTGCGTAACCGTCAGTCTTCCAAATATCCCGTGGTCAATAGTATGCAGCTGTGGTACATTCTGGTGGCTGGATTTGTACTTGAAGACTACGAAGGATCATCCGGCCCCCGCTCAAAA
+
=59;<79I(896594;<:7:I:+&78:4I(I.&I(76F'779G'=I(I.&627;F'57866I1(6<48I)I'9:I)7858:876I)8I*89G'9756<3I2(I(=9H'68:::I(7I)I(68:7>6I(876<3H'52I'=;4975:978H'I(I(I.&F&7;945I(:3I(4I(78I1(739&G'7I'576828848:8I(776I1'H'416:I(757I(I(75I/'882I(863<6/:I(>56I*476785=77224935;;55H'77I(95<I(776259::98G'49::H'I(78I'619;%:I):7E&5344;I(;99I'75;94I*I):(5865<I(I)I,&9?9I.&69I(6:I'9:5:3578456;6:I)459=I)74I(6I(36I(1I6)7663I'8H'79:8041I(I(99789H'I(II4+';645I7*&
@simulated.115
TTTAAGGCTAATTGACTGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAATAGTGGTGGAACAGTGCGCGCGAAGGGAGGCTCCACCCGGTAGTGTCGATCAATGTGGTGCCCGAGTGTTTCATGGACAATCACGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGCAACCCAACCTAGTGGATCGATTACGGGATAGCCCCCTGCCTTTAGCTGCGAATCTCAGTATGGCGCGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCC
+
I1(I(I)7:I(I'55%4>3887;I.&=857I(I0'59I.&I(I/'74I(I(I(H'=64686H'7:I'I)8587G'8889:H'6I)3I(F&:49I)2<6I(94I(?I)I(6I(94=975597;I)69779929I(;675I(6I(I'93476<7569<H'I0'6I'39F'2I0'I(369:;9799;2G'5;9I'66I.&88649I.'430G':>I(;97595I)F'I(89F':9I(I)8<98;I(965I(688>85H'I*F'7;5I'19765;6I'I(H'78I/'467I:+&:I(I.&I(I):499H'96?68I*56I0':27<II3+'76E&I1'6>4779<E&58=795988E&4<5I*49I.&I.&5:6I(9I(6537:38I(I0'8I(G'760569685I/'
@simulated.116
TATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGGCAAACAACACTAAGTGTAACGGAGGTGGTACATAAGCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGGCTCACTCCCCTTGAGACGGCTATGCGTTGTATTCCACCCCGAGACCTTGTCCCTTGCCACAGTATGATCGAGAATGACTAACTGGGCCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTACGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCC
+
71>:I1(G'6619669=8F':06>:55679I/'9786857I.'6I'980:I(I(I(79I<,'489I)I:+&6I4)<I)7>71I(:>;8I(9I*:I(4I(8<:57H'A?<46I(9>5:;544I*I'I/'I':F'14G'I(88518343I(775795398;:=94:I(8778I(38I/'33;5;<I@-'I(;57;5I'94:<5<7I)4:8H'I(4I:+&35=8I(I'56I0'I'=I(6775;;59835772H';6384I(:6I-&I.&I(<55I<,'89<7I(:I(G'I)/F'926I';756I'G'76694:57:?5I)I(88'8I(I0'6I(73;I(5;4:8I'46H'I)675I(773F&59824I';I'<I(868I'85:I'6;9:535:G'6528I<,'68H'
@simulated.117
CCAGAACGATAAGCCACGTCGCTGGCTTCACGCTGTCCTGTCGATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGGATCTTATGTCTTCAATTTGATCTGTGCTTTCCACGGGACAACCCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCCGCTATTAAAAAGAACTGGGTGATTTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATTTCATTGACATAGATGAGGCTTAACTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTCGGAGAACC
+
I)9:I(697:I(=I(7(76285:I(8I(8>858=56I'5277(52I0':I,&8I(6G'H'I(2;3I(7I(:364875949<<8I(47.54I(I(I)5I3(884I(:976:I(4I(I-&8867668;7I0'I)6;I.'97I'I<,&I(:5:86<:62:I'H'I(I)3<88852;89:8I(589I1(4<<5;754I.&II3*&0678?69:4F';65656:25I(;?7H'7=8:7H'55G';49I(I.':9I(I(7I'596I/'4:I.&H'I*I(I(:7I=,'745<I(II1)&3I(35I/'63/I@-'I)9:6I'9I)IB.(5:;I(95@0<I(F':G';I)9<I5);9I(87;;9366476H'4G'I)<I5):E&I)8<88I(87I(I*28;I/'8683I?-'9I(96I(I(
@simulated.118
CTAATTATATTGCATGGCATTGTGTGTCGCTTCCTACCTTCGGTCACTAGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCACTTGAAATGTTCCCGAGGGTGATCCATATGCTCCCTTAAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAAGCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGTGCATATCGATGTACATCGCCGATAAT
+
66H'I'3:=E&:;66I(:5I+9:55;8/95I(I(65I)I(6I*97896%74945I)8;99I(6777887::2=I)976813I)66I(I):33I'4;;8597:86988I(84I(4I)96I(CI2(5:I(I1(21I0'9?16I)63<5636I0'H'I=,'<2I0'478IF/)<I'I(I(I(@577674>7I'6:<9I(4I(8I(:I(4I.'65F'D&:;8964I);753=5<9I0'9I)G'3I.&6466777I8*&7I4)0II6,'5:43=5896782I(I)>8D&<76I.':;97479:;=79899I(7/5697I.&6I(888:7=8I)8I'<63I(;294II3+'7I;+&367F&765I/'I'=86946<;7;88I(4I<+&I/'3;16<:4I)3791I'97I.&8;:I,94==;765;8:2C880:47I(818H'5
@simulated.119
TAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTTATGACAGGACAGCGTGAAGCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCTATTCTAGTTTCAAAAGTTAGGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGT
+
:H'974I1':I(I(I(;8>;5G'3:<:9<8;<:3<1I(6F'696H'I(I(8I)7I.&8I-&A46695H'8:;978>7H'8H':;52794I(6H'7825I'99I0';:93I)7736I*67:4H'9I;+&15696I(49398863349:32I)73692I2(5>;<I)58I(94I(877;;I)8I(I'34677I)386I(=7:I)<86<67II1)&:6I>,'=:;;:<9<58;6'6I*:972I1(;I=,'3I(4I8*&5<>9=665I'I0'I(/;I(6924:7I;+&:H'I)69H'6184797I)I/'=28I)76I<+&I.&4I-&06I8*&6I(95636928969:I(6I(<;64798:3:H';:7I(;6;5655386799I'65:8H'633976I'56=55:8577H'14I.';H'67II1)&:6495;
@simulated.120
TTTTAAACCTGAGGTCCGCAAAAGGCGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCTCAGGCCGGAATCACAAACGAATACCAATTAATCGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGACTTCTTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGCTAAACTTGGTTTTACTAGCGGTTCTCCGAAAAGAGCAAACTATTCCGAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGA
+
I=,'I.&I'94:I(6F'58I8*&I):G'459F&4531::6H'88I(8889H'96;589I<,'3G':<I(99I(5I0':94:4:9E&I(H'I)767<I4)77I(63H'I(I'I(649986I*91I(I(I1'<;5I9+&58575>F'I/'5I*;I(I(:4:I)=I.'8I(165;3825I(:I'5I0'56:9I)868:H'I3(88I0'6I(5I(84984<4I-&7II0)&I(4:I=,':6;88H'7896;<:8751670:77I'69<7I0'I0'I'456>:88I(3<9884G'I(89I/';5798:6H':9679I0'5I'I(I;+&7&9957I)G'8;I(8I7*&8457I.&971I'I(:1I)647=I(I(5I;+&5I'I(7I)6588549<671I)6;>
@simulated.121
GCGCAACGTTAGAGATCATAGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGAGCATGCTGGCCATCCTATTTTAACATAGTTATTAGCCCATGTTCGACCGGGTACCCTGTGGAGAGCCTCTATTCACTACTAGGTGCGTCATACCCAGATGAACGCTGTCAAAATATCCGCCATGCCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGACCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTAAGGCTAATTGATGCATACTCCCGTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTG
+
9734I(17I(88;8:7:797DI1';I0'8787I(I'9>99587:7869<237;;:77I'6I(568I-&5515I(688I(5:9G'8I'I):=6F&47133=354786I8*&88G'4I(64::239;I'I(89I'<;I<,&I';7058I)6I(3:I0':6>I(476I(I.&89I1(86<I*7489H'556=H'8==644:;I(9653257:7I0'937;:H'719;283I;+&;45I)5I(893I0'9275>9I)I(986<::5;>::75<55I.&4I'378I(5&I8*&6566;>58<G'I(:4I(I(785<75I/'I/'28119:5I(67H'9I+I(H':6E&I(;159=;61&8I2((1579I+I-&59I2(I)I0'86I'I)I)H';:57
@simulated.122
GTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAATTCGGAGTGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTCATGCCTATATTGACTTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACAGTAAACCCCGCCACACAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTATCAGCGTACCACAGGGATTCCCAACTTGACTGTGAATAACAGACAGGTCCAATTGGCGGGTTACTGGCGCGAACATC
+
<::I1(04I.&I'2I/'65H'9;86484I)6I*9864I1(66F'I(7;4I(45884:66477;:8519965;I2(I(96;2I'994I(I+G'8I(5398858559I(9I(7I(497:<9;H'=I)<786697II9.)&395=8868I)I'6I(79345784777:I,0:93I(4664I':(1I.'38I(I1(968809:<5I'H'698692665735<I.&8I(37I)17;5I(73:655:I(1H'37I*681729;I7*I9*&8H'90554887:I';7I0'ID.(:::88=I1(I)8H'I(I(.5<96:5:I-&I';459I/'838I)I(F&I)6988F'9354;I)8I,69:64556<I(676I0'8I)I-&I'9I(:438@81I'7I'589368I(8I(I(I)I(<I/'I'795I(:146I)8;97
@simulated.123
ATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACACGGAGCCATGAAAACGTTCGAATTAACAGCCGACCGTGTTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTGCGTTCACACTGAAATCGATCTAACTGATAGTATGAACGCGTAGTGCCGTGCGC
+
4I'88I(1I1(49:4:1I*;8;:8369:6;7<6I/'888I)758:575I/'<7:671I/'4<7;<I.&7I(68I<,'2I'I/'89:648I(9865798825:A;74:I)93=:8:;I(6679I/'59:877I)H'I2(I'89I)7;58II2*&I(09I(I)I)=9<@;9:H'956I2(6I(I1(I*77I(=:6895>H'444253:68I(I/'I(3:3:I0'680I(88I)656I>,'=6I)95I(I(I(567I)49H'988I'>66415;9I)68:4I'42I(G'9635347977765I'889I(=7:44<;I2(3994866I(9:;:?4773<7I'408463:C5G'5:7:;8
@simulated.124
CGGGGGGTCTGGTACGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTGTGCGCGTTCTGCATGGACTAATGCGACTAAGGGATCCAGCCGAGAATTTGACGTGACACCCGGCCTATCTCGACAGGGTTTGCTAGGCCATTTTTGCGACACACCCGAATCCTCCTATCCCAAGATGATTTTGTGCGTCCAGATTATAGATCGGCATTGTCGAAAATTCCTTAATAAGCGATTGCCAGAAGTGTAT
+
3II=0*&489I(4'7:I(:5I)=7I(:84:<359I(36<66695G'<I1(;5I0'895::?7I(;9424<8I,;;;99I/'946;4;98I(I(<I'519;5I(7:66.2I1'470H'I(6I3(68:6I.'7<I(268I>,'I(47I(95:3;49I:+&84I(I)G';E&>7I(9:9628;65I(73573:I)965I(7785358I*I1(4;I(;8H'<37G'I0'529=:68=8I/'I(H'5555778695I.'I.&/769G'I)9II1*&<4154;64I2(8H'8I(:I)577I/'I(6596@I=,'7=::53I(789H'45:8942I,=4I(9456I=,'I'I(I(I(=H'7769I(8I*96I)8589;3
@simulated.125
GGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTACAGGCGAGGCATCGGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCGTGTATACGTCGGCTTCATGCACTAGCATGGTTTTATAGACATCCAGCCACAGTGCAACCGATCGTACGCAGCTAATGCCAGCCTAAACACGCTTGACCCCGCTTCTAGTCAGGTTGCTGACCTGGTGCCTAGTCGACCCGCTACACCCGCCGCTAGGGATTAAAGGCACTCAGGGCCATTGAGGGACCGTAGCTGACTATAAGTCGTCGGTCGCTCGCATATCTAGACACCTACCCTGAAGGGCTATC
+
I.&7746:6;I.&I'=8I(G'2H'797863@:73I@-'G'244I(4I)=I1(7I4)I/'8H'3I,I(7361I'8:7I(973I'36I(3=5?:9I(5I(I:+&8I)I(45I.'6464F'95I(G'5I(6:I(:845:*:6I'88;H'8697I:+&88I):I(:7I(71449<9:I(I:+&:=4:34<=6+8<96639>:7I'5F'9259384;?:74:I'I;+&77899959I(4;G'5::=438I,I):55(86>4676764I)98I,72I(4I0'=9=85G'79I:+&68I)87:496;I(I*97874I)=G'3:I(6873678I0'899;78I-&5I(8558I-&5I(I-&G'69&9?8I.&I)8I(7;I.&8I(746:96:16576I)6<5638F'87574;3:650984:<576I'/9I0'<8H'I.&=364;
@simulated.126
TCGACCACGGTTGTCAAGTACCTCACTCCGAACTTCGCGATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAGATCAGGTGTACCTGGAGTAGAAAAATAGGATCCTCAAGCACTATGATCAGGTGATATTTGCTAATAACCCAATGTCGCCCCTCCATGAAGCCGCGCACCAGCTCCCTACAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGGGACCTCAATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCCTTCATTTTTTGTAGCCCCATCACCAGCGCAGTACTATCGTTGTAAAGATCTTGCACGTAGACTACTGGCCTAGCCCTAATCTA
+
33;5H'68I'H'788H'633I(81=5:I':I*:H'&9<':I(877I(83<=;:3<I(7=78ID.(9:I(96:698>9F&5I)6I.&I4)<7565G'63;7G'8I(;1467II4+':9I(9;E&1:H'7=86;5876472I(>5:49I/';69I(3I'I0'I(87;66I;+&6I)=6=I):H';<189I)9652I1(777I)6I1'<48I)5I(:84887774;34I(8I0'I(<9;I1(I'93H';9I)I'I'I9*&9I(89I)I/'I)87<5I(>27655F'45G'61697I(706I1(I(=8II7-(%4484I8*&622:I)<92567;4;1;6466I'2:I-&=757E&941991=77695;<I)H';68I3(9I(7878
@simulated.127
TACTATAACACGGTCGGCTGTTAATTCGAACGTTTTCATGGCTCCGTGTTTCAGCGGCCTTGTCGTACTACGGAGTCGCTCAAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGATCGGGTGTATAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATCCCTCGGCGAATGATTATCGGCGATGTACATCGATATGCACCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTCGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTA
+
548676I(566I(;:I(7:7I(G'I'76D&66I<+&667I(39I(772I.&5:58I(I,I(7;67(67875I(>4%;?1:5I(99I)I/'H'8I0':36I'6976888I)I(I(:6I(II3+&6:78I*<7G'I.'I'I(6899<8I-&49;3G'79:17:4G'=7:875857<81983:I':/7033I.&I*2I9*&;8I(:I1(;3:73I0'6;439<I0'976>4;7F'644I.'875<:7::7:/:80F&787648I0':-E&89I,7;:I)995I(7681956:0:7758848<9I,4<9I0'<8I(;;78I(8.2:6:<I.&I:+&:I'=6:72827;<4?I)I.&794I(798I8*&=II3+'638@I(5:7H'8H'75<;168E&7I.';61695I)85;
@simulated.128
GCGGCTCCAAGTGATCACCGACTAGCGGCAAACGCGACAGTTGACCAGTGCGAAGGCATTACCCACTCAGACGATTGAAGCTACCCCACCGGGAAACGGGATGTGCCAAGGTAGATGTAGAATGTGTCAAAAACTTGTGATAATCGGCGACGGGTGTTAACCTACTCCGCGATCACGGCCCCCGCACTATATCACGTACACTAAAGCGAACGCATTCTCGATGGCGTAATAGAGGCCACCTAACGTCCTTCAATGCGCACACATCCCGGTGCTGGACATTTAAAGGAGCGCTAGTCCCCGCGGGTGCCAAGTTATGCTTGTAAACCACTCGACGACGAGTAGGTTCGGCCCGTTTAACTCGACTCTCTCTGGTGGAGCCCG
+
4<I(64H'G'9831:83I(88984;2I(:I0'6797::77I'79I)667348I'I(4@E&6I.&7:;26:8:49I(3I):71;I<,&3H'I1(I-&;I-&445:9H'G'I)986838667I(7:48<2II1)&5I(>7983I'9AI'64<:I/'78H'D&I'609<I(3687:656I(II3+'47763791/95897'47<7I0'567I*3675I)87;;;;I*56:I):567I(I)8I(9I*97<I'H'4E&2:73::;=999I.&I)34=9I':49I.'I0'I(6466=884@I9+&87I2(40I'I(6I*93;6I(68I.&I(6;5;4469486879;I(I)'I)I/'5I0'I(:75;>3986@922I)<I(9;I/'6
@simulated.129
GCGCTGGTGATGGGGCTACAAAAAATGAAGGGCTCAACGTCAGTTATAATAGTCGAACGTACCAAATTGAGGTCCCCAAGGTTCATTGTAATTTCACAATTTACCTCTCGTCTCGCTAAGTTGACGGGATTGTAGGAGCTGGTGCGCGGCTTCATGGAGGGGCGACATTGGGTTATTAGCAAATATCACCTGATCATAGTGCTTGAGATCCTATTTTCTACTCCAGGTACACCTGATCTTTCCCATTGTTGAGTGACAGGCACCCCTATACCAGAGTCGTAAGCGAATGCAAGTTCGGAGTGAGGTACTTGACAACCGTGGTCGATAAGTCAACGGGCCGAGCCTTGTATCATGATAGGAAGCTCGGTCATTCAATTCCACCTATGCCCCAGCAAGGGCCCAGTTAGTCATTCTCGATCATACGTGTGGCAAGGGACAAG
+
395<6I)6645I=,'7768II8-(%86I(I1(4:7H'8'6867I(68I(9:9979I)615:I'I/'E&;0I'5I:+&I*I(G'97I'65I(I/';59I)I1(6I(::;4<8489485I(7F&2;8I,&6I(98:I+7988I(<84<8H'6I(8=2I(8I=,'9;448I(I-&I(9I)5A8I/'6;984I'598;79:379<<I(87567I(65IE/(33617I(5I'5994G'37639I1(I3(9I(4I'=:;9;978I(7<I:+&1939I(9;66874<I(;59I+:46I(4I)5H'47:69H'596I(264I(F'7=I):558;I(872I)8I-&I(894I(I(697687156;4G'H'788;F'891G'4I(I(I(4H'4=6;I>,'926H'I.&I.&97I)9=9>5I)5<7/597:5;6'9=7I(7I(I/'67I(=
@simulated.130
ACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACGTCGGCTTCATGCACTAGCATGGTTTATAGACATCCAGCCACAGTGCAAACCGATGTACGCAGCTAATGCCCAGCCTAAACACGCTTGACCCCGACTTCTAGTCAGGTTGCTGACCTGGTGCCTAGTACGACCCGCTACACCCGCCGCTAGGGATTAAAGGCATCAGGGCCATTGAGGGACCGTAGCTGACTAT
+
77;I(<I/'8I(57I(4:I/'757=3:6I,&I'72I(G'6I(:9646=:47:I8*&G'773I(3I'8I0'7I-&I4)6F&9I/'I'96;<I)246I'6;:G'75H'6<5877I);I(I7*&4H'C7<I1(6@9:I(76G'I)8I(;7I'47842:9G'6;4I(6685I6)76I)6I)5;I(:93:278<I(I<,&4:77564694594936;9=I(:I(?7518758:;9;;H'I6)87794:57I'8:H'88::15;I-&H'985=;5:;:5:8>I)65I/'8:H'6I.&8766:I):6I8*&;+6H'5875986H'I(:3668I)<G':4I(8689(664I.&858769I0'6I'64;5I2(7I)I.&I(3655:I0'I(3I)67I0'9G'6867696478;2
@simulated.131
CTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAGTATAGGTAGCACACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAGTTAGGGGACATAGCACCAAAGGACTTCGCTCGCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCCAAAGAAACACCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTA
+
4:I(7I(;565F'96I/'7:66I(4492I(43;6I(8I6)<86;7F&4775:5:=857:;5I'67977I0'73<9I(<5I(79H'98967H'5F'I)599:7H'5;8I)4:9I(:996:1II2*&:;I;+&4:@7?<7889<89G'1>97I0'6I;+&4F':I9*&:864569;I(I/'I'55I'3509:6I7*7G'G'26I)9;:;79<I(I/'=46I'98I=,'I0'6I/'8;I6*7I'=:676:27;676I(9H'965698674;I)749I)4:1:559:9:488I(8782I'<89888H';:6;<;489<I(43I2(8I(0<II1)&7:;47876;;G'8;;7873I)57H'59:5;7:G'I/':<578994I*:53IG0)%6G'4I*4
@simulated.132
AGTTCGTAAAACCCAAGTGCGTTTTGTCGACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGCTGCTACTGCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTAGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTAC
+
77I'787I8*&I1(I(847>5I7*&7.;52:75I/'53:9:789;6648I)6I(=:=I'7I(65=I.&8H':I'34I(677I)I'I(6;9I<+&I(99I.&H'I2(I)4I(I.'I0'I'I*6;;<:;9?2I+8E&35I*96I(G'<3;I(I/'3<8;834I:+&377F&>79:6355885F&26I.&789H';2574:8I(I(884829I'747885;76F'6I(I)6I)II1)&8<G'74.976I'I0'7I(I.':89G'55459I);7I(:I-&I2(I)34:588485I(&7I+76I)=5=<97:542=9I;+&65I'H'H'I)I';43?6;71:F'5I(H';8I(9H':97I)I(2:I*7I0'628:8I)=79871<
@simulated.133
GCTGGGGAAGATTCTGCCTCGAACATAGCCAGAAACGTCGCAATACTGGTACGTCAGCAGACTAGAGAATGAACACTCTAGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACTGGTACTGGTGGGTTAACTGGGCATGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCATGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATGAACGCGAGCTCCACGTGTTTTTCACCACCCACCTGGCATCACCCGTCTTATCTGAGTTCAGGACAGTGTCACTTTATAGGCGGACCCCTCAGCAGAACATGCATCGGCAAGCCTTGGGCGGGCGCCCGAGTAGCT
+
A67I<+&I(;8I)877I(4<<I'695%8H'96I2(9;8769I);5:9H'68(:37=749326;9719I(78I(4:574@&I)32<722I+I(94I(3;55;<:6:468I(7I(=456958I)948D4H'757:H'6I,&G'I(65I1(7:6I(69:=:I.&I1(54I(68I-&6G':845845;I(6865<G'8I)I(77665?I(9I);77I(I'527:78A85I)6759;9I'<6I(96;67:57I'8::94IG0)%<6I)5I.&;I(;I)777@1I.'3>5I(7=58865I(49I(766::8746=I0'457I':I(3I<,'55<7:;:I,99;75>68I(7I(8G'I(I/'5I.'<9I/'9:683=97
@simulated.134
TCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGACGCTCCGGCTTATCGTCCATCCGACCAGTAGGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCCAGAACGATAAGCCAGTCGCTGGCTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGATCTTATGTCTTCAATTTGATCTGTGCTTTCCACGGGACAACCCCTTGACGTATGTCTTCCAATTAATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCCGCTA
+
7567=89I;+&57IH0)%628689G'77;F'565I(6(4834H'I)6G'78=36H'53I*3:I'=8=8I/'46594H'46?=5989;438;6F&98::5I>,'4I(6596I(::;8I(63:7I0'6<H'8;46I(5I'796989:G'1H'=765<:66I(>19841I/'5I.'5I'6H'I(I)?67G'5I(:66457<8:09:8I(78657I(I)G':I+859I+:=675F'5I'I.'9688426>7I-&G'64I.':6I(I;+&I':5847=4397I(I(I(F'E&7:788669892I)856I/'4838=84;I1(II2*&:98:86::4G'7=5;855A7H'787I'714:7I(9<I(89;G'I4)68I'I'>F&:55I/'69I0'I(G'I(I(85I9+&79=9
@simulated.135
TGGTGGCTGGATTTGTACTTGAAGACTACGAAGGATCATCCGGCCCCCGCTCAAAATACCATCAGGCTTTCGGTCCGCTCTTAGGCAGAAGTTCGTAAAACCCAAGTGCGTTTTGCGACGCAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGCTGCTACTGCCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCGAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTACTCGAGCCCCTAGGAACCGGTTCGTAT
+
4I*8I'6:G':I-&=549I(4I(7878;;8E&H':8=66I(I(II1)&>877IA-(?4I)5469I+5I.&=I)9G'5::8I)8I'524I)9H'6<6I=,'I/'I(03797I;+&178886;I,747246;876=37H'5I(959I(0I)973I0'7I(4I)6=I(949H'I)H'66;I:+&I'7;I1(H'I.&I(8G'I.&I.&H'I.&:4557=37/I0'6I(66I(6<I(I(54:I(I3(8;;3:8;I=,':59E&98069555769I):8I1(84;I'694;674I(I(:28277I(5;;966>97I(4I(I)6I)IG0)%<7H';7;38:&H'I/':I'I-&8;9I(366;9I)59E&9I.&I2(I(5>:52:737I)5I)68I(8848=95'259:5I?-'7:I'I)I(I'I)88896
@simulated.136
GCTGCTACTGCCCAGGACAAGCAAGGCGTGGTTTCGTGTACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGTATTCATAGCTAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCTAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGATTGCATGTGCGTTGCACAACCACTACAAAGGAAGCCTCGAGATTCATGGGCCCGTCGGCGGCATAGATGTTCCTCGTCACCGCCGTTA
+
98<:679957I-&6I(97I(:8F'I'2:;I'I/'9297&:98I=,'5:7I'886=968::<;I(59I/'598H'7863777I(I)6864;4I(63;64<97<I(8I'I(3I'II2*&;&AG':4626<%I(I/'<I'I.&648I(;7898I'14I)6I/'I0'E&7>8175486H'7I(9%8I*979=567;6855I<,&65I'I(I(I(I)6;91948:9I'9I(I';7I':G'8;:I(I(57H';I,6775?I)66<77=9:3<I.&6I(5I(94664=<6713I)886I2(87=I(957784I)744I)I(=I)867H':46<7:4<@I(881-I(I(9:588I.&I'I)7I)509:74I(765I/'I.&397G'7H'685877;<I(I(6;9572I)8I'9G'8
@simulated.137
TAGGTTACCGCCGCTTTCAAACTCATTTGTATGCCGGCAACGCAGCCGTATCAACGTAATCGCATAAAAAGGCAGGCATCTAATTATATTGCATGGCATTGTGTGTCGCTTCCTACCTTCGGTCACTGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCACTTGAAATGTTCCCGAGGGTGATCCATATGCTCCCTTAAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAAGCCCCCCTATGATAGACATCCGGCGTTATGAACTGTACAGTACA
+
9;F&I(<E&;I(:5I.&5I/':953I0':8789I)I(2I'(:942I(76998I'8<8I*=6:198II1*&I(59I(49<18I(I'9:7I(7466I)65H'388966819I)I'83G'H'1I)558998977=I(7565I)84;6773;51:I(7:9362I(72H'I'8<7I(88859:54<9259I'=9F&6I*:8I(5I/':8G'I0'55I0'.:3;I(879;9:;I-&I(I;+&9=I-&69<I7*&<G'I(I(I(67::7829>I(8275I*;I(6I(7I)6I-&>6F'I)48;152I(74855;38I/'=I(I(7I-&<::9967I<,'5I2(:II=0*'39632=4;526:I*I':8I(95<I,6<747=9:4;:7
@simulated.138
AGACCGTGAACAATACGTGTACTTGGCCCATTACTTACAGTAATCATTTAAGACCCTTGCTATGAATCTTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTAGCGGGATCCGCACGATGTCTCCTAGTTTAGTCACGAAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTTAAGGGCTGGCCCCGACAACCAACTATTGCGGCAAGTTTCACGGACCTGCAACTTACGTACGTGACTACTTTGCGTCGCAAAACGCACTTGGGTTTTACGAACTTCTGCCTAAGAGCGGACCGAAAGCCCTGATGGTATTTTGAGCGGGGGCCGGATGATCCTTCGTAGTCTTCA
+
778I)%4=I(>I(448796324I(I,I/'6E&87I(95385I(9=9I/'I(7%I2(I(5>4775H'78II2*&I(8I(I)0H'<796=:933I(;48>@:I(I(8<34;;8D<7@I.&85I(887;549;847I(:95I7*9;66777I.'G'69BI(I(73I)2;H':I.&64577=983I0'I(I0'I/'I(7F'I.'I(I-&38I'I;+&95<I(I(H'<78I)6<I(9G'=I0'588I':I):74I(7I(22627:985&8799I3(96766;6I>,'59:<;I'I-&I;+&:6;I'7I(484I(9I(9858H'5I'7I1(6I/'4997I(87I>,'777<IG0)%I'I'28795I)I';57778<I(87
@simulated.139
CAGTTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATTAGCAAGGTTGATGGGTTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTGGTGAAAAACACGTGGAGCTCGCG
+
>7)I9*&I)6;835957H'797I0'<7I)499I(77755I)B6I'4285I(;87377773I(6<;6=G'694I(=3I)I(;I1(7H'28<6:8II>1*'8963835;1;F'97:;I2(>;5G'9I(9;77H'65;5I;+&6I(I0'8:4H'378I'F''9<I(I'I,;83I/'I)I(537857699>2;I0'7=6G'7I(I'9I(5/3:I(:I*6470:659:79I(;4:87I(I(;56I-&I,76<669I'94;4E&H'I'9;:9H'I)1983669I,&:6I-&4I.'I*G'5H'9I(:5489469I/';:44749I;+&;I'6I(888I0':67:876<97I'58I'8>6;839I'4;;I1(;8865I(4I):I/':I'76II3+':;649D&9:7:=978
@simulated.140
GACGAGAGTATTGGTACATCAGACTGCAAAGGACTGGCCAAGTCAATGGGTTATCTGGCTCATGCAATACGCAGTAACTTGCCAACCTCGTCTGAATGGGAAAAAGCTAGGATCACCAGGCGGTTGCGTTTGCGCACGGCAACTACGCGTTCATACTATCAGTTAGATCGATTTCAGTGTGAACGCAATGACTCATACGCTCCAATATTATGACCGCTACTATAACACGGTCGGCTAGTTAAGTTCGAACGTTTTCATGGCTCCGTGTTTCAGCGGCCCTTGTCGACTACGGAGCGCTCAAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGTCTAGTTGCGGAAACCGGATAGCGTTTGTCT
+
:'576<;7=7I(G'4<:93695566;4I1'I(678G'G'I(:0:I'8I.&I)8>;6H'87863<5I(48=:;6=7I(6I(8E&F&H'934566:I'6I0'II2*&77:;I(9589I(8I(8I)I(44'I.&7=:=66I)?I'8;80749H':784942=648I(8/895:;I3(79982;6I(3:7I)799@5498:685:I)I(5>I(=>65I(:3;<5896I(783I(:=I)5=%:H'I'(I'<>I(49I7*&873I)94I(;69I/':756I'I.&I)988:5:178I(99;8979H'96I(I/'I'9I/'=79I(=759954I(G'G'83I(ID/(&5847I(14I(I.&I)I);97572I0'6423
@simulated.141
GCTAGTTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGTACGATTGGTGGAAGACTCGTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTACCGCGTGATTGTCCATGAAACACTCGGGCACCACACTTGATCGACA
+
:;C3&I'96I(I0'I(;;8I(56I/':73<9<436I0'I':H'4I(88297;37:I3(6I*;8796I(I(>97I'I1(7I0':7254<33I/'9I(5:4G'/F'5I'444<3I(/4743::7:=;9;I):8I'479:78698I'6;8F&C6H':I)9I'33I.':8697::9G'I)7:5E&9I?-'7977?&39:7I(F&9I,I)49675%59I(6I)447I2(I0'7:I.&765I'996969895F'87914=5I/'I)78II3+';664I0'59G':5696I+9@;7I(I(I.&H';I8*&<85I.&:7I)I*I(7585;<;H'59:I*D&I(:696:7G'=54I(;6;6<I(I)35I(67H'I'&I(57687;I*93F'695I3(9585:I3(96I(655'G'686:8229
@simulated.142
ACTCTCGCATATCCGCCGGACACTAAGATCTGGCACCCCTAAAGCTGGGCTTTTTCTGAATTCATCAGGCCGTGAGGCTGGTATGGGGTGCAACTTCGCTTCCAAGGAGTCCGGCTTTTCTCCGCGCGGTCGCTACCATATAGGAGAGCACATACACCGGTGGGTAATACGCGTTACACCGTGGGCGTCTTAACCCTACCGGCAAGCCTACCATCAAGTAATGGAATGATATCCTGCGGGCCCTTCTTTAGTTTCTCGCTAATACGATATTATCCATTCAGTATGTATTCAATCTAGGTTAGCAGATGCCTAGCAGGGTCTTGACGGTAATAATGCGTGGTTCAAAGGACTTACGGGGAACGTGCACGACTCACCACAAAAATTTACCGTCACAGGTGCGAACTCATA
+
997:::366761I(9I)G'699:6G'56774I'3=I@-'8I.&997I4)6II0)&374I)I(16<39I)I'=386I(37I(264I:+&653I)CI'878G'H'F&F'836I)I'3I<,&B:I'565:I(67524:I)5575:I(797674:559?;I'I(5I/'9F'653573I(<>7I'71I/'4986H'I(I-&:;I(I(4G'3I'83I)578I(86I(6H'G'3:6694I(7:2I0'I-&I'7I0'56I-&846777I(2023>79I)79I,@H'7;58:2<46I(9I(984>I'I(8996<<46I)83654I1'6:I(9=9I)8I(8I(:9539I)F&9I1(H'85I'67I;+&I(39@7:956:96<8H'69II0)&I.'9I(9:7:4;I(69=8I+356267
@simulated.143
CAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAAATTCGGAGTGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACAGTAAACCCCGCCACACAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGTACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTTATCAGCGTACACAGGGATTCCCAACTTGACTGTGAATAACAGACAGGTCCAATTGG
+
97604471I1(:6I4)I*>I2(96I'=289878I(<I)7978I.'?4I*I(:93I'8577799863:9:697:6;;4I/'I)7:94I(<=:I(I-&I(;I*:6628>5748I(1I)3I'37;=<71I(6F'3898878II8-(%3;5<8714I)H'7I*57697:476696I/'9<98F&<758I(88I.&57H'I0'77354:<=9G'I'6:79677A66778I,9G'56I(;736I(7766;69F'4I*27I(6569677I/'I=,'8I(6<;5159:8I(18I0'I;+&85:772I1'I(8H'I(I(<95:%857:I0'I)8448I3(:95F'I(F'I(469;I)69998H'4I1(5:>4:::77D:;9I/'8I'I0'I(8E&>381887I'4I*474:48I)6I'I(I)I(
@simulated.144
TAACCGTGTGGGCTGTGTTACATGGAAGTCCTAGCCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGTACACGGAACATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTA
+
6I(I(8478I-&9A972I'78:5I,H'(;H'873I(66I+I.'I(7263I=,';7777585665I(9649:6;;6>689I(,753<I)I(63I'5<8I'I)I'939503G'E&489997488<I(738C87I>,'598I(4I(9;I)I.&I(7;8I(8:I.&866854;56I-&I'5I(8I(7949=3959I1'9I(75::6I'I)998I(I.'4I/'8724<99<I0'6H'5;5E&8I(8H'67692I(6><43;6:78646I(52I(26469769<E&94;H'85I(9D&4I(:;I/'7:8:2638I'I(672D3I8*&9435:8797I)I)@I1'F'93=587;I)9I'44;I,&I/'85I.&6=5I(74<72:7?<I)1:26732I-&I(67II1*&5889I.&<84
@simulated.145
ACCGTGCTCGGAATTCTGAATGTTCCGTGTCCGACTCGTATGTCTAATAGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCTATGTAACACAGCCCACACGGTTATGGACGCTGAGCCTACATAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTGAAGTATGCAGATAATTGGCCCGGTCGCGACCATAAGAAGCGGGACGCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCGAACTCCGCGCACCTATTGCTGAGGAGAGGTGCGTAAC
+
4I(77<:55I'G'I)829I(58I(I(5346I(9649366:886;8I(4&8776835;:6I8*&>996H'I/'I'3@E&5:5I(<I(I/'(;82;I(::138I2(61?5I(I(78I(659478=<I'5B39D;;27<2I.&I(95I':9:<>E&<I(I(672:47I(376<;I(48I(7;97.9<787H'H'I'I.&I)5:::7'I(::F'4I(66I/'948I':I(51=99669886E&;<1I2(I(7368I(74;I)I(57I1(4-8H'7.12847I(756H'785883;88=;34575666G'97I(845H'43485>6580I)644:I)'I);;I'49897I(57I(8::4>I(;5<I(5:906I(6
@simulated.146
TAGGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTGAATGAAGGAGGTGATCTTTTTGGCTTAAATCGTTTGCTTTAACGCCTTAGAACACGGATTTTGCGAAGATAGGCGCAGGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGATAAGTCGGAGCGAAAGATAGGATACGAAGGCGCTTTATCGCGTTGAGAACCCATGTGAAGTTACACTATTGATGCGGCGACCTGTGCCGAAACTTCGTCGTCACCTGATTGCCAACACAAAGTACCCTTGACGATCGCTAGGAGTAGGGCGGCTCCAAGTGATCACCGACTAGCGGCAAACGCGACAGTTGACCAGTGCGAAGGCATTACCCACTCAGACG
+
:'I)72G'I(7;I)6965=I8*&8I(:;5I.'8I(55674;69<6>I(89I/'34364I(59I)07I(/9I(I(;I*83;88II2*&I(9I(I.&519I0'6;I3(I(=0I(G'97I(998I(5I<,&79;F'4998H'8835II2*&77697926G':759I*79:=I(5I)I3(II2*&86I(9*9H';:-<I2(6=<5I(91?75G'H'=45I-&86728:I)667H'I0'3;799I(7F':88@94I,8855=I*9)8I':498I):I2(:E&975:9779H'8:8F&9I'F&85:I4)99?I1(I(;43>8876767E&/465I/':I'58I(I(35878<;I(.975887F';I0':35:5497I)58I(747964I)I(:7I(=I0'98;<699:6
@simulated.147
GGCTCTATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGGTAGCCGGCACCGGCCCGGCTAACAGCGGGAGTGACCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAA
+
I'258%:4=682F&6I):I(I)97:H'I(87:2:I(II>1*'785F'I)37I(I(I-&G'56G'4858I/'9779&I)409;26I(8;I(6I(:869I)8F'I(I)I(I9+&6864I)97I-&364<;87F&52:I'<41871I4)59871I'I1(<;7I':I)7I)9I4)54435775II4+'7I)H'?<65I.'I.'29595=8929I(I(I2(28<;79::/I/'I(:8;I)8=I)88I.'I(8;:8666F&?76E&448=58I(<56889:25I(58I)3I)I)I(53I;+&<756872H':7I(I?-'56;I(87I0':881I/'?I(I)688I/'17685;I(7667BI)9I)I(67478379I3(578::I0'<:0::6:I'
@simulated.148
GCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAGTATAGGTAGCTACACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTACTTTATATCGATGCGCATTACTAGTTTCAAAAGTTAGGGGACATAGCACCAAGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTAAATCTAAGACCCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCACGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTA
+
=I):746771F&=F&<665G'29I3(4=:6I(6<;3I(35:<I';I7*99796I'3777%9:78=54;8<I(43673I/'5889I(96I'27I(9588:I'7I(I(88766I(99:G':77F'765577IB.(17I7*939:51:385:3:I('4378I,&7I:+&3H'6I?-'69:95894H'I,D94I(7694:9I9*&4I'I(55I'899:67:BI-&79;F'2<I<,&I.&5I0'65I<+&:H';64674574985I'9G'59=77761:4I)4:9I';98988=;75::1I(;845H'489688&I(64595:458>I*3:I1(8I(:4II0)&867576;6;7H'::9999;I(56F'5:662;9I'I/'695489=6
@simulated.149
CCCTTCTCAGACCTTCTCTGTTCATAAAACTTACGCAGTGATGCACCCCGGATAGCCCTTCAGGGTAGGTGTCTAGATATGCGAGCGACCGACGACTTATAGTCAGCTACGGTCCCTCAATGGCCCTGATGCCTTAATCCCTAGCGGCGGGTGTAGCGGGTCGACGTAGGCACCAGGTCAGCAACCTGACTAGAAGCGGGGTCAAGCGTGTTTAGGCTGGGCATTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAACCATGCTAGTGCATGAAGCCGACGTATACAGACTAGTCTAGGGGCCTACGCGCATTAGCCGAATGCCCCGATGCCTCGCCTGACAGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAAC
+
I.'G'898752H'I(9:997I(4>7I:+&9I)67:64&99493<2I=,'F'87<;I0'G'48I.&89I(:44789877;4459616<7I(5;624;I'>9783>786335I(5I2(8:H'7I'I2(8>=23I(I,I'6I.&797?H'5I/'664474I/'53;8:%9=I):8I(6E&89765I)I'48<:;66I'99I;+&<5I*781:9I0'7I*89I/'<;I(:05:<;7657761G'I/';8:7863I)96I(64947426I5)I*623377;7;55:5I'5I(577968897;679<99&:97I=,'I(99:6-878I(59I(6I'59I9*&<;-5I)783F'4689899E&:4I(7I'I(27I(>45?I/'75I(G'9I<+&I(6H'>;8776G'67I'@:6G'848H'8:68I'I/'8
@simulated.150
AAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGCTAAACTTGGTTTATAGCGGTTCTCCGAAAAGAGCAAACTATTCCGAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCAGTTCTTTTTAATAGCGGGGTGCCAACCTTCCCTGAAACGTGGATTAATCGGGCCTCTGGTACCGTCAGTTCTCAATAGCGACAGAACACTGATCTGGGGGCCCAGCGATGTGGGCGCTTGCGCGTATACGATAATTGGAAGACATACGTCAAGGG
+
I/'58I0'8I)9I(6303795I.&6II4+'I'49I@-'5786<I)844;58769:84;666;I(:;<5I0'I/'H'178<744I(8966:5I)H'89I/'894478@G'>6467I2(9F&H'I7*78437I'I(79I(6I<,'9864I/'776G'I(58I':88;I'I(9IB.(2I'I)<I(87866438:29I(65I.&63H'1I(6G'I*23686I'788I9*&I)4I(679G'I:+&:;7I1(7;H'9IG0)%I(7726I<+&7:I(I'F&E&I3(54I1(7?6H';I*I)84I/'I(77:I(9:H'A4656I(9>7I(:7?7A>797I)68;748934IH0)%I2(>6346947I2(468H'3=3<&3;44699:I'I(I(I(=;5845:8<9I(I1(
@simulated.151
GTTCTGTTCGTCTTGCCATGATACGACGCTTCCATATTGCAGACATTGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGTGAATGAAGGAGGTGATCTTTTTGGCTTAAATCGTTTGCTTTAACGCCTTAGAACACGGATTTTGCGAAGATAGGCGCAGGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGATAAGCGGAGCGAAAGATAGGATACGAAGGCGCTTTATCGCGTTGAGAACCCATGTGAAGTTACACTATTTGATGCGGCACCTGTGCCGAAACTTCGTCGTCACCTGATTGCCAACACAAGTACCCTTGACGAT
+
:H'577I(:7:5I)6H'7606;96;3373I(I(5;<I(77;9633I(C32G'I)58I(67;5=I<,'4I'988I/'6I(37984758863H'99I0'87885H'=8D;@I)96I(I(<H':7876II4+'H'6I(I/'8:<I0'98I-&I(84I(H'74H'73:H'?I<,'9;8H'4;;9G';65:IH0)&57=57328I'449<I(;675I(:I)I.&II4+'85I'9;F'6?7:I2(6695H'55756I(I):8;I-&764687I)688H'I4)0;888I)2I(372798I2(85597I(57I(87=<I(1I0'9I(7::;:993I(458I'0F&G'71;I+=6:I3(I(4<4866
@simulated.152
GTAAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTTATGACAGGACAGCGTCGAACGCCAGCGACTGGCTTATCGTCTGGGTATGCCGTCACCATAGCCGAAAGTATAGGTAGCACACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAGTTAGGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCCAAGAAACACCCCGAATCACTATGCTGTCCGAAGACGA
+
5%I0'7397;::77I/'I(7I(89956I(656I0'6I*E&H'669<;I(7767/<;785;56I'4D&994F'I(I'3G'8I/'=I3(:899;BI(7<5935:&4I)&5I(<635867I(3F&1777B77I-&63=9I'8:7>I(8786H'7I6)6/936I(6;9775:7B99>;3I(=>9=2I.&8:56I(67I(95I'67898H';G'I':88::I*55<F&943I)>595:8II3+'26I;+&446:8767507<8I';17<I/'4I=,'5I*3I@-'6666368:I)I.&I(75I'74:545I?-'9I)I(99I(9786;;5I'I.&687I(:6I@-'I,9I-&64I9*&9I)54;877;3<3:2I(9I(7'987
@simulated.153
CTTCATTTTTTGTAGCCCCATCACCAGCGCAGTACTATCGTTGTAAAGATCTTGCACGTAGACTACTGGCCTAGCCCTAATCTACGCAACACAGACGGTACGAAGCCTTTTCTTTAAGAGTTAACGTCAAAAGTCTTCTACCCACGGGTCGGTCGCGTGAGGCTTGTCTATCTGAGTTGTCTGTGCTCACGGGGGCTAACCCTTCTGTGGCCCGGTTAGTCAATTTAAGTGAATATTAGTTGTATGACTTACCCTAATGAATACAACGAGCGAGCCGACAGCCAGTGAATCGCGTCGATACATTGCCTTAGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGGACAGCATAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGGAGC
+
4I(8?II<0*&=766I=,':553I)4949=;790678489I(88I0'6549I(96688;0;8:9594I(I)7:1I/'7G'7466898I':754;38F'896;I(=I(I9*&7I2(H'95'I(I(:<5=I@-'785I,676I/'53I2(8'I+:;679478I(<I):93;529:988I*95A77378>47;II3+';9I(I2(I'4893I(I0'I(I(8:=7I)I0'I,446I'5;H'50H'866::66I(6I-&DG'86I(677I)4964:)=5I(59973I)45:2I(651?88'787428I(4F'F''I(I'<:I(I(=<997H':I(I(5I.&<379:237:474:876<I)76H'9I-&856;6:584379I'6H'4II1)&995I(85854=49I/'I(6948:38I)73F'6::>6<7I(655
@simulated.154
AAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTCGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATTGCAAGGTTTGATGGGTTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTG
+
I(61839;=I0'4I1(;<7679:I)796G'96I(74I-&<II=0*'7I8*&I(:747<:26H'59:I1':2I(5:6I):3945G'88I*7:69I)@7758<796I(66495I(7<6I((73I'I'9I,&3I(>:7577II7-(%869<418;86I(6?1:I.&678I(;I(0258I(7875I:+&:E&I0'56=I(6<7E&I(=6F&I(I2(78<I,&I(I'9:8<;963@8;8I3(=8;I)4I+I)8G'885;H';I(;:6869689;4H'98774I(I)>35I,&I0'8:?847I(:72;I'H'I)=788I(I)6712698I.&09I/'6I3(H'I(5I'0I'848<78:6I0'567?>;3I@-'9I(7I(43;I2(8587946784I(93I(7456;7:I(;<7I3(6?462G'6I(9I-&9=
@simulated.155
ATACTGTGGCAAGGGTACAAGGTCTCGGGGTGGAATACAACGCTATAGCCGTCTCAAGGGGAGTGAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCGATACTACCTTACAAGCCGGGCCAACGCACTATGGTCAGCTTATGTACCACCTCCGTTACACTTAGTGTTGTTTGCCCCGGCTGTTTTATGGCCGGACACGGACCCACGCGACTTTGTGCTAGTACAATACGTGCATGGTTTGATATCATAGGATGACATGTGGGCACTATCTTCCATAAGGAAAAACGCGGGCACGATTTGGTACGACGAGCAGACGACCAACTTCCTCTCACTTTGTACTGCCTGTGCGGGCCGGCAAATCCAAGTAGTTAGAGATGGCGGTCTGTAGAACTTGATT
+
;866744H'9I(I0')43I(I)84>:I;+&7H'G'585I(88/&5433I(9;98;H'I9+&43851>I.&7;I(5789I'889::8;:99567<:G'8:888876F&I(89H'8I(I4)I(G'739856;0I'66584I*29464G'7I(1I(;G';862I(/795I(3I1(3I<,'E&892I9+&;9I(I+I'3799G'5I.&7988977I.&84786:=6:8I(85868;978I(I/'>;983=57:I'65<67:353I-&96:74=5I*I(87I(I'II1*&579I2(775;5I/'I(97;:325:9:723558I(I(;I(I(:5971;I/'988988I'46648I2(I(I(3I3(5I(I)85;7I)47:7<:I)6I(&4575;9I,7I(77E&
@simulated.156
AAATACCATCAGGGCTTTCGGTCCGCTCTTAGGCAGAAGTTCGTAAAACCCAAGTGCGTTTTGCGTACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGCTGCTACTGCCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAAACTAGGAGACATCGTGACGGAGTCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAG
+
I.&3<I)5645I-&;I/'8H'2I(9888I'<I)8:7I*6I(677I:+&I2(E&:<:86I>,'<=9&3@;7I-&659:636668779I(6H'7;=I'6I(679I1(;I*6I(68H'198I'H'I(8;:I:+&I(3=I.'I(I.&H'6I(I.&I1'G'I/'5888:5=53I-&9I(67I)86I'I(3:5I(I.&7579;<:I:+&552I)<:48453:3:*7I(5)6I1(57=G':34:265I(I(13668<I'8:869478>H'9I(E&6I(II1*&<8I'8448:6I(I/'6I(I0'863G'5:6/6I(85I(:I-&I0'I(7=768;997I(;I'88I(6<8;45:88156I9+&86I(I)I'I'I)/<7619795I(2
@simulated.157
ACGGTATCATGGAATAATACTATTGCGAGCTCTTGAAACACTTACAAAGGGCATGTCCATGCCCAGTTAACCCACCAGTACCAGGTATCCTGCTGCGAATGGTCACTAGATCAGCCGTAAGGTGCACTACCAGAGTGTTCATTCTCTAGTCTGCTGACTACCAGTATTGCGACGTTTCTGGCATGTTCGAGGCAGAATCTTCCCCAGCTTAGATTAGGTTACCGCCGCTTTCAAACTCATTTGTATGCCGGCAAGCAGCCGTATCAACGTAATCGCATAAAAAGGCAGGCATCTAAGTTATATTGCATGGCATTGTGTGTCGCTTCCTACCTTCGGTCACTGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGACTAACGCAT
+
56H':7886;I'I'8I'7:59@I)6;88A47>I(9I1'75'G'6:I/'I.'66867H'896I2(48I)I'I/'4I(::57I);I(:31I':;::69<I)0I'7::=4:7758/6I(5<I(H'7;7867'I)566448I(96I(8:47539284;<93486I)6458I(7:9598I0'9;I(<588I(A88I)584I(99I(I:+&746I(987I(7H'I(9I(4H'89I0'6I/';399I0'=76;0I(I+2I(7585I'97871G'745I(<49==4II2*&G'39I(;815:I(%I(56:I(5?78I(:4I(72648767:I'H'76F'I(6I'9379786474H'7;85I(>;489:95462E&24:79<I(67G'D;89I)67476
@simulated.158
TTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGGCTGACTGGGTCCATCGCATGGAGTAATGTTGAGGGTCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGTCCTGTCTCCATGTTGTCCAACGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGAAATCACCGCTAATTGCAAGGTTTGATGGGTTGGTCATCTCGACATCCCACTCTTACCAAGTTGTAGTTATTCAGCGCTGAGTC
+
H';6I(I(43I(I)4765?:4I(263I)I(9:2;>71<:<4>I'7I)6:58I)6:;I(8I0'G'I';874I*2I(:5998H'6396?I(7779I*F':3=566I3(9I,6978734G'4:>I)68I';4I0'7II5,'7I9+&H':78798;6H'795I0'87I'7=6I(:956=I*85I(76<<I'38:7;:4::'I'194:4I(576I(93I'I)&9I.&7I(:86910II7-(%<627;<797;I'>=45I0'89:I(9I)7=:<I(77;>I=,'7CI0'886I)81:I'I(:;I)I)I3(678I/'I(I'7:84827>9376I/'8%85I)7F'H'8H'7431I(5I,65;:76967;47
@simulated.159
GTCTGTTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTCTGCTCGTCGTACCAAATCGTGCCCGCGTTTTTCCTTATGGAAGATAGTGCCCACAGTGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGGCAAACAACACTAAGTGTAACGGAGG
+
:9885I/'87I'G'2I:+&H'6H':4:76:I(::I(832I'87<I(8:;:I'I.'9I(7I2(I.&2I.'7H'5I+478I(I;+&68=:=96:95I(5H'I(7:I)I/'578:838I0':8I)4<I(<I+9I)76I(I)?464303:58395I(67663:789I<,'8I'<I(45E&4I1(615;:8I(8H':97688H';4:9I(I(7I/'5H'F&I/'9795:E&692956I1(85:0:5I(I)9I)I)8695;8:;:55497;AI(I.&98728I/'656II5,'I)I(88I)I)9759819I/'867(;=88<9I'775:44=49I0'I(89784780:I(6727676769I1(72=6567I1(:I'8785I(I'I(3<I8*&7;:H'I;+&;I/'9I)7879G'36:6I'8G'7I(
@simulated.160
GTCTGTGCTCACGGGGGCTAACCCTTCTGTGGCCCGGTTAGTCAATTTAAAGTGAATATTAGTTGTATGACTTACCCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACATTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGACAGCATAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGGAGCGACTAGATTTTTGTGGCAAATCTTATCTGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGGTGTTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGA
+
:76::=986779II2*&88I(I-&I(9997I'I/'I)I'::65I(I0'I/'473I(?7F'57I'599964;I(:I0'8H':9I'599H'3241;77G'64;78I)7:5;I)852478447:;4G':I(I'I(I(16I)I(73:74I':H'F'5I.&9977@:9578;885879I(78H'7I(2572989:5;;6I(4I(4IH0)%49:G'896;787=I-&G'9667288G'68I(;897::9I(7563:58757II1)&86I'5I-&48I'86:9652488I(678198I(=:<>H'9326<;:767:36I'482H'8;9988498;I(2I(589434446884H'5IA-'65I/'7I0'I>,'96I(:98I-&I(788;:68I'64H'I(6I;+&3663447
@simulated.161
CTAACCCTTCTGTGGACCCGGTTAGTCAATTTAAAGTGAATATTAGTTCGTATGACTTACCCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACATTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGACAGCATAGCATAATCCACCCCTCTCCTAGTAGTATTAATGCTCATGGATCGGACAGTGTAGGAGCGACTAGATTTTTGTGGCAAATCTTATCTGAGTACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGGTGTTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGAAGTCCTTGGTGCTATGTCCCCTAACT
+
68I(I-&I(:898I)&I-&I(E&763;E&I0'I0':56H'76I'29G'(;44:6:6I*4I.'4I(?2I(947I)58987<7I'8::?8I(2335I'7;97=<:99426I)8I(I)I'G'96I)I(88.17I(;F'I'6I/'7697585839;578468I(2<H'7G'8685569:9:99E&7I(4IF/)<77I(44:79?:8I+I(;9786;;I'83%F'%66>,<64I(6:8385:>77II3+&88I(7I0'74I'157::6:&554I'?;;8>5I(::9=I'98<978972499;I)9;8G'46:;8?7968I':I(:5=88889986:I)5I9+&76I.&<I0'I=,'9:I)378I-&G'6897:97I(98I(H'9I?-'878692I(85I(I+H'4683837@I>,'5I)6=
@simulated.162
ACAGTAGGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCCAGAACGATAGCCAGTCGCTGGCTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGGATCTTATGTCTTCAATTTGATCTGTGCTTTCCGACGGGACAACCCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCCGCTATTAAAAAGAACTGGGTGAGTTTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATT
+
2D9464I2(:<;86I)6975:67:550347I(24;99I@-'6H'74=5I)8:2:I'6<7>I-&79I(2751C6I(13765;.I)<I(:;<6:654I(56:9>7I2(1I/'0I)8I(I(I)9;1I'8I(36975955:7395I(97684H'I(I'2I/'7:7I(58748G'7I'I0'7<9674:75I1'I('<3I-&<>G'I;+&G'6447;59758I(I)H'I)371;754<6552F&549I0'3596=478I1(II1)&6:7946766I)786548=85G'857I)>9>46I(57I(;68I(I,&7<H'I(9I)667I.'7<I2(I(I(I)I(66I9+&8969I*IG0)%7H'7;I1'::3&I;+&I(7;7H';I*I9*&97:E&68856I(I(6I(:I(65I)
@simulated.163
GGACTTTAAAACAGCTGCCAAGTTCCGGTGAGACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTTATCAGCGTACACAGGGATTCCCAACTTGACTGTGAATAACAGACAGGTCCAATTGGCGGGTTACTGGCGCGAACATCCCAAGGCTCGTTAGCTGAGGTCGGGCTCCACCAGAGAGAGTCGAGTTAAACGGGCCAACCTACTCGTCGTCGAGTGGTTTACAAGCATAACTTGGCACCCGCGGGGACTAGCGCTCCTTAAATGTCCAGCACCGGGATGTGTGCGCATTGAAGGACGTTAGGTGGCCTCTATTACGCCATCGAGAATGCGTTCGCTTTAGTGACGTGATATAGTGCGGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAG
+
I(98I/'I=,'13==3:I+H';I(I'G':345:;?9I0'I)3566I1(748F'I(I(I(:<76I(73;78I(;I-&849978:6:D894I/'5I(I0'I(8I'9:88=97I)>G'95;696I'5I(I)I(I):I.'I(875I(;783I(99:I0'I(I(68<:H'=49:=3I(87I0'27I'8I)2578?76784<96H'I-&6I/'I'I(G'<7:3585866<4699I)I2(95I'1>;:I(5G'I'6:I-&95I;+&554=:82;5I(I+I.'877I(4667I(I1(:67469:9655I(:I(I'475I(<I'AH'H'48<=H'846I(45:96:I)6;9;I(86:I-&:757874689558<5696II1*&I*876;9981I)9;:?I'G'F'86I4)4:58I*=8I(;6:;5G'7
@simulated.164
CTAAGTCATTACTTACCCGCGCGACGCAGTCAATTACTCATGCATTTGGATAAAGCAATATAGGCATGAAAGTCTCGCATACATTACCGGCACGATCATTTTTTCTCGTGACCATTCAGCTGATTGAAGTTCTCGCACACTCCGAATTTCCATGTTAGTCACCGGGAGAGACGTACGATCTAGCACTGGCGCAACCATAAACTCGTTCAATCTAGCTGGAGTTTCAATTTAGAAATACATCTGCGGGTAGGCAACCCAAAGGTGTTTGTGGTTAATCATCCGATTACGAGCGTTAGCTTCCGCAGCTTTTAAACCTGAGGTCCGCAAAAGGACGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCTCAGGCCGGAATCACAAAC
+
85I'2974I(27I';I0'7A73872;757=;F'I(8526@7<44I/'F&5:I/'43I(75<4I'9577I1(59698777548:G'<I(I(38988646II7-(%8<58537I(3I*65;<785I(;G'6H'9<4959974<I'4I*I/'I(::7H'&1326G'I.&569.163:1655:5859:;99I':3=I'I'95I/'8959I(3I(57863<=I'95I2(8I+I2(9<I0'5<26837>9I/'67I)8I*I-&I0'I(91I/'78I'I'I)686:I(75H':9<578;I(7/;I'I(199=8I;+&I/'I(47:E&9I(=4I:+&I)%9I(8:6I(858=<6?H'<:I);969I'68<9?8I9+&9I*79I'5<F'9I.&4447686I'I'I)I(64:8I2(6
@simulated.165
CTCTTCTAGGTGCAAGCGCTCCGGCTTATCGTCCATCGACCAGTAGGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCCAGAACGATAAGCCAGTCGCTGGCTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGGATCTTATGTCTTCAATTTGATCTGTGTCTTTCACGGGACAACCCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGTCCCGA
+
47=I(877H'93:I*66;66I(I(2I(64:<<I(56D3:I(8269I0'9<456I(;=>8433676:656F'594:;I;+&4I(571:H'2584I'7598I0'96I)8559F'4I(;;95518I(5H'8=6;275>H':5459:I-&5I-&4G'3I'I)I)=93I)2I'68;:779775?88I*6;958I(I(I)8I2(041I)6798:I(8H'I0'37:<;::5(8I/'D>6I-&87I)I;+&I(86:5478554I(I(F'I(;8957994;578I)595I/'1=795693I-&IF/)59688<947I)7:;<83:56I'47;I)758:8I(9=I(857H''I.'79
@simulated.166
GACCGTGTTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTGCGTTCACACTGAAATCGATCTAACTGATAGTATGAACGCGTAGTTGCCGTGCGCAAAGCAACCGCCTGTGATCCTAGCTTTTTCCCATTCAGACGAGGTTGGCAAGTTACTGCGTATTGCATGAGCCAGATAACCCATTGACTTGGCCAGTCCTTTGCAGTCTGATGTACCAATACTCTCGCATATCCGCCGGACTACTAAGATCTGGCACCCCTAAAGCTGGGCTTTTCTGAATTCATCAGGCCGTGAGGCTGGTATAGGGGTGCAACTTCGCTTCCAAGGAGTCCGGCTTTTCCTCCGCGCGGTCGCTACCATATAGGAGAGCACATACACCGGTGGGTAATACGCGTTACACCGTGGGCGTCTTAACCCTACCGGCAAG
+
9;G':67I(79;7779;I'899;I';3I(H'97=;7;5779779I(787E&8:69778I2(664:>89I(759:592<:94I(:89791;I':I(:6:377I/'95H'H'7I(<D9;99H'7859II1*&I.&7I(8<4@5::I)I'I(1I'5I)869:<9.9I(;:98;<7I(:26;H'I/'<H';77I(I*H'663H'I0'85677:79;:895I(I(475644:8566>7I)9I(I(;<&><5I)8:58=I(59I9*&8I1(@;<I.'7IF/(>65I'H'82;82I'I(1:97G'9;I)86:*I9*&189I(:G'7?0I'I(G'I'8@7H'H'9I>,'I(2I*8737H':0547>I(9<>77I(66974497>>63I(H'6I-&3I(7;<=;5I(8<3I(75I.'9586I(I)I/'5:G'H'8I(5
@simulated.167
TATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGGCAAACAACACTAAGTGTAACGGAGGTGGTACATAAGCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGGCTCACTCCCTTGAGACGGCTATGCGTTGTATTCCACCCCGAGACCTTGTCCCTTGCCACAGTATGATCGAGAATGACTAACGTGGCCCTTGCTGGGGCAGTAGGTGGAATTGAATCGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAG
+
74I(779:=;978=I/':98;8:7I0'<I(7<76G'I(I)6:I:+&33:E&I;+&7I0'<I'6<88G'2335G'3I(7I'9I(78953H';3849G'55469554I(I'I.'I(6H'69I(I(69<<78>:I(7;88:79879:168<I(:4=;G'97I/'95:855I6)I)<28;;I)5883357I(<57I)I)7I;+&;488I'I)54I0'I(4I):2641846745765I(85:6;H'8';I+I4)G'26:I;+&76)96H'7I(I'I)5I(7';9G'4886I'I)955988=5969G'I)787I'I-&<I)A9;I)48359E&59G'I):77I(645I(79?:?I)3I(8F';64F&96:I)686B/8;2I(0>88IA-'57I(57:8789:I'0I(5I/'I1(4
@simulated.168
ACTCATTTGTATGCCGGCAAGCAGCCGTATCAACGTAATCGCATAAAAAGGCAGGCATCTAATTATATTGCATGGCATTGTGTGTCGCTTCCTACCTTCGGTCACTGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTAGCCACTTGAAATGTTCCCGAGGGTGATCCGATATGCTCCCTTAAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGTATTGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAAGCCCCCTATAGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCTAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTC
+
67883I0'48374E&I(6I*5934I)6:983H'@;6I(67644:II2*&I';:I(9;76:I)I(385H'5696I(3:I(3242751<5I)I(83I(I(5I)7877644276E&77:8I(:3999743:88I(?5363<I'/2F&I'779I(7/964674;9479F&97H'%5H'<9I(4I0'6;I(I1(5:I.&1<51F&+5:849>6I0'F'I8*&;7I0';86I>,'4H'I(I)I(8=4249963I(<54:I(5I'6I*5I'7I,<4I)D68::25I':6<96:43I-&9I)E&7I/'9358564I8*&;I0'9II7-(A<:':68597877H'H':?I)676I/'=69:687657620;>I(65==67I.'7I(67574&68I(9I'9;8I'7>53II0)&6I=,'3:7G'897I0'7
@simulated.169
CTACCCTGAAGGGCTATCCGGGGTGCTATCATGCGTAAGTTTTATGAACAGAGAAGGTCTGAGAAGGGCCAGGCGGACACCTGCCTTGAAGTGACGACATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCCTACGCCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCC
+
987I/'77I(I/'4987I(I8*&63:&99:728:76G'9I;+&8:6I(736:6I(I);:5775F'I.'I(5I(5I(886I(:8I)I(7H'77;2;:7558F&;8=5234659568=7I)1<<7:65;458I0'223845:;832:757=2I8*&557:;5<I1(/5:6G'I.'I/'8F'I)796;I(I(56336H'7;D&63:7H'9/=59919978I(75I(:I0'7<I)577I(;58I'=67:24675I'7875;855766F'16896939:4I.&4H'G'5855I.&<5=I(II=0*'583I(;66H':9I(78I(=82;6653H'4:6/6:9<I'6I1'86I.'07=754:H'6575635I1'899=>I1(56756794I(F'8I(7<7;8G'97?>85I.&876I(I(7I-&;97:I.&::I(:59I0'
@simulated.170
GGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCGTCAGCCCACTCACGAATACTGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCCTAGTAAGGA
+
H'9=I(/597I1(3984I(79876:I(99I(?I(7:95I):I(I(I)I'IA-'8864E&55I-&79<8:79I)><3I(6:3558I9*&::5;6I'I0'489H'9I(1F'9I/'57::8766II3*&9I'G'6456I-&I0'984=768377I*I(I.&96:662625I.&I(:77I'72I'<5I/'I'>:;6567H'966I(:8289:I(4918:9779G'96I(9I'I(I'44I;+&;:7:;:6I)35F'I<,&887G'46I,&7:88I0'9I(I(223I1'7:;4:9I)55;58H'7I(I(659:2628I3(8%8357I0'7:;93:7I(73587A<I3(76I/'7I'773;3864I)7779889:H'87I*62H'87<I(998II:.)&I)168I0'8594G'I(=
@simulated.171
ATCCAAGTAGTTAGAGATGGCGGCTGTAGAAACTTGATTCTTAGTTTTGTCTGTCGCAACATGTAGACAGACTTAACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGCATTCGGCTAATGCGCGTAGCCCTAGCTAGTCTGTATACGTCGGCTCATGCACTAGCATGGTTTTATAGACATCCAGCCACAGTGCAAACCGATGTACGCAGCTAATGCCCAGCCTAAACACGCTTGACCCCGCTTCTAGTCAGGTTGCTG
+
43I(F'6>;6I)><8<78G'5I(567668I1'1I(73I)4H'&7I>,'86697=555H'9;624;2<52685F'G'6:H'0I/'3I(76I(5=I0'77:9:;8I-&G':8H'H'6I(869:386762I;+&G'355I(8I(7I2(5I1(I.'5I(4I0'I)5/95I)888I'95<G'28H'773=3@I(7I)I:+&7I(I'6<I/'7745I(<6I*I'6I*8<F':6<78:3I':46I'<415I7*9:I(5I)6:F'967;7559CI4)83428283>8:88:57687I)6D:<?;6:9935478H'I8*&98<?8549I(57I(6866759I2(F'93;787:9<::;:H':7I0'25I(7I4)89@95I(78I<,&7>G'8737<;6I(I(7656
@simulated.172
GCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGAGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGAAGATTCTGCCTCGAACATGCCAGAAACGTCGCAATACTGGTAGTCAGCAGACTAGAGAATGAACACTCTGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACCTGGTACTGGTGGGTTAACTGGGCATGGACTATGCCCTTTGTAATGTTTCAAGAGCTACGCAATAGTATTATTCCATGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATGAACGCGAGCTCCACGTGTTTTTCACCACCCACCTGGCATCACCCGTCTTATCTGAGTTCAGGACAGTGTCACTTATAGGCGGACCCCTCAGCAGA
+
=I(II2*&744695G'665H'77291I)6685I(;G'I):9869I/'885:I.&7I-&64I(6I(>I(G'7I(475I(886I7*I)67I(2C7G':45I'9449I(97I0'7:8:57I)8<6;G'6:;579741:59<94::I(;8I(;99635I(5555:6H'I*79I*8176589596:7I)8H'94:5364I(8:3I(;I'50;:G'5I/'I)I'77I/':78H';4&767I1(I0':5F&37I/'5I(<67>8'468G'57:6:I(6I'H'677877G'>I'866I'I(5<8864=5:I)7><267I(;4I(9<587578I):=887II1)&68I*6I0':I':G';659>I.&989I)3185=86I'87I(;685957:9AI,388I'7I)7I<,&97678;64
@simulated.173
TGGCCAGCATGCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCATACCCATTTCCTATGATCTCTACGTTGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCCATCCGATAGGATCCAGAGCGTGTGGATTATGAGTTCGCACCTGTGACGGTAAATTTTTGTGGTGAGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAAGACCCTGCTAGGCATCTGCTAACCTAGATTGAATACATACTGAATGGGATAATATCGTATTAGCGAGAAACTAAAGAAGGGCCCGCAGGATATCATTCCATTACT
+
6I(I(88761@78I(7F&24I:+&95:99849:56;I)58;I(F'9I(<<:H'956I'5984I,858F'7I)692654515972:6:;79991I(F'9597I3(7I.&G'5;:>7:9795C9>I(83=8I(;G'<83I1(I0'4H'I(43I)7;I-&I(5I/'6:I)?89=I(4:I*5437745:8E&8I)557;8I*7643H'5:3546I(6I1'II3+'47H'8<:596589;<57I(I9+&6<I'97I*I-&7I*F';?:86I'7H':I(=;1I(43I3(;7934G'498:43;6I(F'2788I(4I(6776;9473I)3I.'25H'583568:I):56987I-&98I.&7I'I0'I,&<55I'266566H'I(:I(:39
@simulated.174
TTACATTCATCATAATCTCCCGCGAAGACGCATGAGCTTCGGCAAACTCGTAGTGACCGCGCGCCCTGCATTAACTACCGTTATCCAACTTACTGATACGAACCGGTTCCTAGGGGCTCGATAGCAGACCTGAACAATACGTGTACTTGGGCCCATTACTTACAGTAATCATTTAAGCCCTTGCTATGAATCTTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTTAGCGGGTATCCGCACGATGTCTCCTAGTTTTAGTCACGAAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTTAAGGGCTGGCCCCGACAACCAACTATTGCGGCAAGTTTCACGGACCTGCAACTTACGTACGTGCTACT
+
G'6>4I(67>768H'876I/'9;;H':86267>48;8I'5I)6I.&9945757948I)44;8>I/'9D77I(I'57:I'@I(85I(I)5I*688627696I)H'H'H'H';8I:+&<77998<;8784I(49E&8G'6=;6<5745I(I1(I.&8I(85I';9654G'863I1(I(/I/'I(566:84I(69II1)&I(=G'H'5I(7;:879986H'?485?<H'I(0245?8;I(765I/'&4AI)566384>2648I(0;8I=,'77:;77:I0'I+427H'G'7:H'93I(5I.'98;683264I0'I(I.'I/'I'8H'I.&I)I/'93I(I:+&957I(I(I'465F'::I(6I'6I/'411I':I(<7:H':I(584>;999;;6:78
@simulated.175
CCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCCGCTATTAAAAAGAACTGGGTGATTTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATTTCATTGACCATAGATGAGGCTTAACTTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTCGGAGAACCGCTATAAAACCAAGTTAGCTCGAATGACATGAAAGACCGGTATGTGAACAGTCTACCTTTCCCGACTA
+
I-&F'9:759789:6I(I(I(H';8>4<6:778;7I(:68I.';68C9:=6I2(II3*&8697>9367H'45849:49=I):43I(84995I(:9I(9>6I(I.&8;H'F'7I(765I.&39I0'I)G'I(I(85I:+&37<<I)II1*&9I'67I.&361I=,'I(838I)6I(I8*&86;I*59723I(I(8I'4I(98I/':7I)77D&<9787:49I(:I)I)9I?-'=I(E&733<I'7:I(I':3<I.&6<46I:+&:I(=2I,I(95596I>,'G'I(8I,<::5&7I)7<28<6:I0'<8I(I(<27:97I(46>4973I(I0'I-&70793
@simulated.176
AGGGCTTTCGGTCCGCTCTTAGGCAGAAGTTCGTAAAACCCAAGTGCGTTTTGCGACGCAAAGTAGCACGTACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTTGGTTGTCGGGCCAGCCCTTAAAGGATTGGCCCAAGGGCTGCTACTGCCCAGGACAAGCAAGGCGTGTTTCGTGACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATCATAGCAAGGGCTTAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGT
+
:I/'8I/'9I(4I(7<71I'2I(7:3I)9G'696I=,'I0'I(8785;IA-'98959;;I2(86826872:86<:I(9I(8::I(7I(77<I-&5I)9I'58I*14:I(I(I':37I7*H'67I/'I(I/'H'8I'I,I1(I)I4)749;977.3I0'7I';4I(74I+I(::<DI/'9896:5>I;+&>16I*5559573:662I(37I0'5;7I(338477<I(I(65>796F'75268658<I(3H'I)7I(II2*&69B:<5<58F&I1(3I(I+:89I(174:8I(77I'9I0'I.'I(088=8766:I(;I'6:I(823=:368:8:6I:+&0<I(G'I(H'I'56=5<3437I)86
@simulated.177
TGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCACTTGAAATGTTCCCGAGGGTGATCCATATGCTCCCTTAAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAGAAAGCCCCCCTATGATAGACATCCGGCGTTATGAAACTGTACAGTACATACGGAGAGCTGGGACCTACTCAGCCGCCATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTAGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATAGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTGTTATAAACTTAA
+
<551;I(75I+I(;84I)5:B87:7553;89I(5;I(6I(98F&8I.'65I)I1(06I0':38;I'84859=:I-&F&IE/(65I3(<89IA-'0I(I'I'I(69939;589H'931;I(7I(8I(5H'4I1(77F&I';6::49I(9<46966<I-&3I(H'8I5)3938747I5)6I-&9II;/)&29956989:778I(I(;9I(;96I0'4577::57128=7:>G'85=;?7I/'5G'1955977I(5I(:;;I(58:7II1)&7I@-'759I(943I/'G'587:997;8696I(6I;+&I.&>487487I(9759I(>8I.&134I1(3:<7<7>9896'<=8;7;;6I(898I(199H'71H':I/'349542I(89956:<19764<:I1(:9:G'6:73:57I.&8886:6I0'86682I,7I(26I7*7H'I'
@simulated.178
TCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAACACAGCCCACACGGTTATGGACGCTGAGCCTAACATTAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTGAAGTATGCAGATAATTGGCCCGGTCGCGCCATAAGAAGCGGGACGCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCACCTATTGCTGAGGAGAGGTGCGTAACCGCAGTCTTCCAAATATCCCGTGGTCAATAGTATGCAGCTGTGGTACATTCTGGTGGCTGGATTTGTAC
+
9=8I(798;9A52=;9I=,';694I(I/'I(67I)189I';I)I0'8;:6I*919:6I.&8:79H'F&19I(695;6575I(;I'56I'7895;;I0'I*66I(76894I'6I(I(24=3;6I(9:;0;I);8I(7:45>:3998I*I*I(I2(G':953>H'57I(9D&57I.'7;9G'5H'87767:66:2;I'789I.&I*886>H'558I(I)7;I1'876I(8567;95I+875G'83?:363794=34556489G'88G'6?4H'96399::767G'/346F&I(65I(79584I(95I):3999I)44?I'7;:47F&I(884638I(I(I-&88:I2(13H'<9I(97649657:57947F&;85;I)36I(6H':7I(9I/':748
@simulated.179
CGGAGCTTCTAGATCAAGTGGTAGACCGTAGACAAAATAACACCATCCTCCCGATCTCAGGCCGGAATCACAACGATACCAATTAATCGAGCAATGAACCAAAGTCGGGGTGTGACGGCCCAGGCAACCGTACTTCTTTAGGCACTGAGAGGCTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGCTAAACTTGGTTTTATAGCGGTTCTCCGAAAAGAGCAAACTACTTCCGAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCAC
+
=I(579I(;378587I'63I)4578I(769672I=,'4I'9:I(73I(6I.'5989<<<I(I'I)I(1597I,43D75I(I+G'I'48<79<I(88E&I'I0'732I?-'664542F&I.&8I)6I(E&:&96I'9I.&6I(;6<;8478I)9I'9I.&8233I'88<7I(I/'67I1'6I'4F'99699<3I,9II2*&H'68I>,'=87;8I'8;A<44765:576<:39I'69>>I.&I1(I*983;656I(8>5475I(I(47I0'5=55::8I'45783I-&4I)I'I9+&79305I)I(79I(6I9+&3746I0';75&I'G'5;I(<66;I(I(=I>,'7G'H'@I(867:85999:;I)88I.&89H'8H'9I'H'79675G'667I<,'I(5I(;75I)I;+&6690
@simulated.180
GCAATGTATCACGCGATTCACTGGCTGTCGGCTGCTCGTTGTATTCATTAGGGTAAGTCATACAACTAATATTCACTTTAAATTGACTAACCGGGCCACAGAAGGGTTAGCCCCCGTGAGCACAGACAACTCAGTATAGACAAGCCTCTACGCGACCACCCGTGGGTAGAAGACTTTTGACGTTAATCTTAAAGAAAAGGCTTCGTACCGTCTGTGTTGCGTAGATTAGGGCTAGGCCAGTAGTCTACGTGCAAGATCTTTACAACGATAGTACTGCGCTGGTGATGGGGCTACAAAAAATGAAGGGCTCAACTCAGTTATAATAGTACGAACGTACCAAATTGAGGTCCCCAAGGTTCATTGTAATTTCACAATTTACCTCTCGTCTCGCTAAGTTGACGGGATTGTAGGGAGCTGGTGCGCGGCTTCATGGAGGGGCGACA
+
4<I'36786373:574H':537I(99;87I)8;5749:I(>;:I'85I(3I.&2I(28486<9I*99I*:7I(879I-&I0'I(758:I)I(I2(I)8<58I(I.&I(;5IG0)%62488594;47;I*75986&<6386;I(5I(25':<7;6:G';I1(66I0'81:E&743I7*&48<6I'H'59I(I/'5I9*&F';H'2=67I'9;58658I)7368895I'8I/'985G'I(6>6>@8166<;;38I(<996I4)5:G':72?6889778;?::I)961;I9*&;5<3II9.(%36I'I.'467I(:=73>I)58I'=673%55I':857I)I.&H':7I(6I:+&H'I'G'9;H'>;I)I1(376I(I-&;I)7786<;485;54I(9H':3?I.&9G'66/I1(96;1I)97818G'5H';<3I(6I=,'9=679
@simulated.181
TGGATGTCTATAAAACCATGCTAGTGCATGAGCCGACGTATACAGACTAGCTAGGGGCCTACGCGCATTAGCGAATGCCCCGATGCCTCGCCTCGACAGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGTACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTCGGTCGTCTGCTCGTCGTACCAAATCGTGCCCGCGTTTTTCCTTATGGAAGATA
+
6I(9586653:I;+&I(6=768<2777748D9G'7;372655:8;:84<7>59I;+&H'85<9;:97I'24D:I(55I<,'9:86I(<85I(6&8;<741I(4:H'9I*I(79I(8885I.&:2I)I'5I7*I'5I'567A:5I(=9I(4:7I)9::I'74:9I)I/'5I(9I+I0'4I1(7I(<I)4=5H'I:+&54<::783;7I(6I(I'=4I(I/';798=66I.'89I(88I':I/'6I(59I'I(85485;7788898I'75879:;'49I<+&1I(7H'97I(6I/'8:57=;I)=E&779899F'96<8H'H'6I.&6I'I(I2(;6697I(:>9874I.&76=445G'I(6I))G'8579<<9959;694;5I'I/'74568I4)4;6II3*&I'I'39I)I)435:
@simulated.182
CTCACGGGGGACTAACCCTTCTGTGGCCGGTTAGTCAATTTAAAGTGAATATTAGTTGTATGACTTACCCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACATTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATACGTCTAGTAGCTAGGTACCTGGACAGCATAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGGAGCGACTAGATTTTTGTGGCAAATCTTATCTGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGTGTTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGAAGTCCTTTGGTGCTATGTCCCCTAAC
+
::;43IH0)&'88I(I.&I)668<I(I+I(I(7779I)I-&I-&:87I*69I(<6I)94686:9G'=I2(7G'65I(5:8I(:874=52I)57464I)4;;:H'588;78<:37<<G':I(I(I(I(91I(I(8<989I(8I)I'2I/'>546*9:67;8<991868I(75I(:I(6599:6<967<5I)5I(6II3+'68;I)694:59<5I1(I(:76876<I(26I'532:7=3I(9;2=869548II2*&=8I(1I0'6:I(8:5959:829I(9555@9I'945>I(6285573786648I(79=H'797669:246G'6I(:6;-7595;697I'2I6)79I.':I0'I9*&8:H'969I.&I)9;82=74I)89I'I)8I>,'7:63;9G'59I'I-&F'7774366:I9+&6I(4
@simulated.183
ACCGGTTCCTACGGGGCTCGATAGCAGACCTGAACAATACGTGTACTTGGGCCCATTACTTACAGTAATCATTTAAGCCTTGCTATGAATCTTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTTAGCGGGATCCGCACGATGTCTCCTAGTTTTAGTCACGAAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTTAAGGGCTGGCCCCGACAACCAACTATTGCGGCAAGTTTCACGGACCTGCAACTTACGTACGTGCTACTTTGCGTCGCAAAACGCACTTGGGTTTTACGAACTTCTGCCTAAGAGCGGACCGAAAGCCCTGATGGTACTTTGAGCGGGGGCC
+
3I(I(I(I(95%I:+&87891:7.8=;;I'86G'7F'896:86448I)I/'I/':H':6I(67;::I(139I-&I'7I+G'7>;<78I(83II1)&H':I'H'5H'55;42B67?F&67;;89H'I'6478-98I(6;4I4)55I(886:199444CI'6:4I;+&7=96787I.'I(798I(I(94I*63H'=I3(8=996:669I/'I(I/'I-&I(6I(I/'I(I1(2;I(I:+&=<5H'I(I(886I(:4I'4I'2I1(899H'8I(876I):I(;?6685749:>=1I2(<:64885I<,&989:8I(I-&I<+&5<7I';I(67:I(5I(8>86I(:I(=I2(:I.&=:97I(:7&I6*7545II3+'I)
@simulated.184
ATGTGATAAGTATCAAAATCAACCCCCACCCAGCATGTAATGGTAAATCTTTAAGAGACCAGACGGGCAAGCCTCTCAGTGCCTAAAGAAGTCGGTTGCCTGGGCCGTCACACCCCGACTTTGGTTCATTGCTCGATTAACTTGGTATTCGTTTGTGATTCCGGCCTGAGATCGGGAGGATGGTGTTATTTTGTCTACGGTCTACCACTTGATCTAGAAGCTCCGCCTTTTGCGGACCTCAGGTTTAAAAGCTGCGGAAGCTAACGCTCGTAATCGGATGATTAACCACAAACACCTTTGGGTTGCCTACCCGCAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCA
+
955:757I(5383?I>,'5:I(IH0)&8I1(5646;6<H'4I(6I0'7=I/'I)1899I'9=68I0'6I)6H':629:647I(5I/'7I(4:9I)H'<I(4I.&I(668:56I9*&7/4I2(I(H'36I(8<8373H'I'&I(G'78G'61I3(7684G'I(I'F'5466;79I.&3I(;9E&99I)7I<+&529359I):<97I(85I)633667:I(62;I(8H'I<,&86I'8I(9<2I(I/'I:+&:5517I(I(53:I'4<>6:;8I'93I)=8<5I(I)I(=6I0';8G'I2(I2(I(<I'<<I0':6:51<877I0'77I/'I)6I/'87I(98>;989I(;I(8>49I1(89I(G'3=9G'9
@simulated.185
GCCGAATGCCCCGATGCCTCGCCTGACAGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAAATTTACCCACCGTTACATAACCCCACAGACGTGCGCCACCGGAGTTGGGCGCACTCTCCGAGGCAGGAGGGATTAGTTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCACAGGCGAGTACAAAGTGAGAGGAAGTTGGTCGTCTGCTCGTCGTACCAAATCGTGCCCGCGTTTTCCTTATGGAAGATAGTGCCCACATGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCG
+
6I(1I*;8I;+&5826I(:57I(4967887I)89I(9I(H'99I*689>I0'6<I'I(7I:+&H';I)9949;8I(37I(7:4I(479I)<9;:I)I.&9F'=I1(I0'8I2(<H'5H'';7:I(I@-'89;778%7:69I(>I(I':7F&I1(7748&;68I+<9I'22G'8I/'6F&5<I/'I'9894:7874699BI(4685668:4I?-'7I(9G':;I(<I.&:55756I(9I(7:67:6I*;=5<I(H'6I/'2I*I(I4)88<82H'56>:77:I/'4=6926I+I'7E&F':5635483:973865:I(I1(999:6I0'85:IC.(I(I)77I'E&:648778I2(4675?4747G'874:<5;77I4)I)795735689I(=967856966I-&8756;99I.&7I':673I)F'G'84I9*&37:I(8
@simulated.186
TTGTAGGGAGCTGGTGCGCGGCTTCATGGAGGGGCGACATTACGGGTTATTAGCAAATATCACCTGATCATAGTGCTTGAGATCCTATTTTCTACTCCAGGTACACCTGATCTTTCCCATTGTTGAGTGACAGGCACCCCTATACCAGAGTCGTAAGCGAATGCAAGTTCGGAGTGAGGTACTTGACAACCGTGGTCGAGTAAGTCAACGGGCCGAGCCTTGTATCATGATAGGAAGCTCGGTCATTCAATTCCACCTATGCCCCAGCAAGGGCCCAGTTAGTCATTCTCGATCATACTGTGGCAAGGGACAAGGTCTCGGGGTGGAATACAACGCATAGCCGTCTCAAGGGGAGTGTAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCG
+
I(>45I0'37:4I)45476I(6I(597I'>I9+&=1671F'&&I/'I(8I):59I.'855:6I)<=47681;6869I(4;791I'87IF/)3378:E&5I(<==5I'79394I.&I/'6I'6I)57<:5;36I):6I;+&:=92I(66639687H'7:4I'890G'8I'6I'73624I'866I)<35I)I)48I(9893&9I(997I(7I.&I':43H'H'8;=<39>?:47I(F'6;37I)643I(7I(I(I)9I(2595I<,'797I)I/'I2(98I)B8555I(=:83;66;833949I'7F&I/'85I)G'67:;I@-'6I)I'677I(7<978<5I':::5:I)I;+&7263&;5I/'59I)787<I)67664=7;92:9648I)94
@simulated.187
CCTTACTAGGGACGCCGGGGGTCTGGTCGTAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCGTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTGTGCGCGTTCTGCATGGACTAATGCGACTAAGGGATCCAGCCGAGAATTTGACGTGACACCCGGCCTATCTCGACAGGGTTTGCTAGGCCATTTTTGCGACACACCGAATCCTCCTATCCCAAGATGATTTTGTGCGTCCAGATTATAGATCGGGCATTGTCGAAAATTCCTTATAAGCGATGC
+
I(I(9;/8I0'648I'II5,'5;9I)969&I(:7I(76E&6:=:846<I(8847:4=9I(<I.&9=I/'5935=94H'1788765I0'57644I1(:3828:9:I(I(:I(349:7H'.877;8I1'1>:G'H':I2(:6:7I1(8%8I(>58I;+&I(97I(;08;993I9+&97I'I(I(7I(<:I(5869:6978I'9;6882I(:6<I(8:8::3=I)I1':5F':;I(574I)I/'792564:69I.'I(I'5<3862;:55I1'I.&9=67I'I'0IH0)%57:65565I,6I(:I(6I(465I.'I(56844I8*&567;<4I(686I(4597:64I1(48I'8583I=,'I(I(I)D7I(<23:D77
@simulated.188
CGATTACGGATAGCCCCCTGCCTTTAGTCTGCGAATCTCAGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCCCTAAGACAAGGCATACGCTGGGTCAATGGATTCGAATGCAATGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATACGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTGTTGAATTTCACGATCGCGGGTCTTACTCCGGGCCTCAATAAGCGAAAAGACGTACCTAGAGTCACTAACCGTGCTCGGAATTCTGAATGTTCCGTGTCCGACTCGTATGTCTATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAA
+
558I'=6I,8<78IH0)&44H'I0'5:%A79<9I(936683785I(79;I0'68I/'I/'7<7G'6G'489479:I*I/'6E&I(A6<6;6;77I<+&7I(9:8I)I(84866976I3(B6I(:I(=I(97I'65?F':846-98.6I(43I'88675189;5884I'7<775I(7I(1I(645I(7I1':78&83947I-&6I.'I'<79I(I(18<65I'<I.'8:955717;I(9F&:I'I0'84639728:I-&99I*494I(I/'I)74I*3I(769I@-'77/689H'9:5<<:4793I)I(495737I(I)I(586I(98G'I(3887I(93868595;377;D96874;;7566I@-':;81I)I-&I'8;E&546I(5I'I-&8:79I(
@simulated.189
AACTGATAATAGGTGAATGAAGGAGGTGATCTTTTTGGCTTAAAATCGTTTGCTTTAACGCCTTAGAACACGGATTTTGCGAAGATAGGCGCAGGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGGATAAGCGGAGCGAAAGATAGGATACGAAGGCGCTTTATCGCGTTGAGAACCATGTGAAGTACACTATTTGATGCGGCACCTGTGCCGAACTTCGTCGTCACCTGATTGCCAACACAAAGTACCCTTGACGATCGCTAGGAGTAGGGCGGCTCCAAGTGATCACCGACTAGCGGCAAACGCGACAGTGACCAGTGCGAAGGCATTACCCACTCAGACGATTGAAGCTACCCCACCGGGAAACGGGATGTGCCAAGGTAGATGTAGAATGTGTCAAAAACTTGTGA
+
I(69<89I'55I'4;H'74I(I(9I(644>8IG0)%I)7E&I9+&9;6I1(8:I/'I(62F&I)66I(878H'9I;+&:6:G'8529I(;8;6II1*&59=86=:4F'8976G'8;57I(5I(I-&II7-(%57I(67I):986I.&;.=9I(6;855I(H':8?I0'369888I'7>9I(I+7::<6I(8C65:684I0'7:369I'96I)8<<8I(5I,9I(77877/97I*9<9I(8I)I)623I/'68;I/'I(76:9;794;37I*8988I-&6I):8I'I)76:8;87G'6A4876<H':I0'7<9;6:9:A3>H':1:6:<I)I(3:G'9I/'43A:964747I):I'4:5;I>,'7I'I/'I/'6I/'87=89I*I(I(<9595;9=7I)384@87II2*&;I);=48
@simulated.190
TGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTCGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAACTTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTCC
+
978I'I0'I(8?5I(85I/'3;9894885I/'I(6I)8I(6:9285:45I/'5I(877;:H'I)95;I'I0'6I2(68863:14I.&1I(678I(6I(7I(6469<F&<95867635;757E&8:I)5:59;8774I(4<:I(8<I(:I(7H'67I-&5;;7;631I(I(636H';I<+&:3&<9267;8I)H'9I-&H'748<675I(9I(:46I1'%I0'9:I/';98I(9:7453884I'7766:9<I-&I'<;IH0)&572<I.'39I(=;247G'5775I(I)I1(I(4I9+&5<6I.&:6I)I'I(605692;I(7;8F'I'I)98;435I)79:I)/9867I'I)64I(7<I(I*I(
@simulated.191
CCTTCCCTGAAACGTGGATTAATCGGGCCTCTGGTACGTCAGTTCTCAATAGCGACAGAACACTGATCTGGGGGCCCAGCGATGTGGGCGCTTGCGCTATACGATAATTGGAAGACATACGTCAAGGGGTTGTCCCGTGGAAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTATGACAGGACAGCGTGAAGCCAGCGACTAGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACACTGCATAGGCACATCCCTACTGGTCGGATGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAG
+
I*G'I0'76I0'257I(6I(I)79I0'I(798I(96D76565I(8:5G'<:314<370I'2:3;9>358II4+'I-&125;65<>I1(::7I(7:7593772448I(H'H'H'5:49597:6:G'I<,&I(8<I1(<:I(I1'58<77:667I/'I):I(49A95I(>56I/'6I(I(I':8:83I(88<;876699<67I(7I(8>6I(H'I(:I(7I/'9I+286565I'=7:<5:;4I)<I(97;1:74'I(:I)8136I+5=I0'7895I(286:I*7;8;I(7I<,'3?34:I(7789699<69858<I(76262I1'5594H'36H'46B:8664I)8H'H'8/865I(946I)967I(76@;54II2*&77I;+&6::;875745698F&67>5I/'8I>,';
@simulated.192
AAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACACGGAGCCATGAAAACGTTCGAATTAACAGCCGACCGTGTTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTGCGTTCACACTGAAATCGATCTAACTGATAGTATGAACGCGTAGTTGCCGTGCGCAAAGCAACCGCCTGGTGATCCTAGCTTTTTCCCATTCAGACGAGGTTGGCAAGTTACTGCGTATTGCATGAGCCAGATAACCCATTGACTTGGCCAGTCCTTTGCAGTCTGATGTACCAATAC
+
I0'<I(I.&87:>46I)57/99<5;6677:898I(;;:3657I(56:;I1(6876:6I(I(I/'I(5:F&4578II2*&G':8I*I(I'::86847I(77<I/'8H'I1'H'<5G'66:97=8I(76:753986I(I.&I(;869I0'987F'36I(;38I;+&74I(08I(I(I)7;8E&66I(6=>I(22575<=8I(=354I(4?I(I)896878888<6>8I'588I'8963885I0':754>45I(77965588.<<I(6:58;94I'8H'258;;6I.':6I'I';G';I(;565I)7@<8II1*&I/'6I(7;99997I(I(I):I(5I(<466;7;9I(0873634F&<858I)I/'8I(754G'I(I'879I(I-&57;38606391;4G'I(86:
@simulated.193
ACCACTACAAAGGAAGCCTCGAGTATTCATGGCCCGTCGGCGGCGATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCTTCCGTAATACAATCTGTATAATGTAAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTACATTGTATTCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGGCTCACTCGAATGCACTCACGAAATGCTGTAACAGCTCGCGCTGCTCAAAG
+
DI)76<66I0'I(I)6I(:=5;;'8I)417I,I0';82I(8I):';68<<94I(H'856546I(7I(:I(I+77I)2I)85I'34I)<36<I(6:;595:473I(I(I-&85I(79:I):I-&:>284249:61<86:69<67I)?4746929I.&;E&:8;;I(H'H'787I'4I)I5)5I(G'869E&:I3(I(0I(5;8695:7I'I)@<64I'I):7I(689I(65>99>;I(;71I2(656I.'47:;9I'5F'9;85F&I*654986377I(;&78I(743I'<5;97I(AI-&459<7G'2I':4F&I':9I'64<;;4;78I0'3448':66I(=1:68957:6I0';;597:I(<82663473@56453I0'8
@simulated.194
AGTAGGTCCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGTAGCCGGCACCGGCCCGGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTCGACAATGCCCGATCTATATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTACTCTAT
+
5356I'7H'88H'I'3AI*I(;I'98767847;F'8I'=F'I(3=4I(I(6=893I(II6,(779I(I*95I(I(I/'I)58I)2556I0':67;F&562;64I(48I(8I'918=I'9E&I)I)I(I6*785:I(:7I/'4:626?6C6?6I)965=59I>,'8;38:I)I0'4;:G'7I';I(;I.&33:68467IH0)%?F'I(0535I0'I0'897?35:8<5I(I(I-&55:68=829I-&G'6;5I(;8I)85I2(G'75446A<E&:39I'<9=686I*84978888;I)68H'6I)I(I)::I>,'499456DI(91H'I=,'5;7I(;;I0'9487I0'6I(I(485I/'98:5?7I'435;5I(3H'I(6/6:&55:9:
@simulated.195
AGTGATTTACGTAGCGAACCTACCCAGCTCTAAGGGTCGGTATGATCCACGTAGGTCCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGGTAGCCGGCACCGGCCCGGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATA
+
67878I4)'<79289;I(H'77I-&960=77I(I/';5I(687688I(8+788I(7G'79I(I);6I(I(8I(363776018I'3I'4H'I(:=7I)G'6:65<I(II:.)&729I(I)9;I'G'I.'I+87I(98<5I-&91:5I(82:806G'<5I(7I(6833I+2I'G'F'I)I;+&4744I(96I1(8692748G'9;:I'2869:5I>,'8;<6/I'I-&496I(6I(;I'<I-&:3667673II1*&4F'G';3:<I/'I/'775957:8:>I(I(I-&968891788I-&G'<33I(:6I(7:I1(I':99:7:7I(856I'7;1877I)3974>8359I(5;I(8I(H'I)89IB.(96@9<46I(67;
@simulated.196
CCAGTGAATCGCGTGATACATTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGACAGCACTAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGAGCGACTAGATTTTTGTGGCAAATCTTATCTGAGACTCCTGATACGGACATGGCATCGCAGAGTATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGGTGTTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGAAGTCCTTTGGTGCTATGTCCCCTAACTTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGCGCTCCGGCTTATCGTCCATCCGAC
+
G'=47:H'85<486;<1794I)2I(I(I'I(7<G'I(758:3I(7H'I(6I0'65598:8:665;966=2I(55I)9I(95:=69&75::56I(8H'6II1)&/82I(49966976I0'I(6654;7CI(28I'0595;:8D;3879;;966II2*&92G'7I.&97I)7856959644G'>8996<I(8886F'8896577656&448I)656G'::8;87:94<I)5I);676;;3;38>=I*7I<,'<4I.&3I/'I<,'78I(7;6I0'I(4=:9657H'::I(I(7I;+&968:58H'8?I(I/'H'5<7;6:<:I<,&<H'/I:+&9I.&:369I)9>877;88644;9I:+&59II3*&987797I(2<;I(878I(46575I(F';I(:6:43H'7;I(679
@simulated.197
TACCCGGTCGAACATGGGCTAATAACTATGTTAAAATAGGATGGCCAGCATGCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCGATACCCATTTCCTATGATCTCTAACGTTGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCCATCCGATAGGATCCAGAGCGTGTGGATTATGAGTTCGCACCTGTGACGGTAAATTTTTGTGGTGAGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAAGACCCTGCTAGGCATCTGCTAACCTAGATTGAATACATACTGAATGGGATAATATCGTATTAGCGAGAACTAAAGAAGGGCCCGCAG
+
C2I2(I'6<:I(7;4I.'3;G'9F'<4586I(I8*&79H'?6I(I(63995575H'7H';5I<,'<<796:A9;=62I':;7I)I(5I)793I(797I(91=;I1'9<5H'<I(8369>6<6<;48599=7?738I'I)6(32;I2(5I.&I)428574364@H'=6I(5=8<I(4I'@36I/'I/'4I(I(48I':6I/'I(4I.&74I)88:6I)97I(:;7>97:54I(9I)47589I'<934E&:5346>I(9I.'II1)&56I(;607<584:3A62H'I;+&86I'29I)I1(7G'I(58473I(=I'6I(8::I(6<I.&8<;56I+4615648;G'I(5548F'7I'87@<:<784I)9I0';=F&9355874I(777:;:I,38I,&7I(I0'I1(4;6<
@simulated.198
TTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGACAAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGCAGGAGGGATTAGTTAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTGCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTCTGCTCGTCGTACCAAATCGTGCCGCGTTTTCCTTATGGAAGATAGTGCCCACATGTCATCCTATGATATCAACCACTGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTC
+
I-&75I(I'9I=,'H'5I(276695G'25I(49:G'348I(;78:I'I.&9I*'8I.'I/'9I0':I(7I(588G'I?-'58577738>>I)8I)I(7=G'I.&8<99366I1'@9B>8I)8I/':I(47I(D78388B642:676I(=58188966I;+&5I(9I'96I(7I/'6486:0I'3I'979996I(:5;4I(I)8I+5I(F&I2(988:;I(53;46:I.'256969H'I(6I(I(6::489<9788;6547H'I3(9856<I,:<2IF/)I'E&72I'I):7<8865I.&36<29578;I(785756896I,I'7'4?881293G'4<=66;8868I.&35:>2<8I1(:I(8<4-6
@simulated.199
GCCGCATCAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAAGCGCCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTTCGCAAAATCCGTGTTCTAAGGCGTTAAAGCAAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGACATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTCCCCCCATTT
+
6H'76949I.'5548;:I';I(68;6;I/'I(82;I(=7:8;4I1(:4<I'I'5489<I(6889I1'5;35I)9=I)45ID/(I0'I(9I'756=E&5853I(29598784II1*&6=;:I):483I(2?5I=,'8I)575I*:6I)I)58H'I.'87I,&7:4I/'I'8I(II5,'67748I(;I(H'7<D&7:C87I(6<7:;I/'99I)86871;::577H'6I/'95<I*3I7*&;5548I'<7I)I(99I)I(5@96746I(67:I(I(:92598<369;<I*:I(6<88I'888I'8I/'I'I(78;9I(8I(865%5:G'6:<76I)8849I)55.:878I2(7I/'53;7845I(4:8I'77I(48I-&8II:.)&9I.&
@simulated.200
CATGAACCGGGTCGGCTATTCGGCATGCACATGATCGTACGCAGGCGCGCGCATTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCTTCCGTAATACAATCTGTATAATGTAAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTCATTGTATTCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGGCTCATCGAATGCACTCACGAAATGCTGTAACAGCTCGCGCTGCTCAAAGATTGTTCCCGCAACTGGCCAACAGCCCCTTTCAGTTGTCAAATCAACATCCGCGTCGAGGCTAGGTACGGTCGCGGCATTCACCCGTCGGAACTAAACGCCAGAGTCTAGAGCAGCCACATAAAAA
+
5859I'I(I/';6I(4;9I(<I,66:5875185738>88:7>4I(98397?62I+:I(5=81H'I(H'63<I):I(I-&4H'I(8;4I)<I1(G'6I);6208574I'I(974:H'H'84I)995I(9770:48I(596I/'974I3(89965I(6I)1:98I(I(5<5426789H'999I(566I'::569I(9I1(<59:>I)6I(8;I)I(66I'=;:878798I/'>88>657I(;9:88:;3=7I4)1;4;7:E&64375784787649:I/'9:H':I(I0'94I(87I'I)I(:55I<,'I0'162I'709I2(88I(<45I);<;:7;<I(;24I(84:I(89=3I)95I)7:I.'47:I(I'5:I.'77I)46;561;55769;1I)65<7II1*&
@simulated.201
TTTCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACTGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCCTAGTAAGGATTTGCACAGACTCAATCTAGTCACGTCCGCTAGCATCGGAGAGGCGACCATAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCCGTGACTACCCCAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTTCTCAGACCTTCTCTGTTCATAAAACTTACGCATGATGCACCCCGGATAGCCCTTCAGGGTAGGTGTCTAGATATGCGAGCGACCGACGACTTATAGTCAGCTACGGTCCTCAATGGC
+
I2(8H'I)767I1'799:7:I(676;:I(;H'G'729=6454I.'<78=7I/'07:884<G'5;<8:4:I0'.;I/'7I(63<1887;H'7:89:75<I)42H'7<I)>99I(477II:/)&E&998I/'187;I(I(5I.';<76787:97I(:5054988688I)879;29923I'986I)766I'68I,6I'78I(896747::;67I(9827H'9<I(=6736H'D&596:I(I*4I-&I0'H'8686I0'92:;2:8I9+&97475;72686;5>335I0'8487;675277I(7:5:86=6363=<96I(7=5277094:I)6I(I(2<I):66I(4I(:I(I3(I(47487<I(I'5:7<7I(87;I9*&6H'6>7=4:77789:I7*&I(95:7I2(H'8:I.&5:H'>3:;:7:68;7564:<765I)47898:I(58959<994657I(7I,98I'4I(9
@simulated.202
GAGCCTGTATCATGATAGGAAGCTCGGTCGATTCAATTCCACCTATGCCCCAGACAAGGGCCCAGTTAGTCATTCTCGATCATACTGTGGCAAGGGACAACGGTCTCGGGGTGGAATACAACGCATAGCCGTCTCAAGGGGAGTGAGCCCTGAAGCATGGTCACGCTGCGCATACGTTCGATACTACCTTACAAGCCGGGCCAACGCACTATGGTCAGCTTATGTACCACCTCCGTTACACTTAGTGTTGTTTGCCCCGGCTGTTTATGGCCGGACACGGACCCACGCGACTTTGTGCTAGTACAATACGTGCATGGTTTGATATCATAGGATGACATGTGGGCACTATCTTCCATAAGGAAAAACGCGGGCACGATTTGGTACGACGAGCAGAC
+
355I'B5687;6<4868I)I(:868I)66)1G'8I)F&I':E&=644I=,'@3'9I(I.&I1'78H'87<8=I(8;9<97::98997;H':F'I/':7I)&I)4:5:I;+&?F'I(764I'88;734;I'9864>H'I?-'65:<95I-&14I'49<7I'839&862;3876;:47I(7=8>=6;7I'I(99I*4I)I1(E&H'68530585I(65485I(47478I)>H'8G'6I(648;I(8448I(3I0'8I;+&I'677I6)9:I'I(F'6395I*3I3(2897737I4)6679899?46I'867;8;9;8I'I-&6=656;6;9I(66:679;::I1(67;3679I'I(<9I(I(II4+'719I-&678<5I-&I(2<:888672;475;
@simulated.203
TCGGAAGCGTTTGCATCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACTGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCCTAGTAAGGATTTGCACAGACTCAATCTAGTCACGTCCGCTAGCATCGGAGAGGCGACCATAAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCCGTGACTACCCAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTTCTCAGACCTTCTACTGTTCA
+
5;I*I(773I-&967:9;G'93931I*4I(I'75469366I1(8376=I-&0:678>3F';325969I0'8:I2(8F'74777596I'A9@:897=I(67G':9H'5;:I(998II9.)&I)758I/':7;4I(E&7I3(:84848:978I(2796977869:I'45:687646I(5=8I(;76I(75I-&=G'8:F&;8618797:78I(8988I):7G'49444I(H'599:E&I(7I/'I/'I(7989I0'2=49549I7*354:77;65346/8775I.':7962>8799;I)>999:85:7>95885I(9296897587G'4I(I'4;I'364H'6I'7I(I.&I(4656:6I'H'99&897G'65
@simulated.204
GATAATATCGTATTAGCGAGAAACTAAAGAAGGGCCCGCAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAAGACGCCCACGGTGTAACGCGTATTACCCACCGGTGTATGTGCTCTCCTATATGGTAGCGACCGCGCGGAGGAAAAGCCGGACTCCTTGGAAGCGAAGTTGCACCCCATACCAGCCTCACGGCCTGATGAATTCAGAAAAAGCCCAGCTTTAGGGTGCCAGATCTTAGTGTCCGGCGGATATGCGAGAGTATTGGTACATCAGACTGCAAAGGACTGGCCAAGTCAATGGGTTATCTGGCTCATGCAATACGCAGTAACTTGCCAACCTCGTCTGAATGGGAAAAAGCTAGGATCACCAGGCGGTTGCTTTGCGCTACGGCAACTACGCGTT
+
7;5I(:<67:3:I(8:<;45I1(56I/'6I)I0'I0'3:<I(844969I(I(:I)<6G'89:I(D9I';H'5I(I(<2I.&I'H'889=I-&6;I(;9/I(67:994G'3I.'8I(I)=2:5355/;479I(:=874I(<4;985H'4776I(9F'I>,'4I'I'8:6G'I(F'I(448I'5I(747I<+&656I(:8I(5285I(F'779<4G'I'<58II3*&2I/'662I.'2I6)=7I(0694;I'499<:I(I(7I(9<98:7=:97;;8H'I)<8;7:551027<:I/'G'443E&I)I)<49I(;I1(I(9495I'77=:295I)7:256888I(<H'7I+I'G'4599926I(9I2(II4+'8661H'7465I(9I(5I'G'99I,&5:;6&8:G'7I(3468<?3I(
@simulated.205
GCCACGGCCCAGCGCTAATGTTAGGCTCAGCGTCCATAACCGTGTGGGCTGTGTTACATGGGAATCCTAGCCTCTTGGGTTACACTTTCGAGACTCACATTAGACATACGAGTCGGACACGGAACATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTCGCTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTAGTGGAAACGGGATCGACTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGC
+
3I(68I(I0'9795=;H':6I):I)966689:6I'48I(G'474;I0':389:H'4946I0'H'8I(3<7I(95I)I-&I)<5::I6)<:4539:<8;4I(697586895;623I(9385I(I'87I(660I(F'G'623378I(I);3885=772;I)82:672I6*695H'4I):9I(I1'I'858I'29I-&554::=992I-&I(7H'4G';>7896;59I/'7I(439=7H'I)2&75I(I0'6I.&845:(6:58I.&:I(7;:I)7I)0I'7481:I)85785698:2:A5I'8:F'96;754;77I)485I(<6G'.I(7G'98I.&8:84834=I'G':<9I(2I8*&946968:;3G'I(2I0'I(;945995I(:I(481I2(I0'47I1'536I(:59465?54I(98<:84:I.&I+:5II3*&8
@simulated.206
TGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGCAACTCTGGAACCCGTTCTGTTCGTCTTGCCATGATACGACGCTTCCATATTGCAGACATTGGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTGAATGAAGGAGGTGATCTTTTGGCTTAAATCGTTTGCGTTTAACGCCTTAGAACACGGATTTGCGAAGATAGGCGCAGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGATAAGCGGAGCGAAAGTATAGGATACGAAGGCGCTTTATCGACGTTGAGAACCCATGTGAAGTTACACTATTTGATGCGGCACCTGTGCCGAAACTTCGTCGTCACCTGATTGCCAACACAAAGTACCCTTGACGATCGCTAGGAGTAGG
+
;53697I1'4I-&4<76159I(9?99I(95466I'8=;8:@5I(?:88H'G'I0'7I(:97I)9879I(3I'5:7995496568H'H'77=I(7676848I)I(4>I(E&=8I(7687:I<,&7H'4=7I-&:I(88;77:8:926I(74I.&87::;H'76I'::I(18I(F'8I(2676=IE/(I)5H'I.'736I.&5?(I/'I'58I(I(<<G'87;I'9I5)9:8I(23;:I(<586IF/(9544965:I'0;:<I)9<59G'7I(I3(II3+'89H'87I(46;3I.&7'7:8I(6;98:I'I(778I/'>5;7&98I)957I'I/'97:58H'7I)85696:I-&58970I(<3H'368:F'6I0'<I'9865<548I);88I(6I(I)542I1'?75I2(I(<7:41567:75I(55=9I*
@simulated.207
TTTATTCTTCGTGAGGGAGTTGACCCATGCAGAACGAGAGTCTTGCCGCTGAATGGGAACATCGCCGACGTTAGAGATGGCCCCAGACAGGCATATCGTAAGTGATTTCGTAGCGAACCTACCCAGCTCTAAGGGTCGGTATGATCCAGTAGGTCCACGGAATCAAGGCGGCTCATGCGTGGATTGCCTTGACTTCCGTAGCTTGGGGGTAGCCCGGCACCGGCCCGGCTAACAGCGGGAGTGCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCA
+
I/'5I,6I)8;:82I0'<3I(64I.&58;9:7I*82=8;7%8I(6I)7798I(4I.'I(58<67F&97:6I)682:98I'I>,'9;749I(85569189I)6796I1(97::69;I(F&87I-&74:598I'I/'<9G'539D59H':6=7I(8I)88G'I)89I(E&;I(262855194I'8G'5I(I(78:I(I(672:?F'II6,(6;8I-&I(;5E&I(I,&I);8I(:749I0'447:I*2;7439I'97I(6I(:798I(9I(I(I(I'I>,':837I(79I/'39<:468I'<96H'94558=I:+&;75;9I)I-&8:;I(8I'9I(6I0'1B;28665II2*&4I)I(;549I2(I1(<25668::96H'I(I0'76;7653596
@simulated.208
ACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACGTCGGCTTCATGCACTAGCATGGTTTTATAGACTATCCAGCCACAGTGCAAACCGATGTACGCAGTCTAATGCCAGCCTAAACACGCTTGACCCGCTTCTAGTCAGGTTGCTGACCTGGTGCCTAGTCGACCCGCTACACCCGCCGCTAGGGATTAAAGGCATCAGGGCCATTGAGGGACCGTAGCTGACTATAAGTCGTCG
+
584G'8I0'9H'68I'45I-&::7;46=I2(I(76I'I)4I(=7864:944;I:+&I(861F'5H'6I.'?I-&I-&6H';I0'I(9563I(52:I(068G'54I(07<<:8I)5I'I:+&4I(D&8?I3(725;I(6<I(I(:I(77I(>:98958I(<5>I)9389IA-'76I)9I(66I)87<76=85H'I=,'99=<09847977577<=89I)5H'3:87477:65933I(I8*&1<;968-5;I)<6I(1;69:76I0'G'988:9:64:5<'74I*65I,37I(5I0'45585I(6:I4):9I+46=8761H'I'69857I)<I(;<I(0<95722I-&5@52:5I1(6I(5693I1(7I(I.'I(74<;;I0'I(;I'47I.&1I)86999=665249I*:;737:5
@simulated.209
GCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCATACCCATTTCCTATGATCTCTAACGTTAGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCCATCCGATAGGATCCAGAGCGTGTGGATTATGACGTTCGCACCTGTGACGGTAATTTTGTGGTGAGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAAGACCCTGCTAGGCATCTGCTAACCTAGATTAGAATACATACTGAATGGGATAATATCGTATTAGCGAGAAACTAAAGAAGGGCCCGCAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAAGAC
+
:75I(9I):2I?-'39991948:699I(:96I(I':I(55AG'4?5I*;963I1(5;4I(7I(16554:>7699:628299656H'I*6::8I0'5I/'F'6795865238I(87I)%;77:I(9I)869I/'I0':H'G':4H'91I/'I(7I-&33I(6826I(<:I(4333:8847I(5I'3685(7G'6858I(999978H'8I+IE/(72I(<389758:7:58<I(I;+&9:I*<<I(I4)7I)I(;;5-3I)5I*3I(895I(;8I/'7665;F'89449<47I+G'46;7I(+6I(66444735:I*6I.&73I(/67:88>I(560899I-&9:I.&6I)I1(I.&9;<I+<7;6;:I(I+:I(49H'6;8I(3<H'2I(6I)I'49I.&E&I(336
@simulated.210
TACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGATTGCATGTGCGTTGCACAACCACTACAAAGGAAGCCTCGAGATTCATGGGCCCGTCGGCGGCATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCTTCCGTAATACAA
+
4;96699:I(8I(<6H'275877:65828I;+&42I)I)I(H'I(576737848I(4H'I(:3I(9I'96;I(I(17H'2I0'46;52H'3489:3:19:I.&8I(6F&587696758;:I(<:<I-&683I'78;686G'874I'G'4I*167I)496944668H'5=36I(I*9<967I0'I'H'6I*667:94I(7::I/'I.&:6:I(5I):;3<;;;:I(I(997676H'9I(:I(I(6;I'9I(95I(<9I'449/I(1:489::82<G'I)I/':5I(=74I(7I1(7455769957387634969>I(76;;8886I0'8I)48:9I*E&G'99>I'5DI/'7I'I'346I(4I.'I(8I)678/:773H'I'77==H'F'96I(189I+
@simulated.211
TCGCCAGGTGGGTGGTGAAAAACACGTGGAGCTCGCGTTCATTACGCTGAACAGTAGTCATTCCACTAACGGTATCATGGAATAATACTATTGCGAGCTCTTGAACATTACAAAGGGCATGTCCATGCCCAGTTAACCCACCAGTACCAGGTATCCTGCTGCGAATGGTCACTAGATCAGCCGTAAGGTGCACTCCAGAGTGTTCATTCTCTAGTCTGCTGACTACCAGTATTGCGACGTTTCTGGCATGTTCGAGGACAGAATCTTCCCAGCTAGATTAGGTTACCGCCGCTTTCAAACTCATTTGTATGCCGGCAAGCAGCCGTATCAACGTAATCGCATAAAAGGCAGGCATCTAATTATATTGCATGGCATTGTGTGTCGCTCCTACCTTCGGTCACTGCT
+
2&1I(7I'3I0';I)76II1)&62:5>I(44798514I*58I)74:5;8I)25<7;6;6=I(I(;5:H'5I)3;9:<1I'I'6I(7>76=I(2;839616I'7I,8=I(99I.'I2(95:88I(495I.&62I(I)I2(5I(42=:I(4H'<29H'4979<58I(>I(;82598885559H'67I)I(586:<4I(348;4<I'/6I(28=78466=:4:77966I';5<6H'5487:9I1(4=H';597I'84;H'&892I'<;H'I7*971D9::F&8G'I(6I)3H'59I/'7I0'6894I/'69996I(I*5F&55<9I(5:879I(57;I'092=;5IE/(I(<7I'57974I(G'28;H'7:5:I(7:I)688:964>9DH'46I(I(;I'<6;<6719
@simulated.212
AGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAAATTCGGAGTGTGCGAGAACTTCAATCAGCTGTAATGGTCACGAGAAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATAGTTGCTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACAGTAAACCCGCCACACAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGACTCTTTGGATACGGGATCGGAATTGGACGTAAGTCACTTCTTATCAGCGTACCACAGGGATTCCCAACTTGACTGTGAATAACAGACAGGTCCAATTGGCGGGTTA
+
<<:5788<7648;9789<877I/'F&::9=H'298I(I.'I'5I';<99;:7859F'3I'6G'7673-=3&I(5I(9:;;894II7-(%55599<88I)I(8F'6;6;967858:5I-&:23;I(8679&H'94I,77I(I-&547:5?8:6I(I(6:43:45:79=;4I/':I'65H'7779I(1478770I)6I(;6I'4=9::15I0'I6);I(<878665:8I(98I/'I?-':8<894I/'I*6I(I'I)57:9:988I.&E&=<77I.&6;5F'I(E&I(6;72I)74<46G'5I,556796675I(=88I2(6G'I.&I'4I);86::61E&=H'46;<88I(6H'I(I)I(6I3(I(:
@simulated.213
CAGACGGACAGCCTTGGTACACTTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGTCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTGGTGAAAAACACGTGGAGCTCGCGTTCATTACGCTGAACAGTAGTCATTCCACTAACGGTATCATGGAATAATACTATTGCGAGCTCTTGAAACATTACAAAGGGCATGTCCATGCCCAGTTAACCCACCAGTACCAGGTATCCTGCTGCGAATGGTCACTAGATCAGCCGTAAGGTGCACTCCAGAGTGTTCATTCTCTAGTCTGCTGACTACCAGTATTGCG
+
96568I'7658I(I)I*8959(H'H'5<75293I5)97I0'6I/'I'I)5I'7F'73863;25I2(966)276:I8*&9I(<I(;77I4)7446456759I(8;I(62959:6G'43:I.&7>7>5F&5I(8I0'7I)76II3+'8=878I'<66869/8H'8:I(5769;5I(79:746899I(E&<:3I)7I'5<>376I*G'8F'73=27I'96>69:66I(5I0'5;G'=<I1'I0'5898<I(848I2(>5I(I(I-&6I)58:5I)8I(79;G'8:64<44I(8I(978857:?:2=9I*74G'I);=77:5I'6:8495I(;8I)09:83685=949756;8I(6689I(85;
@simulated.214
AAGCTCCGCCTTTTGCGGACCTCAGGTTAAAAGCTGCGGAAGCTAACGCTCGTAATCGATGATTAACCACAAACACCTTTGGGTTGCCTACCCGCAGATGTATTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAAATTCGGAGTGTGCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAATGATCGTGCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTTATCCAAATGCATGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACGAGTAAACCCGCCACACAGCTCGGACTTTAAAACAGCTGCCCAAGT
+
I'985I'7I(I:+&;;I(5I(>8;I'I,I9+&5:738F'I(455I)863;:98I)37D7;=9I'H'I'25I0'84I)I-&I/'I(:I(67I/':>78887;8I,84I/'H';I.'8:I(8:;<976I'7I(7286I.&79I(I'603H'5<;44:667666:976::4::I/'I(4548I(7>8I)I/'I(;I)9;876:5:84I)4I)4G'228:658I'4H'6788::6II6,(59<36257G'I(3H'8:8<87994365I/'97:;I(:686I(3;I.':9I'I/'8?86787=/I)I'637594566879:I2(2I(77I(5889I(8;64;22I'7I(45I'<=16&797I-&I6*5I':=6:>:047H'86I.&I;+&999??3I-&I(79
@simulated.215
TACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCATCAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAAGCGCCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTTCGCAAAATCCGTGTTCTAAGGCGTTAAAGACAACGATTTAAGCCAAAAAGATCACCTCCTTCAGTTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAACTGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAG
+
681I/'58:I)G'9I'8;8I'274655<9H'2I1(9H'3476I(66H'2;764I-&868;5<D&5G';6:96I/'I'5=6I(88:696I.':67I)I'=97:4I'65;6I1(;956I)78I)33IE/(I-&G'9I)8<39I)6;28I)44>81789II1)&5967I(6;5:I(:68I>,':I'<4;I(<9I(I(62I(I/'6(:I,8@:I3(I)8I'II0)&:9786I)4I)I(85*I';7H'4:I(35866I-&:4H'=<>;49;8995I(AI/'89:I(7I=,'2;8;5I'57I'I(96H'I'&69::7;6I)6;3I(I(:487;668:583I(2H'5:9=I*686I(:I-&D&F'249=I':I(9::<=H';6688I'8659I'8384777I.'7I2(55=93;7I'>3
@simulated.216
GATGGGATGTCGAGATGACCAACCCATCAAACCTTGCAATTAGCGGTGATTTCCTGGGGAGTGAAGCGACCGAAGTTCGGGTGCATTAGTCGATACGTGGGGGGTATGCTGGTAAACTTGGACAACATGGAGACAGGCACTGCGAGCCGCACTTCGCCTCACGAACAGAACGCCCGTCTCATGATGTGGAAAATGGGGGGACCCTCAACATTACTCCATGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGGCAACTCTGGAACCCGTTCTGTTCGTCTTGCCATGATACGACGCTTCCATATTGCAGACATTGGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTCGAATGAAGGAGGTGATCTTTTTGGCTAAATCGTTTGCTTTAACGCCTTAGAACACG
+
785I1'<=89;<8828::I+I(I-&539I.'G'I'79I(I'9:9I(>65I.&G'8I7*&56:6I'7:>2G'8I(:E&7I.&2656I(95:9&566<8:II=0*'394476I)6I/'9I(I(68H'889I(57896I(536728868I(7:55I'73I)743=9I(666I(88I0'688D89624447I)I@-'8II;/)&.I0'8;I(17H'>::I(:9<94;3I-&9I.'8488574I(=279F'=:8:7I(5=578D&5H'7818I)I(I0'8I(;9:I)6;59I(3I*7@:378495978G'I':29I(7964;14I(I(48I(H'=5I'49997I<,'<I(457I/'9F&459;78:7419I(97I0'64987I(<6I(9'3I(:6I(I'2H'9669:II2*&I(CCI.'665I0'89I1(E&46I(I*;;I(<;4<
@simulated.217
CGCTTCTAGTCAGGTTGCTGACCTGGTGCCTAGTCGACCCGCTACACCCGCCGCTAGGGATTAAAGGCATCAGGGCCATTGAGGGACCGTAGCTGACTATAAGTCGTCGGTCGCTCGCATATCTAGACACCTACCCTGAAGGGCTATCCGGGGTGCATCATGCGTAAGTTTTATGAACAGAGAAGGTCTGAGAAGGGCCAGGCGGACACCTGCCTTGAAGTGACGACTATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCCTACGCCGCGATAGACAGTAAGTCCATTTATGGTCGCCTCTACCGATAGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCT
+
C86I'79868<9I)I(8>;67I(9I)8/I(6629783I/':6999:I0'4I(85=9I0'4I'I/'I(48589I/'G'6G'53I.'7E&8?558677889;I(3<66>;H'36687;5;972;895496>I)6>I/'77I(I1'1268G'I8*&9:=:725<6568I(7I8*&46:G'56:36I+I(;89<62H'I.&I(9F'2I(>>7I(:3F&I(3I'4857749:&3:I'98783699966;6;9H'467/49:5705I1'394=6485569:86965I<,'394578:I,7446I)I1'I/'6I'H'9>64I'I)976>5I(34I(;68:I(68246*982688I(54I':I2(73I(894I(745)I);96+286473H'6677=;69<84F&;561887<;8I.'7I';
@simulated.218
CCCATTACTTACAGTAATCATTTAAGCCCTTGCTATGAATCTTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTTAGCGGGATCCGCACGATGTCTCCTAGTTTTAGTCACGAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTTAAGGGCTGGCCCCGACAACCAACTATTGCGGCAAGTTTCACGGACCTGCAACTTACGTACGTGCTACTTTGCGTCGCAAAACGCACGTTGGGTTTTACGAACTTCTGCCTAAGAGCGGACCGAAAGCCCTGATGGTATTTTGAGCGGGGGCCGGATGATCCTCGTAGTCTTCAAGTACAATCCAGCCACCAGAATGTACCA
+
I-&7I(66I)52;77G'4;7I1(I)4I0'I(65;274I(79II2*&I(8I)I(3I*6688558;6I(531965I'H'67>8264G'57:I/':5I(28;<4:5:927I(848I9+&9964921I,H';3:G'I(:8I(99H'5I3(:26757:>8I.&I(I0'I0'I'9I(I/'G'I0':5I+I9*&72:I*H'I(592E&97I(7G'4I0'886I(7G':36I(7I(85<@77976546<I0'==868;8I9+&=518:(I(I.&I?-'5:6G'6I(;64I+5I(;=17I(6I(.I0'=I2(58;0I)83I8*&5;<7II1)&I(G'86860I)D?>;;67;I)?I(5458I,=H'95I(5I(84I)4:98I)9
@simulated.219
CGAATAGCCGACCCGGTTCATGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGAGGAACATCTATGCCGCCGACGGGCCCATGAATCTCGAGGCTTCCTTTGTAGTGGTTGTGCAACGCACATGCAATCATTCAATTACATTCATCATAATCTCCCGCGAAGACGCATGAGCTTCGGCAAACTCGTAGTGACCGCGCGCCCTGGCATTAACTACCGTTATCCAACTTACTGATACGAACCGGTTCCTAGGGGCTCGATAGCAGACCTGAACAATACGTGTACTTGGGCCCATTACTTACAGTAATCATTTAAGCCCTTGCTATGAATCTTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTTAGCGGGATCCGCACGATGTCTCCTAGTTTTAGTCACGAACCACGC
+
57I(7:9I'86I/'I(F';0466::696I)7277I(73H'6:I(4G'98G'H'4I(3I':85:59I(H'A69:6753I(;I(:;8I.&I.'84=I'637;:9I(:I*I*I2(;538=I)I(:5:5H'7;6:888:1I(953I'5I(H'88;I(9:46=4I(;:1I3(647H'85878<89398I)1I):I1(:6787857><I(56986I-&8G'37G'I)855I(4I(;7F&I)8E&58:43;=;;I*I)I'I'I)98I8*&2:5766886897I'6;F'<I';89;88098I(I0'I3(6F'66I(:57:7I'295I1'I+9I-&I)7762;<I):=IG0)%I(4H'F'7I(57888@259G':@8926I(I(8268469I)>73I/'66I'38854=7655;I';;0I9+&5846377I,I)967:
@simulated.220
GTCCTTTGGTGCTATGTCCCCTAACTTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGCGCTCCGGCTTATCGTCCATCCGACCAGTAGGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCCAGAACGATAAGCCAGTCGCTGGCTTCACGCTCGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGATCTATGTCTTCAATTTGATCTGTGCTTTCCACGGGACAACCCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCC
+
45I(I/'G'77867:88I9*&7I'6I7*&3I1(7759I)89764429=9378I;+&55II0)&6:34<7I(8.7G'8::I'15877I(I*8I'59;97G'5:H'99F'5699I/'86>=9I(9646:7:5;:4489I)4?252I8*&;I)6483I(984:I(486:I-&=4I(75<=I(6F'97:<896I)6H'789<69&;8I(653;98I.&=I1(4I(5I)I(E&947I'6I':8:1848;66=58G':9:96F&I(G'5I,682D8754:H'5I(I0':79;;674:I/'I(52I.&67F&I:+&G'8987685:85I)E&I)I*;976:298;89;I(984I-&;76;4>4:I0'II3*&
@simulated.221
CGCTTGCGCTATACGATAATTGGAAGACATACGTCAAGGGGTTGTCCCGTGGAAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTTATGACAGGACAGCGTGAAGCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCAGTTCTAGTTTCAAAAGTTAGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTTAATCTAAGA
+
8;7H'89683986:84;I(I(I(I(:5:54664>9I(I;+&I(<4I/'5>I(I1(6<5;5657;I0'G':I(54459I*488I/'6I)I(H'8;:92H':3;:5?6<=8637G':I(<77I)I(I(0F'4I.&9I3(87897:I'757725<4I);G'97:2958I(9I(;631I(77I-&5678G'8555I)3868I(6I8*&<7867I(:4<1559.6;95?3I)7684=I2(57?6I(8<H'87I)47>:7I(2E&I(70:99I(:60I'72=I+6855:7II1)&:6I@-'753?4778;68<4(I(2>96I1(8I<,&5I)9I7*6=5<6556I(I.&I'6;I(>76537I>,'8I(I(:;I'936:333I(I,898I(62
@simulated.222
ACGCTGGGTCAATGGATTCGAATAGCAATGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATAGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTGTTGAATTTCACGATCGCGGGTCTTACTCCGGGCCTCAATAAGCGAAAAGACGTACCTAGAGTCACTAACCGTGCTCGGAATTCTGAATGTTCCGTGTCCGACTCGTATGTCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAACACAGCCCACACGGTTATGGACGCTCGAGCCTAACATTAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTC
+
:3728I1(37F'4E&=I(73I(:&6:I)764:78888H'24G'838166;476498I)95547I*6I'7I)356I'4I2(9;665594I1(4I0'I):59I(H'8267;I(:I3(425736654I)5I'<I(I1'647596698I/'42I(26=G'I0'I)67I)6I'763I8*&879<92I'=6<9:6348;I(H'9;4757I'I(F'67:I'82I(G'463:I':7;264979;584I(853551=9585I:+&9:;6I(I.&I(2:D&90:I(7I'I.'=875I(49273I-&6484I)I)69I+98528&5:6I(9H':8I(795698I1(G'97I'6:576I(;H'I(3543664
@simulated.223
AAGACCAAACCTGGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTAGTAAGTACACTTAAGTTTTATAACAAATGATCGGGTGTATAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATACCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTCGTCTGTAGCTAGGAAACATGGTGACCCCGAAAACAGCGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCATAGGGGGGCTTTCTTTTCACTCAGAAATCCGGCAAAGACTACGT
+
I(9<F'I1(I'8I4)664H'903;/:7I)I'E&77I)II0)&371<I'85I'I2(H'I(6936>:I,&<577I(87;55<6I'79797:7=6?9:589(;I(505<;<I,I)5I:+&4:D&3I0'99:3;I1(4:<:6;I.'8;57869I'744I.'797<82626<76>9I'77:59>%I/'2G'69H'564I(5/4I(574:9>99884:5:885;:I.&889I.&77I(76>;I)969482:I/'I9+&:I)931428883576I(I.'1<4I(;58I=,'5ID/(3907C44:F'8H'6457>65I(6I/'6<:976I(87987985645=4<6I/'8=4I(;7I(I'9784650979<3II;/)&6I1(:I<,&569;796I.&6I(G'5I0'4;:9567;
@simulated.224
GGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAGATCAGGTGTACCTGGAGTAGAAAAATAGGATCTCAAGCACTATGATCAGGTGATATTTGCTAATAACCCAATGTCGCCCCTCCATGAAGCCGCGCACCAGCTCCCTACAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGGGACCTCAATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCCTTCATTTTTTGTAGCCCCATCACCAGCGCAGTACTATCGTTGTAAAGATCTTGCACGTAGACTAC
+
I(I/'9E&779H'94;2:I)8:H'I*859I(42;H'<:95:I'5I(7H'972G'76=H'6773:6<8I'7295I7*&<:I)=7589539I'6I)0I/'I/'66677I(8:36I(;I(7846<II0)&:8I'78979G'7679;>;69:59I(@439?I0'967I(6I(I-&I(63889I9+&:G':4=I(<I(88746I)89:8I0';5:I(7I-&4::I(:I(;3868785;<49I(:I-&I'158I4)I)>3I(6;I(I(F'I9*&7I(98I*I.&I)8778I(9;8969H'56E&48:3@I(978I0'I)44II7-(%8498I=,';794D&:<9:9<76745725?I(79I/'6569I'5:>799:4?8<6;
@simulated.225
ACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTACTCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACACGGAGCCATGAAAACGTTCGAATTAACAGCCGACCGTGTTATAGTAGCGGTCACTAATATTGGAGCGTATGAGTCATTAGCGTTCACACTAGAAATCGATCTAACTGATAGTATGAACGCGTAGTTGCCGTGCGCAAAGCAACCGCCTGGTGATCCTAGCTTTTTCCCATTCAGACGAGGTTGGCAAGTTACTGCGTATTGCATGAGCAGATAACCCA
+
6287315I0':82G'958<745I3(:89::7I0'885=5I/'6I)=7I;+&6I(I/'48:355I(957:6<88777;56;@I(8;;8795I)7628I.'78958&9I'F&I5)I'8;I(999>II1)&G'5:I(I(I'9930988I'84;I.'7F&I/'D76I';569777I'565:5;9=0G'I.&I(968:I0':58I'92I(:39I>,'75H'75I(I(I'8<7F'8:F'625I(@727389;I':79%2I(7;I)I(2164997=76653I(&4>6I'58=39;*:I0'749;535H'>3982898997I':775:74I*8I)7546;:I.&96H'I(6I)9I'8=64I*8355II0)&I-&=I)8016871G'I'G'4I(;I(;869;743H'>=7:=;9B7;76F&I/'=
@simulated.226
GCCATGCCTCGTAGCCTTGTGTGAGTGCGAGATGCCCACCATCAAGCCCCACAGACAGCAAGGACAAGGTATACACCCGGGCAGTACTGGATCCATTTAACGGCTAATTGATGCATATCCCTGCACCTTTCATTTCCTTTCTGGCCAAGGTGTGCAGGTCAAGGTCTGAAGTGCTGGAGACCTTCAGAAGTGTTAGTTATTCCATTCTATAGTACGAATGATAGCGAATAGTGGTGGAACAGTGCGCGCGAAGGGAGGCTCCACCCGGTAGTGTCGATCAATGTGGTGCCCGAGTGTTTCATGGACAATCACGCGGAACAGAATCGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGC
+
@I(56<I,5;7:79G'G'495:65::09657758I1(:I(9;7I(@I?-'66767498<I'I(49I'I)782238I/'I-&;?63148I(79I'7I0'I(&I(96F&I':7:7536>2I3(66:8I'I0'::I/'I(I0'9>I(I(I)I(88:8.6I(69F&I(9987I(46973H'8D8E&I(57;H'7<2I)36I(:I)H'=I*8862863;95I)<5859857I(8464I(3H'I'62:48399567G'I-&7I'65I(:I1(I(8:87@37=565H'86>I(97I0'95;97I.'896I';<I(795<79I(I(B96I':'4I(G'5887;I)7>7I(<67<65I)G'I(534I)9488774I(H'I(65I0'799I7*3
@simulated.227
AGCAGACGACCAACTTCCTCTCACTTTGTACTGCCTGTGCGGGCCGGCAAATCCAAGTAGTTAGAGATGGCGGCTGTAGAACTTGATTCTTGTTTTGTCTGTCGCAACATGTAGACAGACTTAACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGTAAAGTTTGCCGTTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACGTCGGCTTCATGCACTAGCATGGTTTTATAGACATCCAGCCACAGTGCAAACCGATGTACGCAGCTAATGCCCAGC
+
55556:>89I'I(7I(I(598969I0'7461<:I);6578I2(I(I)9I2(8I)I(;946G'3<:8;:I(6I';9949=I+7I*94I(8I'5I<,&:44::7886H'87:57574686;:H'H'47I)9I1(9I)95I(9AI.'55<7777I/'I(59I(I(6I)8<8:7146:6I9+&I(697I(8H':I,9I0''I2(4I)5I/'I)639:I(4;;H'467I)7:I(5432:?I'9I(I?-';E&I(83I1(865<I)95I(I(7I)<9I'97588:6I(298I':997I9*&95I':I'88I)8749976;I'I=,'8=9767<978;7<8742:7I)=I(859566745;976I)I<,';:515::8I(:9I(4895395I.&I(4<9857;;856@7I);<I.&:88
@simulated.228
CATGAAGCGCGCACCAGCTCCCTACAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGGGACCTCAATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCCTTCATTTTTTGTAGCCCATCACCAGCGCAGTACTATCGTTGTAAAGATCTTGCACGTAGACTACTGGCCTAGCCCTAATCTACGCAACACAGACGGTACGAAGACCTTTTCTTTAGATTAACGTCAAAAGTCTTCTACCCACGGGTGGTCGCGTGAGGCTTGTCTATCTGAGTTGTCTGTGCTCACGGGGGCTAACCCTTCTGTGGCCCGGTTAGTCAATTTAAAGTGAATATTAGTTGTATGACTTACCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACATT
+
55;;I(<A985>4I'777;I-&296E&6I/'3<?I)8I'58<6;;4956;7I)5I-&I(:44I2(I(:5H'9=I'I(I)I<,'8I(98I(I0'I)558<I*978783H'<3I)6=<3:I(>13I0'I(5;II?1*'6754I6*;6<4I(9778564:76<4758G':9I/'1589I)71845:6=77:34=G'I(696I2(4I'42?7596I(466798>I)4:;<E&:&I(I:+&6I.'C;5G'H'4789I<,':88I(767I.&;9I-&<I)6:884697G'=I(9585:894656I'7178<8844;49II1)&:6I(I3(I)7497I)I/'I(I(;597H'I3(I2(93=I(7=I)77I(4597896I(8I,3I(86F'754I)9=55:99I(96>69H'7874I(7;9958;5;794I(
@simulated.229
TTATGACAGGACAGCGTGAAGCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACACTGCATAGGCACATCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAGTTAGGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCAAAGAACACCCCGAATCACTATGCGTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTAC
+
I(4;4981I)14696247I(7F&:7;?974I(8I(9924I(99I.'7:<<I(@687I)=:7;I(9I;+&27=97I)9;5286:99773:8I(2?6:<I,945<H'48I(:9H'8:6:6I(4I(I'99849I(675I)5<<I(53:740IE/(64I9*&8865:64798687I(6944I.&:I<+&4I(5I7*&:7836467H'I/'F&92I(:4:867I9+&1H'I'95E&5965486I'I1'469I);7I6*I.&6I,8;I8*&9I)7678894:5&:91I(1I(62;696=:58I(77:I(5:7>853:7A54:I(83;7I(69>7:;I)663:956869F'7=I/'9I'88II2*&933754<;8:H'7?8
@simulated.230
TTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTGCGTTCACACTGAAATCGATCTAACTGATAGTATGAACGCGTAGTTGCCGTGCGTCAAAGCAACCGCCTGGTGATCCTAGCTTTTCCCATTCAGACGAGGTTGGCAAGTTACTGCGTATTGCATGAGCCAGATAACCCATTGACTTGGCCAGTCCTTTGCAGTCTGATGTACCAATACTCTCGCATATCCGCCGGACACTAAGATCTGGCACCCCTAAAGCTGGGCTTTTTCTGAATTCATCAGGCCGTAGAGGCTGGTATGGGGTGCAACTTCGCTTCCAAGGAGTCCGGCTTTTCCTCCGCGCGGTCGCTACCATATAGGAGAGCACATACACCGGTGGGTAATACGCGTTACACCGTGGGCGTCTTAACC
+
I)8;<49><4I(1285I)>/I)I)56898759;9879H'165I(5595;7;I.&7:2497:I(76<938=6856I)8897884I(4I(::46;'2I4)07I(I'2I)=I'7589I(236=IB.(I.&;G';192A47I(F'F'7I(:G':7A39689I'0746647I(87=2I'I-&7I(89?F'I(I)881I)I-&976834661:928I*I)946;:7:4704:;H'1I(G'73;;9G'258;5I(7:I<,&8I-&766I/'4II3*&;73F&I)<4;<>I(I(62&75I(94I)796I;+&24;I(9I*557I'I(I)I(9:4I)I'6I:+&I(4G':<:7I(6=6835I*2;99<I(6:6:4398;757I'I*5I/'6H'974687E&292I(:4I/'7545I*I(I(
@simulated.231
GAGGCGACCATAAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCCGTGACTACCCCAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTTCTCAGACCTTCTCTGTTCATAAACTTACGCATGATGCACCCGGATAGCCTTCAGGGTAGGTGTCTAGATATGCGAGCGACCGACGACTTATAGTCAGCTACGGTCCTCAATGGCCCTGATGCCTTTAATCCCTAGCGGCGGGTGTAGCGGGTCGACTAGGCACCAGGTCAGCAACCTGACTACGAAGCGGGGTCAAGCGTGTTTAGGCTGGGCATTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAACCATG
+
;9I'575I)89I1(<I(8;I(8636789>378H'7:=2I)76H'6:6=8I'I'9382I)I(7I.&I,&H'6616I/';::9:29I@-'79549;77:878:9647I0'<6:7067;4:6I'77696396;8@<759I(8426<:4984I(:I(G':6I(386I(4I)6I'I.'I(8?<4:6I(G'49587I)57>I7*7H'8;;<94;89866I6)I);647I,H'54I.'56I'8668048;54866:6;935H'897;93I':479=:84:891H'7I,29I(:I)I.&595;7I'I1'I(7I.&7634I*?I.';693:7I.&:9;>496I)79H'7H'?7887H'I(348825+6I)86I<+&79I'<8565I.'6I(72I0'99I(;879444>83294I(I0'8754:66I(4;I(>;958288I7*I)792
@simulated.232
GCTAGTACAATACGTGCATGGTTTGATATCATAGGATGACATGTGGCACTATCTTCCATAAGGAAAAACGCGGGCACGATTTGGTACGACGAGCAGACGACCAACTTCCTCTCACTTTGTACTGCCTGTGCGGGCCGGCAAATCCAAGTAGTTAGAGATGGCGGCTGTAGAAACTTGATTCTTGTTTTGTCTGTCGCAACATGTAGACAGACTTAACTAATCCCTCCTGCCTCGGGAGATGCGCCCAACTCCGGTGGCGCAGTCTGTGGGGTTATGAACGGTGGGTAAATTTGCCGTTAACTCATTGAGAACATAACACCTGTGATAACGGTTTTATTGGCTAAACAGACCACGGAATGGCACCGCTGTCAGGCGAGGCATCGGGGCATTCGGCTAATGCGCGTAGGCCCCTAGCTAGTCTGTATACG
+
=758<3;5F&>6562:68:H'I/'3::<8872;G';764;7541I,;8166;8I(I(99I(I(IG0)%75@I0'95177I0'I)62;683<;8>7=6658I'I(;H'I)7=;4:6I0'6836;;I(86;83I1'F&I(5I0':I*I(8879E&79985>I(3I(::4:33I/';I)2;I(6I)9I8*&=77;4268;I(7;8::973:<666I)I(1;I(;I1'6I(97I(96I0';6597<8I1(I'85I)G'4I)259572896:I:+&I(4<1F&2G'7I/':I.&I0'3I(5I,E&:<;9F'95:H';6:I(;8G'712764I(3I(I:+&6F'I(23I0'5485E&6;I(I'7I(76I'9:</866I(744I(6<61I<,';:I(4I'87I'54488<8=I(I9+&;4535879764873484
@simulated.233
CAACGAACGACGCTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTGAGCAGTGACCGAAGGTAGGAAGCGACACACAATGCCATGCAATATAATTAGATGCCTGCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGAGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGGAAGATTCTGCCTCGAACATGCCAGAAACGTCGCAATACTGGTAGTCTAGCTAGACTAGAGAATGAACACTCTGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACCTGGTACTGGTGGGTTAACTGGGCATGGACATGCCCTTTGTAATGTTTCAAG
+
;I(7=I)9659<;957::89I'570I(I(=8G'787<<3I):927979:::6I)9875H'664767:=58I'8H'I);>I(I(=77774547I*=8I)5663I(685I)F&99364I(83I(II1)&<76689I*38:G'2:9:5I(;666H'6I)F';0;<5I1'67:<I-&9I/'48I(8I(6I(I'8I(>91I)62<I:+&H':6I(37;I);<9I'2569I(8<I/'94:345I'5449H'>5648%599&828665772I'89I(4:;408I(979567I'E&84I)495;;44797<:I(7I(8>4;:88I(;84I(:I'9962I(6I1(H'I(67I1(886I(09776I5)I-&<:I(8:I-&7I(4
@simulated.234
CCCTAGCGGCGGGTGTAGCGGGTCGACTAGGCACCAGGTCAGCAACCTGACTAGAAGCGGGGTCAAGCGTGTTTAGGCTGGGCATTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAAACCATGCTAGTGACATGAAGCCGACGTATACAGACTAGCTAGGGGCCTACGCGCATTAGCCGAATGCCCGATGCCTCGCCTGACAGCGGTGCCATTCCGTGGTCTGTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAAATTTACCCACCGTTCAGTAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAACGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGG
+
I0'63:;I(3I2(;<6686I/'9674=47I'56I(6I(28:69I(I(8687:35I(57I;+&68I';9999I0'7I(5;I.'=8I)3:?479676514;H'I0'657:<9:I'79I(5;567476I<+&G'::97744:7&.578I(0I)6;7=<86:8::86:;597:I;+&H'5;:368<9I(87H'8F':8I6)6=22I(86<I(6894489I(57I(8I(F'86I(76=:I,;5I(I(7I9+&I)7I'839;;7H'49I':96I)788I*39;5I(I0'6I(8I0'I/'3I/'7I(7I)27%4G'I9+&64668:;;49I(;D&I'64I(I-&7369887I2(75I(35I(6I0'6I(:1I(I(57<347975:A:7I(687876961I>,'4I(9I(61I)&8I.&876658I(4I';498>8I(=6:7I(I(9I-&;I)I)
@simulated.235
CTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGCACTTCAGACCTTGACCTGCACACCTTGGCCAGAAGGAAATGAAGGTGCAGGGATATGCTATCAATTAGCCTAAATGGATCCAGTACTGCCCGGGTGTATACCTTGTCCTTGCTGTCTGTGGGGCTTGATGGTGGGCATCTCGCACTCACACAAGGTCTACGAGGGCATGGCGGATATTTTGACAGCGTTCATCTGGGTATGACGCACCTAGTAGTGAATAGAGGCTCTCCACAGGGTACCCGGTCGAACATGGGCTAATAACTATGTTAAAATAGGATGGCCAGCATGCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCATACCCATTCCTAT
+
=6583>H'3H'I(8I)68I(365H'9=8I(I'7I(>I(8877=I(836:I(I)64H'776556I)I(I(I(7:I,I'I0'94I+I);:66I-&9@::84'?7;I(I(83I)CI0'5I(48I(;8>:8=1I1(I.&347987I(I)5;I(G'3<88<3577I<,&8I'559I'8I,&34;388:447566<9:I(I)&796978I-&368I(7H';5<I=,'2:<2855F'87<:9I2(477625789G'77>49:93I(9882G'941:I(775I0';7I4)I';7=I(698I0'68I(6I):15/8I)I@-'44I)46H'H'94:48868I(;I(57I7*&03647;62597:I':55I)I(4I(998G'357H'8956I/'976I(6H':44767989<:=5767899;9I(I(>5@8I-&7I,I(669
@simulated.236
GTTGCGGGAACAATCTTTGAGCAGCGCGAGCTGTTACAGCATTTCGTGAGTGCATTCGATGAGCCCTGCACTGTACGGTAGGTTCTGGTAACTCATCCCGTTACGTGAATACAATGAGGTCGACGATCAATTCTCTGGCGGTACGTGGGCAGTTTACATTATACAGATTGTATACGGAAGCTGTTCCTACTAGTATCTTATTAAATAATAGCCAACAAACCGTTGTCGGTTCCGCGCTTGAATGCGCGCGCCTGCGTACGATCATGTGCATGCCCGAATAGCCGACCCGGTTCATGTACGATCCGCAGTTAGTTCACCGCCAGTTAACGGCGGTGACGAGGAACATCTATGCCGCCGACGGGCCCATGAA
+
7I(=2I0'I)5G'99I/'48:;5878666:=38G'76;3:5I.&6688<6=759I)3<57:92I.'<<:5(3688;I(9<I(I(44I)8I(;<:67I0';I'81168I(;98I)<:8I(;878777:6I)I(87:?G'3G'96969I.&=9:I-&9<6E&7:766>8I)8:9D69I(I(;887I(G'5&5889):9;I)6I'I/';I(:67I)F&;I1(I'7I(779I(I)I(8687I(:I,52574466E&9/:7:4<;;;5;8;64>98<I/'@I'518I'5:I-&I(I'9467876613I(7779I(61H'99I)<G'25I'I(:G'6I)979789G'I)>;4<<487H'7I'958I1'I.&6?4F&
@simulated.237
TAACGGTCCTATTTCATTGACATAGATGAGGCTTAACTTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTCGGAGTAACCGCTATAAAACCAACGTTTAGCGTGAATGACATGAAAGACCGGTATGTGAACAGTCTACCTTTCCCGACTAACATCGTGACTATGTGATAAGTATCAAATCAACCCCCACCCAGCATGTAATGGTAAATCTTTAAGAGACCAGACGGGCAAGCCTCTCAGTGCCTAAAGAAGTCGGTTGCCTGGGCCGTCACACCCGACTTTGGTTCATTGCTCGATTAATTGGTATTCGTTGTGATTCCGGCCTGAGATCGGGAGGATGGTGTTATTTTGTCTACGGTCTACCACTTCGATCTAG
+
5I'7E&8I)<9I0'22I(73798883761I(4I(I(6I;+&5I)H'80/:I(78I'I'379I-&583<I9*&7I)<8'I(I'9:328I8*&G'I()1I-&6:5)4AI);738<86I2(7:I(I'678986I(?796:66I)I/'I0'8::8I(86=?588<969213587I'669;3I3(::E&II2*&4I-&9:7;9<6H'9I(=I1(:8I1'I(9.:?I(2;;<I/'9I'4I)7945:88:I(8I2(;I)94<I(H'9H'5I.'H':26899I6*5<8I0'I(I(59I'8;9447I)F'I(I(:6I);4I,5582I(H'I(G'67<6867I.&5I'9BG'3:I)9I>,'764446I(<367I(<7I'&?976352
@simulated.238
TGGGCATGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCACTGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATGAACGCGAGCTCCACGTGTTTTTCACCACCCACCTGGCATCACCCGTCTTATCTGAGTTCAGGACAGTGTCTACTTTATAGGCGGACCCCGTCAGCAGAAACATGCATCGGCAAGCCTTGGGCGGGCGCCCGAGTAGCTTAATGTACCAAGGCTGTCCGTCTGCAAACCCTAGTTCCGAGCAGGACTCAGCGCTGAATAACTACAACTTGGTAAGATGGGATGTCGAGATGACCAACCCATCAAACCTTGCAATTAGCGGTGAT
+
>I/'888I)96;78I1(I/':;I(66I0':I)6>:87886E&84669I(;I(I(:&53675I)7H'498G'H'7<9585676I)517:69I(79I(7595B76>I(5;:67II3+'96G';I.&3I(<I*37659I/'72:H';86993<I(;<E&487897>8%<;I1(5<7I(6I(6I>,'(;;378<5I.&699:5369H'2I'8I)H'I/'4I/'87I1(>:79870I(I)8466H'H'H'98::H'5=:676I-&I.&658I(I(:2888I)797:5699487I(9I(6:87I(5I)F&6G'988I.'96608<3:8:<4E&G'I0'6<9I/'I'G'6AI(I(554I'7;7:
@simulated.239
ATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGAAATAGATACTAAGGACCGACAGAATGATGCAAACGCTTCCGAAACTACTTTCTGGTATCCCCTTATCCATACGTGTTTTACGGCCTTGCCTCAACTAGTGCGCGTTCTGCATGGACTAATGCGACTAAGGGATCCAGCCGAGAATTTGACGTGACACCCGGCCTATCTCGACAGGGTTTGCTAGGCCATTTTTGCGACACACCCGAATCCGTCCTATCCCAAGATGATTTTGTGCGTCCAGATTATAGATCGGGCATTGTCGAAAATTCCTTAAT
+
84I):;5H'346I'37894:889G':66:89642;8I'694859;<8:I.&8G'I'8866I2(93CI*II;/)&;97I'3=8I(98G':9I)4;9;89<;I(==9:::87G'@I.'57I/'7<67;:6I(79:7968I-&80486I2(58:=;77:I(I)6I'88779I(69;9<?I1(733I(I(6I/'995:I-&84I(35;I?-'H'::F'9858795I<+&;7I'I(I(6H'49I(17%635426:I'6;7686G'727I(7=<6536H'I/'87I(55H'667I'I1(95399:2;6I-&I(I)86187=7762I-&I,&77::I'H'7IH0)%695<8385I1(4I(1I(&6H'9:7I/'I*=3279I=,'7<9825I'643H'<9:69:5I/'48I'85;6I>,'I(I(I(I'<
@simulated.240
AACGCACATGCAATCATTCAATTACATTCATCATAATCTCCCGCGAAGACGCATGAGCTTCGGCGAAACTCGTAGTGACCGCGCGCCCTGGCATTAACTACCGTTATCCAACTTACTGATACGAACCGGTTCCTAGGGGCTCGATAGCAGACCTGAACAATACGTGTACTTGGGCCCATTACTTACAGTAATCGATTTAAGCCCTTGCTATGAATCTTTTCCATTGGCTTGTAGCACTGTTCACGTATTAACATCGTCTTAGCGGGATCCGCACGATGTCTCCTAGTTTTAGTCACGAAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTTAAGGGCTGGCCCCGACAACC
+
I'586789<8:I(667H';H'I(7:7I(5;2948H'764I.&783H'7;54478757=I'5H'6%I1(796757:689I)3:;::I/':I'9<H'G'738I(:I(:3I(I(;G'77:397485I(I(I'I*I(58I9+&7412:9888646I'8=I(6G'876<:02;8I(I/'I1'5I(6:I):9988H'95(8I-&I(6I0'I)6:7;65I'65IF/(I):F'I(9G'<7;:;6476I(8;8:83I(I(=7814:;I(?86I/'28I(4;:9795768:I)58:I=,';599866I-&I(4:6F'I(;5I(7:I'8I1(8;666;477I2(I(I.&I0'I)6I(I/'I'I1(<8I'I;+&6;6I'I)
@simulated.241
GTGAAGTTACACTATTTGATGCGGCACCTGTGCCGAAACTTCGTCGTCACCTGATTGCCAACACAAGTACCCTTGACGATCGCTAGGAGTAGGGCGGCTCCAAGTGATCACCGACTAGCGGCAAACGCGACAGTTGACCAGTGCGAAGGCATTACCCACTCAGACGATTGAAGCTACCCCACCGGGAAACGGGATGTGCCAAGGTAGATGTAGAATGTGTCAAAAACTTGTGATAATCGGCGACGGGTGTTAACCGTACTCCGCGATCACGGCCCCCGCACTATATCACGTCACTAAAGCGAACGCATTCTCGATGGCGTAATAGAGGCCACCTACGTCCTTCAATGCGCACACATCCCGGTGCTGGACATTTA
+
487I(4I(255767I0'<:::7I(84H'9489I(5I2(4I(?658:387I(765I(2I)I(842I+875I1(H'78=75869.66H'495:I/'9H':5I'H';986877I)348;967H'3I.&6778=148I(:9E&<:4>>8H'I):3I(8I.&476;70;<75I'7H'3485I>,'3I)I-&I1(<I1'5<687I)I(I)43;677888I)656998IG0)%6I(85>:4I'66G'6:66I1(:7I(I(H'%;838I)83688984I'IH0)&5<;65199:96=9969;:I-&589I(7;37I(9:5;59I(39<I'877:H'I(5I(8D786I)I(8H'382978;;786I,&I(4>99I';83I1(6
@simulated.242
GTCACCGCCGTTAACTGGCGGTGAACTACTGCGGATCGTACATGAACCGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCATTTCAAGCGCGGAACCGACAACGGTTTGTTGGCTATTATTTAATAAGATCTAGAGGAACAGCTTCCGTAATACAATCTGTATAATGTAAACTGCCCACGTACCGCCAGAGAATTGATCGTCGACCTCATTGTATTCACGTAACGGGATGAGTTACCAGAACCTACCGTACATGCAGGGCTCATCGAATGCACTCACGAAATGCTGTAACAGCTCGCGCTGCTCAAAGATTGTTCCCGCAACTGGCCAACAGCCCCTTTCAGTTGTCAAATCAACATCCGCGTCGAGGCTAGGTACGGTCGCGGCATTCACCCGTCGGAACTAAACGC
+
6479I(9I)6I'I)82I';I'67I'46D5<?6G'4:658:2645I(I'I,:7I)76:H'8I0':7=8<457:77/::74959:I(76>;5898I0'7I)86<9H'I(I'64:I'8I'I3(:G'I(<98I(1I.&I)6I(>8767834I)I(:<85I(G'2:I(547I'6:574<4I'878I0'478I-&62886I'7I(6674I(I)899:766:7I(518I)7<7E&49286H'7I/'97997I)7I';6I)I(88H'3<<68=87;I1'64;99@<I(5158;88558I.'658:38G'6699<6;85<7:7::I/'67I(7I*I.&89I(44F'H'I)5:9I>,'I.'953I(5;7I/':3I(<78I(4986779I(886I(726I)<758I)7;I(7<I.&:65I(H':;I-&554
@simulated.243
TAGGCTGGGCATTAGCTGCGTACATCGGTTTGCACTGTGGCTGGATGTCTATAAAACCATGCTAGTGCATGAAGCCGACGTATACAGACTAGCTAGGGCCTACGCGCATTAGCCGAATGCCCCGATGCCTCGCCTGACAGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCAAATTTACCCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTC
+
25I)56I/'99I)6<<986;;7189>F'I2(5686878G'89I(54:97<97I;+&I(:69999575;;44I(3I+:95=:456874>7::6;;3I7*I(7<73887<D&56I'8I)96I=,'869;I';47I)86894=.I(99I'5H'I)6@F'?<63I.&4;I(F&8I9*&I(5I(68:376I(86I(17:I'673I(8788I)I0'8I(:I.'I0'9I0'8E&8I(:26I(I;+&968:38894:I'7H'I'74I(I3(964:75<I2(=6I(33I'3I.'5I(94I'G'678<;9647;598I)85:;8664>I9+&?H'9I(87E&3I.'868623I'5I'6543:3I):978F'I)4I0'8H'I(I0'957=5I':;8805I-&<9:749I(G'9I'I(5:>44
@simulated.244
TTCTCTAGTCTGCTGACTACCAGTATTGCGACGTTTCTGGCATGTTCGAGGCAGAATCTTCCCCAGACTTAGATTAGGTTACCGCCGCTTTCAAACTCATTTGTAGTGCCGGCTAAGCAGCCGTATCAACGTAATCGCATAAAAAGGCAGGCATCTAATTATATTGCATGGCATGTGTGTCGCTTCCTACCTTCGGTCACTGCTCACCAGACGGATATAGTAGTATTATGTATAACGCCGGACTAACGCATGAGCGTCGTTCGTTGCCGACTTGAAATGTTCCCGAGGTGATCCATATGCTCCCTTAAAATCGGGTATAAAATAATTCCTTACGCGAGCTCCTGCATTGAATCCGAACGGGTATTGGCAGCTCTTACGTAGTCTTTGCCGGATTTCTGAGTGAAAAGAAAGCCCCCCTATGATAGAC
+
F'6777658279:19::88I)6>:5I(89:773I-&87I):1><E&64;I(963H'51I(I?-';9&=I(6:9I(6H'H'9I*7I(:7I.&:I/'5354I.&657+=8I)I)6%G'5:>:I'7;267I*586G';8:8=8II0)&I(;8I(;7:67I'H'29=H'6826I)35D9148477;5G'E&:7I(I(6H'9787::6<85E&2:97G'8396965765:I)869885I*97E&I(=64I'96639>7=9:6=<I(6<I(7I()68I(6I1(37E&I/':;I+887:H'<8<8688I2(I(I?-'75I0'46CI<,&8I*I'I'I(7497/:<::I)7<98I(4I)5I(3G'7I0'75I'I(:99<<;D&:/?7-7<7I.&:I)I':I1(:967949I=,'2I.'6II;/)&9985959831
@simulated.245
TACGTAAGTTGCAGGTCCGTGAAACTTGCCGCAATAGTGGTTGTCGGGGCCAGCCCTTAAAGGATTGGGCCCAAGGGCTGCTACTGCCCAGGACAAGCAAGGCGTGGTTTCGTGACTAAAACTAGGAGACATCGTGCGGATCCCGCTAAGACGATGTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCAAGGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCCTAGGAACCGGTTCGTATCAGTAAGTTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGCGTCTTCGCGGGAGATTATGATGAATGTAATTGAATGA
+
:=7@5H'8I'7;:I(7E&;8?I0'4G'7I(75I);77BI)E&=73I>,'I(56I.'I*I0'I'8H'I3(I.&I(I0'7;5986786I.&8I(66I(7=H'H'784I'I/'957<>78I8*&95=I*2<9:86387:7I(?7I0'706I(5<=8><<I(I'89935:I(57;6:<=76I)7I)I'7I'IG0)%6:I);857=5I(I.'7H'I/'85;I(88687G'?4I*8I-&I-&I(9.:759:67I(7I(05I'5:145:7:5431I7*&78I(I'H'I(I*4@53398<6F&<I'H'=9H'5I(539I(G'49I)7I3(58856I(544:747686I2(6I)6I'7<87:<36=45H'687I/'875H':65869I(546I(I)7G'7:7
@simulated.246
CCAGTACTGCCCGGGTGTATACCTTGTCCTTGCTGTCTGTGGGCTTGATGGTGGGCATCTCGCACTCACACAAGGCTACGAGGGCATGGCGGATATTTTGACAGACGTTCATCTGGGTATGACGCACCTAGTAGTGAATACGAGGCTCGTCCACAGGGTACCGGTCGAACATGGCTAATAACTATGTTAAAATAGGATAGGCCAGCATGCTCCATTCATTTTCTCATATATGACTTGACTTCCGAATGCTTGTGTTGATGCCCACGCCAGGAGACTACACGCGCACACTAGCGGTTCAGTACCCATTTCCTATGATCTCTAACGTTGCGCAAGTTGACGGGAAACGGAACATTCTAAAGGTCCCATCCGATAGGATACCAGAG
+
I);488<82I0'I3(9:6;09I'I'79I(I(><37759:9I6*7I*49;F':I3)4:3;52;846:58455I'I(565747I/'99<I(6I);66I7*&945=6%3=I(64866I0';=49848>9I)6D<3;946I'65(8;I'896&5I(348I.'86I,I(77<I)86?I,3;E&8G'66598H'I8*&77I'::%F&I'38874<79I'3I(87I8*&5476;64:35<;G'868I'G'9I)967H'996I'6;:9I3(716G':I*6:47340958572;9487;67I)I(:9&:5I.&6I2(H'36:8879897I)95I)58<4I';G':55I0'I/'8I(G'27I'43I0'I(7I/'8:I(877;H'2<&F'8749
@simulated.247
TGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCCTAGTAAGGATTTGCACAGACTCAATCTAGTCACGTCCGCTAGCATCGGAGAGGCGACCATAAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCCGTGACTACCCCAGATCGTGAGTATACACAAAGTAGAGCGAGCAAGCTACACATGATCTACCATGTCGTCACTTCAAGGCAGGTGTCCGCCTGGCCCTTCTCAGACCTTCTCTGTTCATAAAACTTACGCATGATGCACCCCGGATAGCCCTTCAGGGTAGGTGTCTAGATATGTCGAGCGACCGACGACTTATAGTCAGCTACGGTCCCTCAAT
+
9:98I/'65I2(:I'82056677I(856886:7I(47I(;6I(37;I(89:II;/)&I(955I.&84<;H'H'9I-&88537937=:H'<4:7835:968H'8944582;9I)668I+659I(85I-&5I)09I)838<<<1<534I';886I(=8I(258;;I'I(8278I(I(:I0'I1(I(5936I0'<7474<8I<,&::7976885;:633;9:I/'87:76999796I(6<;76896617964;I'64<:3;97?6I':I)I(6;I(5;6I(6I(8I'I-&I(;57>4=I(I):757:I(438I:+&6I)86:6:57:/684I8*&H':;6:I2(I(58I/':6I(/=7788:77584&9619693I(98:8;7I'46<:::785795I)9I0'27I)7
@simulated.248
TCCATAACCGTGTGGGCTGTGTTACATGGGAATCCTAGCCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGACACGGACATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATCGAGCCCGTTGCTAGTTCCTCGTGGAAACGGGATCGCTAGTGGGTGGATCTTCTTATTCACGAGTTATACACTACGTACACCACGGACTAGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACT
+
8I(43I)D&6748I0'77:88E&;97;I1(I(5I)869I);5I(I0'H':675I=,':;86844947<I(3215;38849687I(9961I'D46I);;0I(I(I(:89798H'I(:699789:69I)86=785IA-'6=7I)8I)8;I(I/'I(67=I'87I.&770759766I0'I(7H'5I*746336%;65I3(6G'97479F'G'5'8;I(I-&9I1(6:7:85:%4I/'7I'442I'7I'5I'83'583I(3:948784;&566@G'46I'4@:&85975;I(55;I(95I)9I(5I'98I/';7688296I)I(:;8F&=I>,':6866:60>I)I)5I/'I(<378
@simulated.249
ACCGTGTGGGCTGTGTACATGGGAATCCTAGCCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGACACGGAACTATTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGG
+
7I(6289I/'789:6D4818I/'I)7I(79;I':3H'I.'H'6837I>,'8;795:67697I(554;9:84:6688I(96=5I(I)2%6F'95=H'I(I(:<<618I'I'7776467624I'758<69I<,&8:<E&8E&82I'I.&I)736I(6<I-&5897:469:I.'I'<F&3I'8956;:48:I4)9I):7984I(I)654I(I4)8I.&5867<2;4I2(=I+5=:I(9I'5I(398;9I):4964654:8>63I(77H'213854794I(5?9F':8I(7I':I(83I-&655836:2I'I(;59I(4I=,'937:87869F&I(7I.&I(56:0674I';I'5;8I.'I,71I.&;9<I)784677723F&<97::::I2(I(89II1)&9097I/'59I)=6239E&4:77I(I(I(
@simulated.250
GTTAATACGTGAACAGTGCTACAAGCCAATGGAAAAAGATTCATAGCAAGGCTTAAATGATTACTGTAAGTAATGGGCCCAAGTACACGTATTGTTCAGGTCTGCTATCGAGCCCTAGGAACCGGTTCGTATCAGTAAGTGGATAACGGTAGTTAATGCCAGGGCGCGCGGTCACTACGAGTTTGCCGAAGCTCATGCGTCTTCGCGGGAGATTATGATGAATGTATTGAATGATTGCATGTGCGTTGCACAACCACTACAAAGGAAGCCTCGAGACTTCATGGGCCCGTCGGCGGCATAGATGTTCCTCGTCACCGCCGTTAACTGGCGGTGAACTAACTGCGGATCGTACATGAACCGGGTCGGCTATTCGGGCATGCACATGATCGTACGCAGGCGCGCGCACTTTCAAGCGCGGA
+
3I'I(979:3:I(59898688<H'9I)G'5I(II3+'75I(672433I)I,<I(I/'744G'>6>:6H'79I(7I1(I7*I)955:3=4;=I(7H'<:I(873487746<<;I7*?>H'I)H'I*I(68769<::5I'6DG':9G'8I(959I(I(88I(9I.&16673H'97;;<58;98I-&?I'9I'479=;899656H'427I/':8;I)6785=5I)7;4DI(9I'8<9I)6889974;5I(;6:8I(I(7;:67I3(I'I)6I)775<58,I(556I1(I/'86;I'8H'64:<;;79I)I)9979;7I)3I(6I)I(9@I(8I(65I*98H'3545I*5998078677H'I(I.&88I(668I)3I.&<;<724::6:955876=928H'::;68;:6(I/'6I'4935H'<
@simulated.251
TGGTCAACTGTCGCGTTTGCCGCTAGTCGGTGATCACTTGGAGCCGCCCTACTCCTAGCGATCGTCAAGGGTACTTTGTGTTGGCAATCAGGTGACGACGAAGTTTCGGCACAGGTGCCGCATCAAATAGTGTAACTTCACATGGGTTCTCAACGCGATAAGCGCTTCGTATCCTATCTTTCGCTCCGCTTATCCCCCAAACCTCCTCATGGAGCTAAGCTAGAGACCCCCTGCGCCTATCTTCGCAAAATCCGTGTTCTAAGGCGTTAAAGCAAACGATTTAAGCCAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACTAGAACGGGTTCCAGAGTTGC
+
8I(:4F&56666<:5I.'2I)2;893=3I(78:78:1I(I(77I(8I.'59:<I(375637:88=<I*I2(;38I/'263I(I(4I*217I'6<:;82:7I(:I/':I'8554H'48I(3;466I0'589537I'6I(957<7I/'I'863I(<46745I,9<4CF'94;;9I(88;9I0'2@68I(46I(;:II1*&I5)I'9I(79:4I(:7;4I(75646775II2*&86<7I*8976I)859I;+&2I'656I(A6I(I(>6I)I/'99I/'97>I.'I(6H'IH0)&56561I'8I'I(58I*77I(=6I(86689I-&36I(1987:=7>=88G'4I/';7:I)=I9*&52<7?E&9:I(I(9=I(I(7;48;22I)8<9H'I'4549;5<<<78:I(2H':47:I(:'49I(4I/'I(I(::99I(?4
@simulated.252
GAAACGGGATGTGCCAAGGTAGATGTAGAATGTGTCAAAAACTTGTGATAATCGGCGACGGTGTTAACCTACTCCGCGATCACGGCCCCCGCACTATATCACGTCACTAAAGCGAACGCATTCTCGATGGCGTAATAGAGGCCACCTAACGTCCTTCAATGCGCACACATCCCGGTGCTGGACATTTAAAGGAGCGCTAGTCCCCGCGGGTGCCAAGTTATGCTTGTAAACCACTCGACGACGAGTAGGTTGGCCCGTTTAACTCGACTCTCTCTGGTGGAGCCCGACCTCAGCTAACGAGCCTTGGGATGTTCGCGCCAGTAACCGCCAATTGGACCTGTCTGTTATTCACAGTCAAGTTGGGAATCCCTGTGGTACGCT
+
8I/'7I-&7257<I(I'I(98;;5765;I);5@846II3+&4G'A76<9I':<I)7445I,<8H'I(G':4@:I)9=8;3588I'IH0)&95786:678<778>9<:5I0'057I(3647I(<585:5G'788I(<356I)I(:I(8I(2:8E&G'7I(97454274667I2(I(7759I(9:4I0'I0'I(674454874I=,'87I/'8:I(I(:H'9/7:I(76I-&H'893;888646=;877I(F&H'I/'4I/'I(5?:76<:;76866I(7H'66I1'97I(<98979F'4;:6F'I(I.'577I(:676I)6:9I'I,8I*I(I)I(?H';5975<H'9I)734258=I)5H'I1'I(7I0':78I(4;7=7<
@simulated.253
CATGCCGCTGTTTTTCGGGGTCACCATGTTTCCTACGCTACAGACGAAGCCCCTTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACACGGAGCCATGAAAACGTTCGAATTAACAGCCGACCGTAGTATAGTAGCGGTCATAATATTGGAGCGTATGAGTCATTAGCGTTCACACT
+
85?7G'569;II2*&CI7*&547I(885I0'I(56'5<79366477I(9I@-'I.&;881776I(6362I)86I/'>86I/'<976867:5;799484;<3I'658I)536I)=9I(9I/'956765I'560A96847668:;I.'658I(4684398I1(999:79I/'55667I-&6G'98I=,'5I(I0':66789I(:886;6:6978:8374I(:>6=626I'713:I.&975:;>H'I)I.&I(78F&:388IB.(I)49H'I(I)<5;6579E&9;4I1'8F&I0'E&66I(7;636:6I*8:7=9:6;<E&I/'G'6;65I4)=;6G'7:F'977I<+&47I(;4I(I(I(<=;E&:9I'58%7C956=4663I)9::9G'74F'I(=88>:394<6:82I*&898H'947688
@simulated.254
AGGGGTTGTCCCGTGGAAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTTATGACAGGACAGCGTGAAGCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACTACTGCATAGGCACATCCCTACTGGTCGGATGGACGATAAGCCGGAGCGCTTGCACCTAGAAGAGTGATTTTTACTTTTATATCGATGCGCATTCTAGTTTCAAAAGTTAGGGGACATAGCACCAAAGGACTTCGCTCGCCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAA
+
6I:+&I(53I/';7I(I,&<9765=9:5I/'I)4I(65=74G'67>I/'9I*I(I(7;432H'7>6;5;535688:H'2I(673G'I(I(-I)6I1(:I.&86:974I)77=;2488I)6I'<637<74I(5H':744I(68I/'76?:I(76>8I(784;G'5I;+&:49;5G'8:::97%66:86577I(:6447I0'6;;=I(96I)96I(::376I(5I)H'4594:I*:2:I(888G'6=57;1II1)&79ID/(578;9:0@8;?;7I(8>75I.'<I<+&5I(7I;+&:415:893I+I/'I(87I'8/6593I=,'9G'I(;9H'9443386F'I0'867E&73I6)I.'4I/'80I9+&<I)<82;5B973535I(<H'9:555<<738I(<29F'99868:5989889I)87;9I(7;;894I(<;6;6543:5H'=7I/'8I(5>I<,&
@simulated.255
CTGCGGAAGCTAACGCTCGTATCGGATGATTAACCACAAACACCTTTGGGTTGCCTACCCGCAGATGTATTTCTAAATTGAAACTCCAGCTAGATTGAACGAGTTTATGGTTGCGCCAGTGCTAGATCGTACGTCTCTCCCGGTGACAACATGGAAATTCGGAGTGTGTCGAGAACTTCAATCAGCTGAATGGTCACGAGAAAAAATGATCGTGTCCGGTAATGTATGCGAGACTTTCATGCCTATATTGCTTTATCCAAATGCACTGAGTAATTGACTGCGTCGCGCGGGTAAGTAATGACTTAGACAGAGGTCCTGCCTGACGAGTAAACCCCGCCACACTAGCTCGGACTTTAAAACAGCTGCCCAAGTTCCGGTGAGAC
+
6<93I)I(8:3I(7835;95D6<I'8957I'I)I(7:I.&:9I(I0'I0'I(<H'9;I-&7797:4974I0'44I/'I(9I.'65I(2<96;:8I'<I(7744I/'6:I(I(948I(9788;96865:9:899699:2I2(I(=:9:F'2?9F'I0'G'=I(:44:99&8478I)5I(AI(5:4639;I)?I):8148<7II:.)&393:7:42'I)I(:I(8878:A398;68I.':69<I(8952I(82I.'96I(I1(2<75*99946I'I)376<98:79<6:8I1(;H'47I(:965I(7<3::69I(>H'66H'9546&;<9I1(I>,':I)8454(36787F'55I/'I:+&74::6;I0'I(:I(I'I'9:7653
@simulated.256
TTTTTGCGTACACACCGAATCCTCCTATCCCAAGATGATTTTGTGCGTCCAGATTATAGATCGGGCATTGTCGAAAATTCCTTAATAAGCGATTGCCAGAAGTGTATGGCACTCCCGCTGTTAGCCGGGCCGGTGCCGGCTACCCCCCAAGCTACGAAGTCAAGGCATCCACGCATGAGCCGCCTTGATTCCGTGGACCTACTGGATCATACCGACCCTTAGAGCTGGGTAGGTTCGCTACGAAATCACTTACGATATGCCTGTCTGGGGCCATCTCTAACGTCGGCGATGTTCCCATTCAGCGGCAAGCTCTCGTTCTGCATGGGTCAACTCCCTCACGAAGAAATAAAGTCTGTAAGCGC
+
II3+'5:3%6;867I,<E&;H'9H'6<9I/'I(92=97I<,&939385I(7;6I(78;76:5I0'7:I(7896I<,'I(G'I(E&6I)5429I(9I(75I*376695H';7<=I0'>9:;F'8?I(I/'I)I(8:F&I'85<II=0*'I)5<973CH'974I'I(9D6I(:45498425I(4I(H'48I'I)64I'8I'8:34I(7964;8I(77I/'I(249875I1(79I(I(4709660I4)73?9I(:>778;67I(66956I=,'I)<73593I(835:I'76974I(I1(5F&<657I(6H'4262058H'6898<8I0';:I)39I.'68;68I'5I-&8I0'912968I);41;
@simulated.257
CCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCAGTTCTTTTTAATAGCGGGGTGCCAACCTTCCCTGAAACGTGGATTAATCGGGCCTCTGGTACCGTCAGTTCTCAATAGCGACAGAACACTGAGTCTGGGGGCCCAGCGATGTGGGCGCTTGCGCTATACGATAATTGGAAGACATACGTCAAGGGGTTGTCCCGTGGAAAGCACAGATCAAATTGAAGACATAAGATCCCTAACCAAGTAGCGGTATCAGCTCTACGAACAATCTAAGGTTAGGCTTTATTTATGACAGGACAGCGTGAAGCCAGCGACTGGCTTATCGTTCTGGGTATGCCGTCACCATAGCCGAAAAGTATAGGTAGCACACTGCTATAGGCACATCCCTACTGGTCGGATGGACGATAAGC
+
I'7I*H':4785I(998I:+&I(8I)<<6H'I;+&:27I.':9I);II3*&D&8:47I?-';6H'G'H'I*I/'0<I.&659H'4F'I)86I-&I)557G':2I(68958H'496G'89169;2:9I(476581(94:II0)&I.&72348;74I/'8:4I(435365:=:;64I(I(I)I(64;6693::8I(I<,'I';9I-&97G'I3(456<877;9I2(I'9I(49849I)873I.'4I(I'G'87795H'78:8;875;;859F'7I):98H'I(H'8H'4I3(9I/'853894I(6795774<H'5I(667846=F'6H'?855I)77I/'<<55I(:<58I)8489I(6I7*&76:;8I(7178=866458&9:=I*;37:4I/'9855I)98I(89I(8:893H'46
@simulated.258
TGGAGTAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGACGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATGCAAGGTTTGATGGGTTAGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATTCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGATGCCAGGTGGGTGGT
+
5G'816I(61I(9=I-&8II9.)&8I?-'I(::4:54:9I'A9=I,88H'839I)=4878I(=7I)7:>3I'9:58=9897I(;7:<?H'768H'57I*H'7I/'4H';;5668II?1+'544689;;3;H'9<<0I/'77:I(5I'8786I(4679I<,';E&I,&686F&;=7I(D83I)I(I-&987I.'I''I(2<9:9:867>45I.'998I(5I(I(4I(8987I'9I(74;97537761H'86874I(I(4<7I/'I/'45678:I'783;I'F'I)4::8I(I(788;669I1(9@I/'7I.&I(I':I(8I)6;;4576=I/'8:93?64I=,'7I(5F';;?I0'7755=95578I'5;I(:4=887:I'62;I0'48:98F&5I(7I0'@I(7
@simulated.259
GGAAATCGCCGTCTGCAGAGCGGCGGCGTCCCGCTTCTTATGGCGCGACCGGGCCAATTATCTGCATACTTCAGGAGAGTGGACATCACCTTGAATATAGCCACGGCCCAGCGCTATGTTAGGCTCAGCGTCCATAACCGTGTGGGCTGTGTTACTATGGGAATCCTAGACCTCTTGGGTTACACTTTTCGAGACTCACATTAGACATACGAGTCGGACACGGAACATCTAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCGTTATTGAGGCCCGGAGTAAGACCCGCGATCGTGAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAAACGGGATCGCTATGGGTGGATCTTCTTATTCAGAG
+
I(I-&86;I(6674257;685F'9I'947I1(69I(4H'46G'647:=I*I-&I(I'E&5995=79759G'51D&69456I(96;;71I)I(7I'84=;8I)<8I(I0'614886D89I(3I*76<43546I(77H'F&7:=4I/'9767:I(59%:7I/'I(3I(964&H'65I'I-&I(:835I9*&979:767999:I(229296/9554;7I)4896I)I'8<C8(8<H'I(I(78;554I(I)6876=9713:I'684533I8*&9;3%I(9G'49I(I2(I(997I(38I0'9499488>4I,I(7I);I'6483:36>=I1';I)951<9I)G'<56I)I1(<I-&76677::1I2(8I(938I(2I(:I'7797;
@simulated.260
GGGCCCTTCTTTAGTTCTCGCTAATACGATATTATCCCATTCAGTATGTATTCAATCTAGGTTAGCAGATGCCTAGCAGGGTCTTGACGGTAATAATGCGTGGTTCAAAGGACTTACGGGGAACGTGCACGACTCACCACAAAAATTTACCGTCACAGGTGCGAACTCATAATCCACACGCTCTGGATCCTATCGGATGGGACCTTTAGAATGTTCCGTTTCCCGTCAACTTGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTCTCCTGGCGTGGGCATCAACACAAGCATTCGGAAGTCAAGTCATATATGAGAAAATGAATGGAGCATGCTGGCCATCCTATTTTAA
+
I0'I/'I';I-&:5I,737789F'=78753;I)56I1'6I)465799>:3I(5I(55:8I(I'77326:77I(7923;I/'78G':53I(9G':I)57497I(I)3I/'G'9=H'<4I:+&I(44469;5:647:6I(93II3+&I1(3I'65;676I(=489I(55;94F&9I(454989985I(62H'7316I(94I.'6I(I-&4;I)63I'H'6I/'I0'787I):H'87:4I';<I)8776788465I)I1'7I-&4848I*I)24;5<=87422856>985977I)8H'=67I1'8:35I*658I)870I(6I(I'85;H'<745575;;9;4I<+&86I(9I(7<1<6913I)G'85G'32I>,'I(
@simulated.261
TCGCCCCGCCGGAGTTCTGATGCTTAAATCTAAGACCCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTATGCTACTGCTGTCCAGTACCTAGCTACTAGACGATGCAAACAACCGAATGTAGCCAAGATTCCAAGGCAATGTATCACGCGATTCACTGGCTGTCGGCTGCTCGTTGTATTCATTAGGGTAAGTCATACAACTAATATTCACTTAAATTGACTAACCGGGCCACAGAAGGGTTAGCCCCCGTGAGCACAGACAACTCAGAT
+
;:;I<+&9G'G'9:I':56;598I)I/'739I(63I;+&I0'9I0';9I:+&4I(5558:4693:<5I(6I(846<66::57I(7:3I)658<7=9:65:72I'6434I(36:385I)7876;=;266I(98I.'4G'8;II1)&:798337765H'775565>F&>9I(99?8<82I)I/'<78<4999H':::IH0)&7I)8I(754984(7=9567I(9D;8I)845?6=76;63644::7I.&7I(I(8I':8689I(H'7=G'I(H'I)9I(597:2;64;9;6I(7698I(37645H'9:5>569I);77I)57I)7I.&7I'72;9<:8I):8I)85I(965I,I.&I)8876I(I(I/'I)9322I(I-&I)95II3+&;9597486:155I(563616:
@simulated.262
TCATGATGTGGAAATGGGGGGACCCTCAACATTACTCCATGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGGCAACTCTGGAACCCGTTCTGTTCGTCTTGCCATGATACGACGTCTCCATATTGCAGACATTGGATGGCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTGAATGAAGGAGGTGATCTTTTTGGCTTAAATCGTTTGCTTTAACGCCTTAGAACACGGATTTTGCGAAGATACGGCGCAGGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGATAAGCGGAGCGAAAGATAGGATACGAAGGCGCTTTATCGCGTTGAGAACCCATGTGAAGTTACACTATT
+
:85788799G'I7*8II9.)&2I/':3I(88H'87:I'82778;5I.&8I.'654:3::I(54;4I)::288I(81992I*;I(:<75E&I)I.'<I(786I*38-5I(4I'6459789427:'7DI)698H'8;<@859I(I'85H'D64F&68:73I@-'0I(;:9I/'6I';564;6=39;4G'49I1(7:814I(77F'47I(<9H'I(:I(876=8II1*&I)5G'I/';3;I.&8=I3(I(:1I'H'53H':77I':I>,'5:6I(:743&I(5;34II1*&;74<B8:9E&9794I)3>74F'8I(I/'II1*&76I*:6I(5:74I0'7681I(9767;I'I(89;I.&8=67<:I(;:5I)I/'2:9@;I(:I(67693:F&
@simulated.263
GGGAAAGATCAGGTGTACCTGGAGTAGAAAAATAGGATCTCAAGCACTATGATCAGGTGATATTTGCTAATACCAATGTCGCCCCTCCATGAAGCCGCGCACCAGCTCCCTACAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGGGACCTCAATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCCTTCATTTTTTGTAGCCCCATCACCAGCGCAGTACTATCGTTGTAAAGATCTTGCACGTAGACTACTGGCCTAGCCCTAATCTACGCAACACAGACGGTACGAAGCCTTTTCTTTAAGATTAACGTCAAAAGTCTTCTACCCACGGGTGGTCGCGTGAGGCTTGTCTATCTGAGGTTGTC
+
I.&I0'4;659I(4645I)7I+857<:II2*&79I'98645G'967691574:58G'7<49>I3(:43G';CI+H';=998I:+&8G'5:7I'6I*6566;I(<697I/'756E&8I.'7:4I):I(5378<67;7465I(8I.&I'457I-&I);7H'0;E&I(I(I=,'5I(57I(I-&I)4988I(357576I'68H'45:;7I+:77I0'G'66II=0*&5834I8*&<394E&<78459>7;8<417=I(94I4)5<6;I)3:651898:8964:I)I*<84I0'7I(7678<36I'74854<4I'3638H'8G'I:+&9I/'I(56I(I)6<8<I;+&479I(<84I1(57I4)6I)694:::<1G':G'35>:99@948D&I(6:7
@simulated.264
AGTCGTGCACGTTCCCCGTAAGTCCTTTGAACCACGCATTATTACCGTCAAGACCTGCTAGGCATACTGCTAACCTAGATTGATACATACTGAATGGGATAATATCGTATTAGCGAGAAACTAAAGAAGGGCCCGCAGGATATCATTCCATTACTTGATGGTAGGCTTGCCGGTAGGGTTAAGACGCCCACGGTGTAACGCGTATTACCCACCGGTGTATGTGCTCTCCTATATGGTAGCGACCGCGCGGAGGAAAAGCCGGACTCCTTGGAAGCGAAGTTGCACCCATACCAGCCTCACGGCCTGATGAATTCAGAAAAAGCCCAGCGTTTAGGGGTGCCAGATCTTAGTGTCCGGCGGATATGCGAGAGTATTGGTACATCAGACTGCAAAGGA
+
783:9;.6:<8I(I<,&89I*97I(I0'2H'I)68855I(7G'6I(:68I'::I,91797E&<58*;5:68I(I)9775I(>D:9:3=3758I)6I/'57G'6::4<98I*;21415I6)98I/'7I'I.'I3(375I(4296<8I'H'7H'34H'778I':8H'4I(8G'I*<:I-&I(I(9;17I3(6;I(3:7I(69467:H'8I1'6I*G'98978888:;47I(:<4=8H';7:699I(96;8I(5E&I;+&8G'I(8:6I(I*I*G'789I)7I(397I7*476G'5:G'A847H'H'7749=I'I)356IG0)%6I0'595,I.'4I:+&37H'67367I)55;6@I(I(7H'559<78966<86:I(I*7<65543657257I2(I)3
@simulated.265
GTCTAATGTGAGTCTCGAAAAGTGTAACCCAAGAGGCTAGGATTCCCATGTAACACAGCCCACACGGTTATGGACGCTGAGCCTAACATTAGCGCTGGGCCGTGGCTATATTCAAGGTGATGTCCACTCTCCTGAAGTATGCAGATAATTGGCCCGGTCGCGCCATAAGAAGCGGGACGCCGCCGCTCTGCAGACGGCGATTTCCACGACCGTGTTAATCTTTGTCGGTCACGACGGCTGCCATCTCACGCGCGCACGTCTCCGTCCACGAAGTATGCATCATTGTCGCCAACTCCGCGCACCTATTGCTGAGGACGAGGTGCGTAACCGCAGTCTTCCAAATATCCCGTGGTCAATAGTATGCAGCTGTGGTACATTCTGGTGGCTGGATTTGTACTT
+
8;56F'8;3765=77</I8*&7879I(I0'I(85G'844I)3I'I/'787:I*51682I/'87@5I(I)75F'42986575I(8I'68I'879<>7I/'I(67I'=:5:6I'6H'E&99/=75H'76;;7I(68I(85:674:856I)I'I(I.'I(<648:I'59I):I(65I/':81I(4G':66<==8:193I)599I3(I':466I'9;<I(I':8I/'=6=I(6:46599I(9;:I*398:63585;8456365>4I(::G'5;8I'999589::7<H'6>:<I(I(85I'86:58I)73I*5<:37I(9*:9I(86787I(H'94577BI(H'I0'947I/':5I(@:I(488330:09;627;I(9;87I)7;I);I'99I(7I0'9397E&
@simulated.266
ATGGATGGCAGTGTAGGAGCGACTAGATTTTTGTGGCAAATCTTATCTGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGGTGTTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGCGAAGTCCTTTGGTGCTATGTCCCCTAACTTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGCGCTCCGGCTTATCGTCCATCCGACCAGTAGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCCAGAACGATAAG
+
28F'?5I(;7;5786F'326:56257<II4+'78F&6I.&54H'586A2:7786I(237957I(9997I(:49765;;86;99I':19I)6<4579>486I(4I(853391769656I(1I;+&39I.&;I.&I;+&58G'9<4I-&I(;567:54I)5;I(H'9I>,'>68729F';6I(I0'I*32255231I:+&<I(9I<,'9I-&>7:8I(7;7956;48<968I8*&;6II1)&944376G':97I'646I(46734I(H'8D&98748I'68I'7;I*<857I+:5348I*8;;8779=388:;:I(14:77I@-'7H':422I(6:;2G'@36;I0'78I)389;I)9
@simulated.267
CGGCAATTTACCACCGTTCATAACCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCGACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTACTGCTCGTCGTACCAAATCGTGCCCGCGTTTTTCCTTATGGAAGATAGTGCCCACATGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGGCAACAACACTAAGTGTAACGGAGGTGGTACATAACGTCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCAT
+
:I(:I,I.&7I,7I(3I'836I)I7*7:5:9689:7I(6I(I(7=G'I1'7398466I,&84I(78H'9I2(4I(;2I(I(8876;:7568:5;H'757:6:47>I9*&;G'4I(6;I(8I/'68779<I)2I'9689=6I)478<I'I'5I/'6H'E&I0'9:%97:H'28:<18I/'3;8388I)I(7I'E&9586%9<;:<:98766:H'I4)7826:I/'037IH0)&I'H'89I(I)5<<6856I0'887757955I*96837>/99I4)F'86<85?976I);;:6947438I/';8<88=9I.&9I(84?6I'E&I'7;I=,'894I(I=,'5I,3D&9637I*::55I)5I(6I'9I*:0=58I'(3&5590I(597611:5F'I)I.&G'8I(=8I(I(:A346975G'9598576;78<66;9I(77
@simulated.268
CCGGAGTTCTGACTGCTTAAATACTAAGACCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTATGCTATGCTGTCCAGGTACCTAGCTACTAGACGATGCAAACAACCGAATGTAGCCAAGATTCCAAGGCAATGTATCACGCGATTCACTGGCTGTCGGCTGCTCGTTGTATTCTATTAGGGTAAGTCATACAACTAATATTCACTTTAAATTGA
+
I(F&64I(:<18&778I(I2(<)68I)66I6*I/'9I/'36IA.(3I(4455>7466=26I(7I(95787857<>I(9:8I(7667<48569168H'<24=I(5:<0=7I'8;853935A4G'75I1'8I(6<II1*&4897886979I(:7::9;7F&8<G'8<354::I'I1(32:-87;6I'8::II1*&:I(.I'998<7.539<99H';I(6:F'66646445C7<856926I-&8I(I(7E&696;8I(I*17H'I)H'I)4H'46958@89>:99I(9358G'42:;3I(87:72:8I'896I(8'5I':I.'7I(7475873I)66I'54I(645I0'I0'I';;
@simulated.269
TATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTCCGCGTGATTGTCCATGAAACACTCGGGCACACATTGATCGACACTACCGGGTGGAGCCTCCCTTCGCGCGCACTGTTCCACCACTATTCGCTATCAGTTCGTACTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGCACTTCAGACCTTCGACCTGCACACCTTGGCCAGAAAGGAAATGAAGGTGCAGGGATATGCATCAATTAGCCTTAAATGGATCCAGTACTGCCGGGTGTATACCTTGTCCTTGCTG
+
;;;=I(I)6;4F&7I<,&95<6=7;57I)I(<I-&I(773776;I(=I*947I0'I0';9I1':?8I)6698679<8I(4:@=68:I-&I(7=II3+':846I2(96H'5:381I*;<55I(I(I-&I(8I:+&936I/'79I(I'I(5958475I(456I(I(I(18::37I)<6;G'67;74I(I(7>I)74I)I(I)74<093I):2I(48:I1(87684I1(8:D684I(78979;9?893I)I0'7I(78I(7I/'I(8:7/447:8>8I(I)8I(6815I(7;:;4736%I(3652:86:65I(9H'I(3I(65I(7;;I)8C8I(G'4H':I(9798@I(8B96I(I(&45I(6=897>I(I(I)I(59I0'I)I0'99I+I(5697I.&672:688;4I(I(>9F'I)I/'6I)43I(8289798I,I.&5472:6I(I)07I(I(4686
@simulated.270
GACTTACCCTAATGAATACAACGAGCAGCCGACAGCCAGTGAATCGCGTGATACATTGCCTTGGAATCTTGGCTACATTCGGTTGTTTGCATCGTCTAGTAGCTAGGTACCTGGACAGCATAGCATAATCCACCCCCTCTCCTAGTAGTATTTAATGCTCATGGATGGCAGTGTAGGAGCGACTAGATTTTTGTGGCAAATCTTATACTGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCGTTCGGACAGCATAGTGATTCGGGGTGTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGCGAGCGAAGTCCGTTTGGTGCTATGTCCCCTAACTTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGCGCTC
+
97;G';I0'8H'58I'936G'77654<8I(9694<I*47;9I'78487867387=I';I'I*H'I*33I(I*96877I(4I'F&;I1'6795843452858876:I(95I'?I)65::3:878517I'9I(5II2*&<98I'79<03::7I.&I(6888738G'8;G'767;976I'558658;36;II3*&:6I)>I1(4:I(75%;<4567;:I)577548I'5666H'4677:4343;7<3I(543F&6858099783(I'<H'8:9774;<;:9:G'7I@-'23I,3I/'I;+&;9I(245I.&I(66<:8:7H':6I(G'7I6)9<7897I(74I'&I0'I(88517669I8*&:I*6I9+&<I4)6554I(4356::876567:I;+&85II1*&:9:22:I'8::I(786I(<5;296
@simulated.271
AGCAAATATCACCTGTATCATAGTGCTTGAGATCCTATTTTCTACTCCAGGTACACCTGATCTTTCCCATTGTTGAGTGACAGGCACCCCTATACCAGAGTCGTAAGCGAATGCAAGTTCGGAGTGAGGTACTTGACAACCGTGGTCGATAAGTCAACGGGCCGAGCCTTGTATCATGATAGGAAGCTCGGTCATTCAATTCCACCTATGCCCCAGCAAGGGCCCAGTTAGTCATTCTCGATCATACTGTGGCAAGGGACGAAGGTCTCGGGGTGGAATACAACGCATAGCCGTCTCAAGGGGAGTGAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCGATACTACCTTACAAGCCGGGCCAACGCACTATGGTCAGCTTATGTACC
+
796I-&9:8:8I(:3%56<8=;917:H';:8:6I(6.IF/(860:3I(5I)7869I(98:>6I-&I-&;I(9H'728:788<I(83I=,'7:=5I(7487:5;6I(864I(5:4I(7I'5I(385=6G'885I(498I(I(;7G':5748I);;8I(7I.'I(557I(F&64826:;57:6I(I'7547H'?6:I'5I)G'I'6H'=64:I>,'99<F'I/'I.&78I(46758I)39:=985;98:5=9H'>I)I/':7%H'I';77:I=,'9I(I(769I(8678786I)68698I(I<,&6<;=45I0'<5I)707?I(<43576::9756569I(>:546256G'I'52G'9E&I-&I(G'9679;849I*45388G'69<85H'
@simulated.272
AGGACTTCGCTCGCCCCGCCGGAGTTCTGACTGCTTAAATCTAAGACCCCAAAGAAACACCCCGAATCACTATGCTGTCCGAAGCGAGTCTGCGGTCACCGATCTCTGCGATGCCATGTCCGTATCAGGAGTCTCAGATAAGATTTGCCACAAAAATCTAGTCGCTCCTACACTGCCATCCATGAGCATTAAATACTACTAGGAGAGGGGGTGGATTATGCTATGCTGTCCAGGTACCTAGCTACTAGACGTATGCAACAACCGAATGTAGCCAGATTCCAAGGCAATGTATCACGCGATTCACTGGCTGTCGGCTGCTCGTTGTATTCATTAGGGTAAGTCATACAACTAATATTCACTTTAAATTGACTAACCG
+
8I(5:H'88557=I;+&7I(I'66G':85/(7;5I(I.'88:I)86I?-'I0'6I.&68I<+&6I'465:=6686>84I(9H'58?78347::G'354I)<2636<646?6<8I)7778I(5778:3H'664=;24533I';7I/'7I(9:II0)&;888;46;87I(9565674I(53I(768<998I)I-&56394485I(756II2*&3I*7I(9<453=258596I';I(92I(5<86956>:;1532;:88I+9I)I(<H'8557/I(D8:I(F'H'I'3I(6277886==15BI(4887I)857:5I'<5;5:07I)4;8H'88I(;I0'2H'<:88=7<I(35I*66I(773I.&I.'I)839:I(I(2
@simulated.273
CTTGCCCGTCTGGTCTCTTAAAGATTTACCATTACATGCTGGGTGGGGGTTGATTTTGATACTTATCACATAGTCACGATGTTAGTCGGGAAAGGTAGACTGTTCACATACCGGTCTTTCATGTCATTCAGCTAAACTTGGTTTATAGCGGTTCTCCGAAAAGAGCAAACTATTCCGTAGGCTGACCGGCAAAAGTTAAGCCTCATCTATGTCAATGAAATAGGACCGTTAATCATGCCGCGTTTTAACGGATACCAAAATCACCCAGTTCTTTTTAATAGCGGGGTGCCAACCTTCCTGAAACGTGGATTAATCGGGCCTCTGGTACCGTCAGTTCTCAATAGCGACAGAACACTGATCTGGGGGCCCAGCGATGTGGGCGCTTGCC
+
<I)5I0'7=78I'6:79I'I1(45I/'9I(;I'8989=<7I.&3II3+&I(87I8*&>8;51I(=4696395885743938I)59A8I0'I/'I):981717I)764457I)H':6I0'93328;;I(996:7I-&6H'I(I4)9;526G'F&67F&6I=,'5889I2(555I)I)8*;H'9778I(F'5IE/(8F&I)6H'68:>=4;45:7H'8<I1(8;I)9I(4I(I)87:3<I(77:I9*&H'6I'54;I'I9+&59;I1'78I(2II1)&I(4:98I=,'71I(I(I*I(I,:8I1'=69I(7I(G'66I-&I'988I*=7I*:76<8H'698I'369588<4<I)497763:26II3+&I0'99:44314I2(6<6I)3D&
@simulated.274
GTTCCGCGTGATTGTCCATGAAACACTCGGGCACCACATTCGATCGACACTACCGGGTGGAGCCTCCTTCGCGCGCACTGTTCCACCACTATTCGCTATCATTCGTACTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGCACTTCAGACCTTGACCTGCACACCTTGGCCAGAAAGGAAATGAAAGGTGCAGGATATGCATCAATTACGCCTTAAATGGATCCAGTACTGCCCGGGTGTATACCTGTCCTTGCTGTCTGTGGGGCTTGATGGTGGGCATCTCGCACTCACACAAGGCTACGAGGGCATGGCGGATATTTTGACAGCGTTCATCTGGGTATGACGCACCTAGTAGTGAATAGAGGCTCTACCACAGGGTACCCGGTCGAACATGGCTAATAACTATGTTAAATAGGATGGCCAGCATGCTCC
+
3I(I(865582H'57I(4=6I.'99397I1'89I)896F'(67:597<86:=I(I1'6G'99I(6I,I(85854?836?7I(I(5I+6674F&76443A9@H'99;;786432I'5I(I'=I(53I'5:<I*672H'E&:I(8I)6;543H'9657I(I(68I*89<<83I)I'I(I(44I-&H'I3(58I-&I'6=54I,66<=466<5G'I);'6I'I(I-&6I(68H'77:977:I3(I/'374:8<I,D5:I)I(=599:6<84I;+&8I(<:9I)7I1(699;83:957::5577H'I*:81668I/'68<I'5G'58:I=,'6<86784I(59216I-&379786893I(69;53536I'9<36I(5456&I)=46I3(94I3(I(;95I)=37I,57I'8I(;<884I(I7*2=I(56I(I(74:39<56I(
@simulated.275
GCCATACACTTCTGGCAATCGCTTATTAAGGAATTTTCGACAATGCCCGATCTATAATCTGGACGCACAAAATCATCTTGGGATAGGAGGATTCGGGTGTGTCGCAAAAATGGCCTAGCAAACCCTGTCGAGATAGGCCGGGTGTCACGTCAAATTCTCGGCTGGATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAAACACGTATGGATAAGGGGATACCAGAAAGTAGTTCGGAAGCGTTTGCATCATCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACTGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCA
+
9F&<84777I'7:I*8I(=84:I):F'G'I(H'I;+&929;I(4;I-&6<59647I)348I(;66;84I8*&98896I'I/'877I(7I)5I(7I/':4:67:89II1*&9I'F&9879I-&I1(9587899596I'I)I-&<?:476876I.&I)769H'<9I'78I0'I(;9:439<I)9:9I(364>58I(;1:765380E&:8I(8I(I(I(98IB.(5:58;58G'9=I'I;+&848I)78I/';787I,7I)I)37=I-&:75579D9;3:1I)5I(I)<88=<77:I4);9398I.&38;95;6G';7;7729I-&=5I0'9I(56<83<47I(:7786833I(67I'95I)576I(>
@simulated.276
CCATGTTTCCTAGCTACAGACGAAGCCCCTTCTATCTCTTGTCATTCACCCACAGGGTGCATATCGATGTACATCGCCGATAATCATTCGCCAGGGATCAGCGGCAGTGCGACACGATCCCTATAACGTGTATCCCTATACACCCGATCATTTGTTATAAACTTAAAGTGTACTTATAGTGCGTCAGTAGACCTGTGCTCGGAGACAAACGCTATCCGGTTTCCGCAACTAGCCCCCAACACCAAGGTGCGCATGGAGACCCAGGTTTGGTCTTGAGCGCTCCGTAGTCGACAAGGGCCGCTGAAACACGGAGCCTACTGAAAACGTTCGAATTAACAGCCGACCGTGTTATAGTAGCGGTCATAATATTGGAGCGTATGACGTCATTGCGTTCACACTGAAATCGATCTACTGATAGTATGAA
+
I(985I0'I(886999756732H'4I;+&I,:<;8=95I(5567F'35I.'2:4I-&:7278734879929646?6I(176I'345I)<6I(7I.&:726.4I)<89/88198756=9I0'8:4I(1722558I/'9=5962I1'7775:I.&;F':;I7*:I(I0'<88775I'86469767=:;94643I(986<9:9I(39:7I.&77::17I)I'I2(I)54H';;88II0)&H'2<I'I'H'39499=9I+889I.&7I'I.&I(<4I(4<:66<9I*5:9589456I'I0'I(6:38I.'=99I(:4I(%9&88I>,':5F'99I(G'I(>=:I)89I'947I(75677977I(5998I(46E&I*8;9:6<6B4%8<9;I'979H'5595:67I1(:>55<15C597657=8:59G'
@simulated.277
CTCAACAATGGGAAGATCAGGTGTACCTGGAGTACGAAAAATAGGATCTCAAGCACTATGATCAGGTGATATTTGCTAATAACCCAATGTCGCCCCTCCATGAAGCCGCGCACCAGCTCCCTACAATCCCGTCAACTTAGCGAGACGAGAGGTAAATTGTGAAATTACAATGAACCTTGGGGACCTCATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCTTCATTTTTTGTAGCCCCATCACCAGCGCTAGTACTATCGTTGTAAAGATCTTGCACGTAGACTACTGGCCTAGCCCTAATCTACGCAACACGAGACGGTACGAAGCCTTTTCTTTAAGATTAACGTCAAAAGTCGTTCTACCCGACGGGTGGTCGCGTGAGGCT
+
:76I(5H'5I-&I,:7255I(5949I)9I)4895&5II3+&;5I'7;674I(77728769882:H'4455;I0':<8I(3I(I.&I(82619I9*&<F&:;:I)4I'9;7?;I):4<8I/'663I)3I/'?78F';G':9?;48439788I(<I0'I(812I1(I(48I)75I)I(I'I8*&;I(74BI/'I(6<76I(56758;I)@6I':45:7I(999I,I(6=II<0*&4;87I;+&976:I(:5774'1;646587>3I(7@I/'9<=5G'99387974;897:9I(G'665I0'5I)395=246I)347)7788I(;8<3I'7H'I:+&:I.&I)67E&I);974I<,'4->(I(39;I.'&78I1(8I'8=86>>;8I(64
@simulated.278
TCCCGTCAACTTAGCGAGACGAGAGGTAATTGTGAAATTACAATGAACCTTGGGGACCTCAATTTGGTACGTTCGACTATTATAACTGAGTTGAGCCCTTACATTTTTTGTAGCCCCATCACCAGCGCAGTACTATCGTTGTAAAGACTCTTGCACGTAGACTACTGGCCTAGCCCTAATCTACGCAACACAGACGGTACGAAGCCTTTTCTTTAAGATTAACGTCAAAAGTCTTCTACCCACGGGTGGTCGCGTGAGGCTTGTCTATCTGAGTTGTCTGTGCTCACGGGGGCTAACCCTTCTGTGGCCCGGTTAGTCAATTTAAAGTGAAT
+
8I.&197I);I):9:<<6:46659G'2I*I)799I1(H'38H'<8H'I(I'I;+&7I(86I(I.'I)4856E&3665:4I(86I)>9410I)977I-&H'+68II:.)&89:9I?-'6665I(;44757770<=8978I(35I-&76'96H'97968:4664::8=I'I);69I-&6I(>25>40:H'=5<7457I'5898I(1I(I;+&2I,&I(56I)I)6355I8*&4:2I(857I-&58I0'8I(469778=;I'8I'989>=4:5768I'<67758<56446II1*&72H'I.'I*9967I'I.&H'I(64;8I(I.'I0'564I)9
@simulated.279
CGGGTGTCACGTCAAATTCTCGGCTGGTATCCCTTAGTCGCATTAGTCCATGCAGAACGCGCACAGTTGAGGCAAGGCCGTAAACACGTATGGATAAGGGATACCAGAAAGTAGTTTCGGAAGCGTTTGCACTCATTCTGTCGGTCCTTAGTATCTATTTCTCAGCCCACTCACGAATACCTGTCTTTCTCCCACCTATACATGAAGTCATACAGGTACCTGTTCGACCAGACCCCCCGGCGTCCCTAGTAAGGATTTGCACAGACTCAATCTAGTCACGTCCGCTAGCATCGGAGAGGCGACCATAAATGGACTTACTGTCATCGCGGCGTAGGATAATCTACGGTTGCATGGTTATTTAAAGGCTATCCCGTAGAC
+
2I/'8<6669964I1(I)>>;I'97G''4>I1(I(7695636I*;55I)667432I(657668563I'5<H':I(I'E&68I6)8857294I(4<I'I6)8:5I(62I0'77:6I5);I'I(232I/'936%76<I(:2258D&8I(H';5;:827:I/'672::I-&:2984;:I(;7E&68;7I1(88I0'6I)857:?<=6I+32<964=:G'9<I)89I(859I*685II</*&I(3:8I.&6929I)H';I-&7664:8=755I(77=694;7<9/I(38;:6?6:7I)887I(;56I*97I1(6I(6=I(635:4;33;7:G'88=:E&77I(988;7I)I(5;:7I(I(5I1'I1(F'207:I/'74)858
@simulated.280
ACGTGGGGGGTATGCTGGTAAACTTGGACAACATGGAGACAGGCACTGCGAGCCGCACTTCGCCTCACGAACAGAACGCCGTCTTCATGATGTGAAAATGGGGGGACCCTCAACATTACTCCATGCGATGGGACCCAGTCAGCTTGCTCGGACAGTAATGCACGGCAACTCTGGAACCGTTCTGTTCGTCTTGCCATGATACGACGCTTCCAGTATTGCAGACATTGGATGGCCGCAAGTCATCCCCGCCACTAAACGGATACATAGAGCAAGTAAACTGATAATAGGTGAATGAAGGAGGTGATCTTTTTGGCTAAATCGTTTGCTTTACGCCTTAGAACACGGATTTTGCGAAGATAGGCGCAGGGGTCTCTAGCTTAGCTCCATGAGGAGGTTTGGGGGA
+
789<II8-(%899987I*4I2(9G'H'88I(7<5I*8595:I(:61188987H'9857I(;1I'<:674I(:85I(9>I,>3:E&66;:6384DI;+&5II</*&7I/'73I)38H'599I'69;9945I/'6I2(86:5;6;I)3873I(=4369I(57769E&3E&4797I(I)I+5I(771I(9:8:I(;I(38768=767638I(I(9&77I'2;7;976G'I*88I(I(88H'51895I=,'9I'548I/';H'398;3665663I(;7I.&77:94I(8<I(56I(:8I(I(7I'7868<II2*&H'9DI1(676I/';4I1'D69I)I(9:I'>75F'8I8*&166I)0880I)7;:4ID/(734445;6I'4778I*:779G':G'I7*IG0)%9
@simulated.281
CACACAATGCCATGCAATATAATTAGATGCCTGCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGAGGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGGAAGATTCTGCCTCGAACATGCCAGAAACGTCGCAATACTGGTAGTCAGCAGACTAGAGAATGAACACTCTGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACCTGGTACTGGTGGGTTAACTGGGCATGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCAGTGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATGAACGCGAGCTCCACGTGTTTTTCACCACCACCTGGCATCACCGTCTTAT
+
66475I(74I(;6?5I(;58I(I(96845H'57I'II1)&5;;376H'48AI(>7695G'4867I(1H'I(;56;7I/'588D&I0'7I0'98I'7I'<I)I(8I(<89G'6:2I8*&I)5;G'297I)A4?I)4826I'78I0':44779I)7345I(583799949;58687:8H'9:I(8=2::;I'8>:9:7I)I(56H'3476695;75<1G'9G'/7;459:I(8:8I(9I);896G'3I1(I(I*:9I/'7<6I(868>6I1(I0'7:I'53I/';I(62;5<:56G'6=5<;G'8I)I(:&6=98:I(:I)554I'I'589<;4<89I)546593I(:9I)846<575>I(97685IH0)%56G'6I,9I(8E&<:656I,<8:I)39
@simulated.282
GCACTGTTCACGTATTAACATCGTCTTAGCGGGATCCGCACGATGTCTCCTAGTTTAGTCACGAAACCACGCCTTGCTTGTCCTGGGCAGTAGCAGCCCTTGGGCCCAATCCTTAAGGGCTGGCCCCGACAACCAACTATTGCGGCAAGTTCCACGGACCTGCAACTTACGTACGTGCTACTTTGCGTCGCAAAACGCACTTGGGTTTTACGAACTTCTGCCTAAGAGCGGACCGAAAGCCCTAGATGGTATTTTGAGCGGGGGCCGGATGAGTCCTTCGTAGTCTTCAAGTACAAATCCAGCCACCAGAATGTACCACAGCTGCATACTATTGACCACGGGATATTTGGAAGACTGCGGTTAC
+
796894H'9:82;<I)I(957667;H'778I6)98G'54;71689176I'868I4)96;:574I3(H'348H'I(78I(78G'9I1(74-64;938I-&H'I.&I0'I*9I(I+I'I1'97I(I:+&79/I)I(I*588I':8I(4I)/I,E&47I)2I(66;I'5I(15<143917:429I-&9<57796I;+&94675I)I1'I7*&8:8I'7I)3:5I(5G'5254I(5H'3I.':I0'92957H'9;I<+&77;8II3+'I(I):65;&;I(I*66429:8I(9I)78=9I.'7F&63G'5H'88I(436>I):7577697::78>4I)76F'37I-&;73I1(I(I)=<:382I)G'<8
@simulated.283
AGCGGTGCCATTCCGTGGTCTGTTTAGCCAATAAACCGTTATCACAGGTGTTATGTTCTCAATGAGTTAAACGGCGAAATTTACCACCGTTCATAACCCCACAGACTGCGCCACCGGAGTTGGGCGCATCTCCCGAGGCAGGAGGGATTAGTTAAGTCTGTCTACATGTTGCGACAGACAAAACAAGAATCAAGTTTCTACAGCCGCCATCTCTAACTACTTGGATTTGCCGGCCCGCACAGGCAGTACAAAGTGAGAGGAAGTTGGTCGTCTGCTCGTCGTACCAAATCGTGCCCGCGTTTTTCCTTATGGAAGATAGTGCCCACATGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGCAAACAAC
+
45:E&:6I(8I(I'99I(8948I0'88I(E&5I6)I':I'986:46E&62I)3;;I(997I(9::3I'I2(3I*<&I/'I2(7I,3H';I)982H'I9*&5:59:9799<E&3I(H'97I)I2(253=:89I/'51I(:8I(:I.&3H'6:I)I)668:9<365;848I)5;9?:86:6I<,'@I(3I)9:I)8I-&885874H'7H'675677H'737:I(G'=I/':I(I(I1(65798I(7?2967I/'9866:5I'I(9I'H'6374:5738;863861I(I/'865?;I.'6;9II1)&I(I*75H'I'<;82673I.&865::7A@4I'879792657I0'I)56@<77334I(::67@96596I0'47564:9I.'<I(6685I(I(I(9<I:+&<54H'I7*8I/'8D&8
@simulated.284
ATCATACTGTGGCAAGGGACAAGGTCTCGGGGTGGAATACAACGCATAGCCGTCTCAAGGGGAGTGAGCCCTGAAGCATGGTCAGCTGCGCATACGTTCGATACTACCTTACAAGCCGGGCCAACGCACTATGGTCAGCTTATGTACCACCTCCGTTACACTTAGTGTTGTTTGCCCCGGCTGTTTTATGGCCGGACACGGACCCACGCGACTTTGTGCTAGTACAATACGTGCATGGTTTGATATCATAGGATGACATGTGGGCACTATCTTCCATAAGGAAAAACGCGGGCACGATTTGGTACGACGAGCAGACGACCAACTTCCTCTCACTTTGTACTGCCTGTGCGGGCCGGCAAATCCAAGTAGTTAGAGATGGCGGCTGTAGAAACTTGATTCTTGTTTTGTCTG
+
8<:95848<>I)<H'I-&79I(I)7972I<+&8I(E&853G';19;:87I*69579H'I;+&99.:97I1(97I'8684G'587:6;8889-87<7I(66679997I(I(7:I(6I(I/'I)I(:;956898G'77688H'6@989I(:F'=I(9I(;672E&:944I(7I-&7IA-'I(577I9*&76I(I)I)<9:3H'<I/':?75?=:I-&363:64697:I(97;214><:H'I-&7:978735;G'596:9:;73I/'6977537I(I(89H'I(II2*&6=9I/'6888=I2(H'::<6=754269545:<I(H'6I'I(588389I1'<874;4I(:7946I-&I(I)7I1(6F&H';576I(772:67I(4I(3745:7I/'6G'69I'9I(<I<+&44=96
@simulated.285
CGCGGAACCAGAATGCCTTCACTCAAGCAGGTCGATGAAGGTTATAGGCTGATCTGGCCGGCATTTCTCGGGGTCAACCCAACCTAGTGGATCGATTACGGGATAGCCCCCTGCCTTTAGCTGCGAATCTCACGTATGGCGCGGGATAAATTTCAGAAGAACAGAGTCTTCCCACCAATCGTCTCAGCCCCTAAGACAAGGCATACGCTGGGTCAATGGATTCGAATGCAATGCGACAGTCCGTGGTGTAGTAGTGTATAACTCTGAATAAGAAGATCCACCCATAGCGATCCCGTTTCCACAGGAACTAGCAACGGGCTCATAGTATTGTTGAATTTCACGATCGCGGGTCTTACTCCGGGCCTCAATAAGCGAAAAGACGTACCGTAGAGTCACTAACCGTGC
+
996I'E&H'80I'82I)I(6948<I(494I(6;29:9I(I(I(567E&775667>I(G'H'88I-&979I:+&%8I)I/'I)I(4566G'85:=4I'74I.&9695IH0)%;;I(I/';<37067I)9:596&7893I)672I0':7I-&I0':9<H'4I(<53;967H'I0'6I'I(9==66793:I=,'5I(8=5I)I'76;;;818I/'<<I'9I(4I)=5I(:97I(6276:9896I'55G'9797366::9495I(756=3G'6I(7G'776I)6I.':=8:8;29I1(7I4)I(41=G'I)79885I(7I/'66965:6<2I'4I'8I(I3)8987:8846I/';8I(36;I)I/'I'75H'5I(685I8*&6842;7I(%9955357=;6I(H'<<48
@simulated.286
ACTATAAGTCGTCGGTCGCTCGCATATCGTAGACACCTACCCTGAAGGGCTATCCGGGGTGCATCATGTCGTAAGTTTTATGAACAGAGAAGGTCTGAGAAGGGCCAGGCGGACACCTGCCTTGAAGTGACGACATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGGTAGTCACGGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCCTACGCCGCGTATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTACTGTGCAAATCCTTACTAGGGACGCCGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAG
+
8>59:H':;<95:E&;::<49;85<3;6%::<78:I'74I/'49I*I/'6453I*I9+&39575655:)6;9G'6I9*&878I(6=;68I(I'755885I(I0'I*6F&8I(667I(8>I)H'9I)5958;613;8I(6:?64::24:96<27I(<7984=77463I.'78=96:9;:97795748I;+&5;<9:27I1(<796I(I2(I/'3I(G'7654H'I(895;7I)07G'775:I'12:%89988568I(:6I(@I3(6?I'::9I)565I(8677682:7I)495=8667;5=I)4997%2=6388I-&:I(H'9987I1(696I(II6,':97I)848H'58I)77I'8:66264>I)98975:78I)8I/'8:
@simulated.287
CTGAGACTCCTGATACGGACATGGCATCGCAGAGATCGGTGACCGCAGACTCGCTTCGGACAGCATAGTGATTCGGGTGTTCTTTGGGGTCTTAGATTTAAGCATCAGAACTCCGGCGGGGCGAGTCGAAGTCCTTTGGTGCTATGTCCCCTAACTTTTGAAACTAGAATGCGCATCGATATAAAAGTAAAAATCACTCTTCTAGGTGCAAGCGCTCCGGCTTATCGTCCATCCGACCAGTAGGGATGTGCCTATGCAGTGTGCTACCTATACTTTTCGGCTATGGTGACGGCATACCAGAACGATAAGTCCAGTCGCTGGCTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGGATCTTATGTCTT
+
479:9<4>I(7945:8I*9789I(2>;3793177969I(5A>I(>0849>764;I(4I(:358:873::39I(:I6*58I+7I/'I=,'3=D&372I.&F'667951;I(4:G'I(6I@-'789;&75H'73I)I/'H'7697544<I=,'8I)7I?-'<I/'9589I(58484:9474789I=,'67IH0)%<<6984I(548I(881I(66366I(I'8I'85;7;I):3I(88I(354:I/'75894G'87586926977648I'4:;;5I:+&>G':769I(57=4I)5989I,::I)5:55I(9%H'84988:9I(1I(349;65;9I(9<6;;1I1(8I0'5I(1I(I(H':89I(6I(3=::136982997I(7=9<5I)E&I(5I/':97I(:7<65I(
@simulated.288
CTCATGCGTTAGTCCGGCGTTATACATAATACTACTATATCCGTCTGGTCGAGCAGTGACCGAAGGTAGGAAGCGACACACAATGCCATGCAATATAATTAGATGCCTGCCTTTTTATGCGATTACGTTGATACGGCTGCTTGCCGGCATACAAATGAGTTTGAAAGCGGCGGTAACCTAATCTAAGCTGGGGAAGATTCTGCCTCGAACATGCCAGAAACGTCGCAATACTGGTAGTCAGCAGACTAGAGAATGAACACTCTGGAGTGCACCTTACGGCTGATCTAGTGACCATTCGCAGCAGGATACCTGGTACTGGTGGGTTAACTGGGCATCGGACATGCCCTTTGTAATGTTTCAAGAGCTCGCAATAGTATTATTCCATGATACCGTTAGTGGAATGACTACTGTTCAGCGTAATAGAACGCGAGCTCCACGTGT
+
;645688<H'5;:E&H'74I(6;6566I(<5<9>764217I*5933I)7&38459965:I(8F'I)<4I'I(8775A7764I)87I)5696I(266G'I':7559I'78I(II2*&=793<6G'79;I'<::66I(7446I(4G'I(<96;4I.&6986I.'5I.'25H'9I'6I(I':H'786I'3:3I;+&I(72D&63=H'606I)3/<4I(78I/'88:3<8G':773I(9:769:3758>55>55?H'86I(97:966I'0:8:48I)I)58I)5;=678788965I(9I'<;7:726I)856I(2I'6<59I(;I1(I(G':4I1'668'I(88699I/'I/'99I(94I/'5I(4=986796I':6575I)8H'I)658>9<I(8I*2<8I*F'47;88;:8:G':9;2<8I)826I)92:689A9I)088;96
@simulated.289
TGTCGACTACGGAGCGCTCAAGACCAACCTGGTCTCCATGCGCACCTTGGTGTTGGGGGCTAGTTGCGGAAACCGGATAGCGTTTGTCTCCGAGCACAGGTCTACTGACGCACTATAAGTACACTTTAAGTTTTATAACAAATGATCGGGTGTATAGGGATACACGTTATAGGGATCGTGTCGCACTGCCGCTGATCCCTGGCGAATGATTATCGGCGATGTACATCGATATGCACCCTGTGGGTGAATGACAAGAGATAGAAAGGGGCTTACGTCTGTAGCTAGGAAACATGGTGACCCCGAAAAACAGCGGCATGGCGGCTGAGTAGGTCCCAGCTCTCCGTATGTACTGTACAGTTTCATAACGCCGGATGTCTATCATAGGGGGGCTTTCTTTTCACTCAGAATCCGGCAAA
+
6;87=9;346I(4566;7;I(89I(I,I(3I,7;6H'565:<47I(I)H'5:I(II0)&8:84H'82I(I3(I(I(67:=68I-&5;17I(23=<686I(:7:7337897;77:77I)855847I.&I(7I7*&98G':I0'18777I.':46549I.'99:9692I)9;8I.&:=4<95:699;636I(673568I0':I*96I)68;I(586I(698<538;46:95776794I0'96<I1'74I(9:53I(5851979I/'I@-'8G'&69;:;7878668I(I-&4:1I(49?I=,'7II1)&5984F&81:I':I)9656898H'=I1(468=98F'64:2<;:>85:4786I-&356G';7G'H'87766956:9:6II</)&;I1(;I<,'98385;6I,6I(E&:I4)
@simulated.290
GACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGGCTCACTCCCCTTGAGACGGCTATGCGTTGTATTCCACCCGAGACCTTGTCCCTTGCCACAGTATGACTCGAGAATGACTAACTGGGCCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTAGACTTATCGACCACGGTTGTCAAGTACCTCACTCCGAACTTGCATTCGCTTACGACTCTGGTATAGGGGTGCCTGTCACTCAACAATGGGAAAGATCAGGTGTACCTGGAGTAGAAAAATAGGATCTCAAGCACTATGATCAGGTGATAT
+
44I)876=3683I(I)I.'I'=I(33I(I)78465676I(7/9785::;:878=5I(6574F'58I.&949467I8*&I(83972D&488::69I(864I(I(4I7*:376I'I'7:I/'I(=I(8:6698697%46336I(<6967I(;8I0'I0'I)626I;+&<46<I'6G'F'I'7H'899I)09;6I(H'687;=8963;6I)I'798G'I1(8I(&797H'6::87I'56I'I(57:E&7;4I'6<868I'8I'=I(668I(;:5I'=676::57I(6:58I=,'57I(88178;=9I(8I(:I.&I/'55657H'26=7I*2I(5;256IH0)%72I)89576H':848:6897766I(857;74
@simulated.291
TACACTTTTCGAGACTCACATTAGACATACGAGTCGGTACACGGAACAGTTCAGAATTCCGAGCACGGTTAGTGACTCTAGGTACGTCTTTTCGCTTATTGAGCCCGGAGTAAGACCCGCGATCGTGAAATTCAACAATACTATGAGCCCGTTGCTAGTTCCTGTGGAACGGGATCGCTATGGTGGATCTTCTTATTCAGAGTTATACACTACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTACTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATG
+
:>6=1I<,'439;9643979I(=99765695<79:F''4866I)I(78%F';8:I*F'I(927;5<I(I)9986795<85I(:70867I=,'668I(6G':9CI-&I)78<I(96I0'8:76747:7I.'I(2I(;I)539799<08I/'<I(;5=:9I(I(378F'I,6I.'5;77296=I+9I'478I(7I(3I(;9953F&9:7:4743;4699I(94I(688:565<8I(759I(;6G'8F':I(84I3(9;=:6945I(F&<7?I(8I9*&6<5;89798F'H'5I/'I(7697887I(&7I)167I0'I2(66I0'415I'8;36265>9I(56:5647I-&I(67II1)&9598I/'54I(6362;G'6958I(G'I.'F';I;+&585I.&9:
@simulated.292
AGAGAGTCGAGTTAAACGGGCCAACCTACTCGTCGTCGAGTGTTTACAAGCATAACTTGGCACCCGACGGGGACTAGCGCTCCTTTAAATGTCCAGCACCGGGATGTGTGCGCATTGAAGGACGTTAGGTGGCCTCTATTACGCCATCGAGAATGCGTTCGCTTTAGTGACGTGATATAGTGCGGGGGCCGTGATCGCGGAGTAGGTTAACACCCGTCGCCGATTATCACAAGTTTTGACACATTCTACATCTACCTTGGCACATCCCGTTTCCCGGTGGGGTAGCTTCAATCGTCTGAGTGGGTAACTGCCTTCGCACTGGTCAACCTGTCGCGTTTGCCGCTAGTCGGTGATCACTTGGAGCCGCCCTACTCCTAGCGATCGTCA
+
57555637697I'I4)9I1(I(I(I(7778976:2;:42:0CI.'89I)=657I):I(I*;4I2(5%8I8*&6957:96;7I'I/'I/'385I):626G'I.&743;5763=:5I)7I(I(439I(8I(:I'H'49<7I(466I(94146;G':=58H'168I.&8869877917;7594;41II1*&I(835<2;7<I(367;I(I(E&3;I-&7959I):;I)76877I(7IC.(<61;62I(97874<3:8I'I)I(64559I/'4I0'I-&I(8I:+&6885I'<I(8;6:864767I-&:H'.8@I'I(7<=95<I(76I(E&8964785I.&7F&744758:H';;76:<;F&I(57I)2I.&8:77I)59786516:8><
@simulated.293
TATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCATGGAGTAATGTTGAGGGTCCCCCCATTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAATCACCGCTAATTGCAAGGTTTGATGGGTGGTCATCTCGACATCCCATCTTACCAAGTTGTAGTTATCAGCGCTGAGTCCTGCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCG
+
9<9=96I(0I(464<I'78;I)6I/'I(I(2898I)<I)58936I'5:9;8G'4567I(797;25:I1(3I.'7B4;7<6I)472E&39I(65I0'7II:.)&3I6*I(68;:3663I(989I.&7=I(479I(:5798I(:;I(75=<I)169893669I(3981>G'668I(96I'H'5I3(9I(355>98II9.)&8895:33635I'676;I-&:88I(6I(4591I(38;7I;+&8I'I+687I)94;I'I(15I*I(I.'755I-&CH'69569:6:3932I.&695I(:I(I(8I'8?96I(4C7;66896;858I(5<;9=I'I)9:8I-&I/'5>7983I(6888I(I'H'=;44I(I(577;868I-&69I.':
@simulated.294
GTGCCCACATGTCATCCTATGATATCAAACCATGCACGTATTGTACTAGCACAAGTCGCGTGGGTCCGTGTCCGGCCATAAAACAGCCGGGGCAAACAACACTAAGTGTAACGGAGGTGGTACATAAGCTGACCATAGTGCGTTGGCCCGGCTTGTAAGGTAGTATCGAACGTATGCGCAGCTGACCATGCTTCAGGGCTCACTCCCCTTGAGACGGCTATGCGTGTATTCCACCCCGAGACCTTGTCCCTTGCCACAGTATGATCGAGAATGACTAACTGGGCCCTTGCTGGGGCATAGGTGGAATTGAATGACCGAGCTTCCTATCATGATACAAGGCTCGGCCCGTTGACTTATCGACCACGGTTGTCAAGTACCTCACTCC
+
579I0';84574544I(5:8=:6655I.&F'6685:7;;3H'73447:7744I+78977=;I0'@I(64=:I)I'I(89I?-'559H'I?-'4I-&7I'9485G'9485I)8I'3I*9I(59715I'4:697H'29787996I(I(I/'I)9I)93I(I'36:95696I(67977676<76979:I(245:I)96I.'997795I9*&I(=8773I(6869658D48;I'I(4I@-'6754I(E&5:I0'I(:I(58787665;8969@I)99:;8I(3:I2(I2(I(:8<I7*&>679I(7I(I)I(5H'689I)8497G'I'<6:<:93:9;6I(G'656I(I0'5I)757G';:594I(82I*H'33;H'7=;I(;7786I(
@simulated.295
TACTACACCACGGACTGTCGCATTGCATTCGAATCCATTGACCCAGCGTATGCCTTCGTCTTAGGGGCTGAGACGATTGGTGGGAAGACTCTGTTCTTCTGAAATTTATCCCGCGCCATACTGAGATTCGCAGCTAAAGGCAGGGGGCTATCCCGTAATCGATCCACTAGGTTGGGTTGCCCCGAGAAATGCCGGCCAGATCAGCCTATAACCTTCATCGACCTGCTTGAGTGAAGGCATTCTGGTTCCGCGTGATTGTCCATGAAACACTCGGGCACCTACATTGATCGACACTACCGGGTGGAGCCTCCCTTCGCGCGCACTGTTCCACCACTATTCGCTATCATTCGTACTATAGAATGGAATAACTAACACTTCTGAAGGTCCTCCAGCACTTCAGACCTTGACCTGCACACCTTGGACCAGAAAGGA
+
459993<I(77I)58499:9;4I)68-G'63I+4I*4I(66I4)3=87574>I(I(%76:I(8I:+&647976564I)I)6I/'I(7880379F'9I(478I.&I1'85I-&:57G'7:8867686F'8;68<95I.&I(78IH0)&75>3I-&36I(89747I'9985I(I(I3(H'8I>,'467I2(9=I)H'I(5975237I)377G'I(I'75:765I(026I(8=<68I(E&:6H'4:I'I'I*62:42?G'3;H'48:I4)39676I0'65I(%5;7I+39699?8<5:9I'I/'>I(-8I(7I0'I(;/3:9::4>58I'I);I)8;33I'><6=6898F'759227<;6;I)5I(I':G'83I(646I(78:I(I)8G'4I(66:6:I'949.I'I)57I(6;<37<I(I)H''I(82I2(E&<
@simulated.296
AAGCCAGTCGCTGGACTTCACGCTGTCCTGTCATAAATAAAGCCTAACCTTAGATTGTTCGTAGAGCTGATACCGCTACTTGGTTAGGGATCTTATGTCTTCAATTTGATCTGTGCTTTCCTACGGGTACAACCCCTTGACGTATGTCTTCCAATTATCGTATAGCGCAAGCGCCCACATCGCTGGGCCCCCAGATCAGTGTTCTGTCGCTATTGAGAACTGACGGTACCAGAGGCCCGATTAATCCACGTTTCAGGGAAGGTTGGCACCCCGCTATTAAAAAGAACTGGGTGATTTTGGTATCCGTTAAAACGCGGCATGATTAACGGTCCTATTTCATTGACATAGATGAGGCTTAACTTTTGCCGGTCAGCCTCGGAATAGTTTGCTCTTTTC
+
I)8I';:655:<I(%4H'78768937F&78758;I.'7I/'5F&2I(I)I)998G'7H'68;628<937559I(8489:I)I)E&7I1(484I)8;8:;I(:G'I2(;42;=:256I/'I)'7:I/'(77I(I;+&I);;4>8774:5I)I(I(I)2>8839:7448:I(467I0'56429;:2I-&II5,'57<3:6469I'79566:696I(486I(:7732I(6>I)775I(I4);=I*E&9I(9:4I.'79I0'I'I(H'F'94I7*&6484I)II2*&7I(8;I4)6;6I8*&H'387I(<I(I9*&65:H'5:4;>F'I'<I(<H'96I/'66I(886597367:7G'@H'I)7I:+&8I)I)57;;I'85I(I)9<4I1(866:I>,'@
@simulated.297
GACTATAAGTCGTCGGTCGCTCGCATATCTAGACACCTACCCTGAAGGGCTATCCGGGGTGCATCATGCGTAAGTTTTATGAACAGAGAAGGTCTGAGAAGGCCAGGCGGACACCTGCCTTGAAGTGACGACATGGTAGATCATGTGTAGCTTGCTCGCTCTACTTTGTGTATACTCACGATCTGGGTAGTCACGGGATAGCCTTTAAATAACCATGCAACCGTAGATTATCCTACGCGCGATGACAGTAAGTCCATTTATGGTCGCCTCTCCGATGCTAGCGGACGTGACTAGATTGAGTCTGTGCAAATCCTTACTAGGGACGCCGGGGGTCTGGTCGAACAGGTACCTGTATGACTTCATGTATAGGTGGGAGAAAGACAGTATTCGTGAGTGGGCTGAGTAAATAGATACTAAGGACCGACAG
+
96897:I(67=3@5F&7586;5758;1664797<9I'03I/'95I(I3(;578I)I8*&649:483;595<I'4I8*&5>>I)5976:I'I';=6458I)I,H';I(4I(:49I)?8I(G'6I)849:58:;5>I(9958<679<87:867I(=6:<0;43=5:I0'>499>5:5767436758I7*686=864I/'5253F'I-&I.&;I(F'7::4I(F';5;;:I)17I(8=69D9789<<64:69I'65H'6I/'49H'697I'9:8H'5778956;7F'99978946:66I(78<:>37832I,&4I(I(9;64I2(:8;I*II6,':45H'<=:I(98I(43I'5978895<I(<7:7=;:7I(9I/'98I.';25458;E&565799:I0'<3188&I-&47;56516I)I'6H'49459
@simulated.298
TAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCATGTTGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATTGCAAGGTTTGATGGGTTGGTCATCTCGACATCCATCTTACCAAGTTGTAGTTATCAGCGCTGAGTCCTGTCTCGGAACTAGGGTTTGCAGACGGACAGCCTTGGTACATTAAGCTACTCGGGCGCCCGCCAAGGCTTGCCGATGCATGTTTCTGCTGAGGGGTCCGCCTATAAGTGACACTGTCCTGAACTCAGATAAGACGGGTGACTGCCAGGTGGGTGGTGAAAAACACGTGGA
+
9I(08H';<I/'9II;/)&6I=,'I(5=:6:257I):5:I/'89I)563H'9;993I(4:I)9:44G'667468729I)5944;H';76I(98I)I(7I0'7I(47:350II:.)&9859;:<;8;I*:297I,8B6I(<I(99<4I'915<I:+&8I(I2(985H'846I(I(5<I(I(I0'5:5I/'I(I(7786:6::7469I,6<;G'6G'H'4H'5758I'7D56788946341I)57(9:5G'I(596I/'I2(14;679H'5658I)I(I(8652I'I'9924174I0'74I/'5I+I(I(4I(9F'8669=387I.';69:7=6I;+&8I(6I)73;I,:=9<374784I(49I'7:97-:5E&555I-&448)72I(4I(4I1(8I(67II3*&67353I(1
@simulated.299
CATATAGGAGAGCACATACACCGGTGGGTAATACGCGTTACACCGTGGGCGTCTTAACCCTACCGGCAAGCCTACCATCAAGTAATGGAATGATATCCTGCGGGCCCTTCTTTAGTTTCTCGCTAATACGATATTATCCCATTCAGTATGTATTCAATCTAGGTTAGCAGATGCCTAGCAGGGTCTTGACGGTAATAATGCGTGGTTCAAAGGACTTACGGGGAACGTGCACGACTCACCACAAAAATTTACCGTCACAGGTGCGAACTCATAATCCACACGCTCTGGATCCGTATCGGATGGGACCTTTAGAATGTTCCGTTTCCCGTCAACTTGCGCAACGTTAGAGATCATAGGAAATGGGTATGAACCGCTAGTGTGCGCGTGTAGTC
+
:78197I+76:;899878:;I(I(7I0'9I(498515I)6;5I'89I/'5887H'I(I3(4:I(I(2G'6I(;5G'649H'64I(2G'E&9554:8F&77:I/'I/'H'/I-&=1I.&379:9:H'87<576=H':>I/'8I(9684/6647I)7I(9:75H'I(87?9<673I(;6<88I0':6I)5:5I*7I(5I'488=;F'I)5I.&I)66I(86I<,&I(9977387391469I(46II3*&I/'<F'755887F&:8:6I';68;7I(7H'9948:@>:>I(5:I'&65<6I'76I.&9I*I-&83G'47I(E&5I/'I/'7;7I(9I(>;26I(79I(4:76:65><:I*I.&6I.&9857I'H'614475=898565627:75:
@simulated.300
AGCAAACGATTAAGCCGAAAAAGATCACCTCCTTCATTCACCTATTATCAGTTTACTTGCTCTATGTATCCGTTTAGTGGCGGGGATGACTTGCGGCCATCCAATGTCTGCAATATGGAAGCGTCGTATCATGGCAAGACGAACAGAACGGGTTCCAGAGTTGCCGTGCATTACTGTCCGAGCAAGCTGACTGGGTCCCATCGCAGTGGAGTAATGTTGAGGGTCCCCCCATTTTCCACATCATGAAGACGGGCGTTCTGTTCGTGAGGCGAAGTGCGGCTCGCAGTGCCTGTCTCCAGTGTTGTCCAAGTTTACCAGCATACCCCCCACGTATGACTAATGCACCCGACTTCGGTCGCTTCACTCCCCAGGAAATCACCGCTAATTGCA
+
:61I/'766I,I)6I'%II3+'59;37I(=I'G'63I(25I)79G'79>99I.'59I(79:376967<8I(5I.'26:I(8I;+&;=889H'86G'I(79H'I(7555947I(394I(I';569965637:2H'8H':8<;I)7<9H'8I-&I(I*77=;I'8I'87677H'74<87H'2148F'9:6<826I-&7I/'9:7:::&8I(535I(19I(43I.'2II;/)&8I<,&I'8<59456<I)96;I.'34I(9:5H'93:97I'66I)7578I(7854669<5I(58668I)6)65I(6:I(I(8I-&8I)976845II9.)&:6:793<=84I(5;7<I-&4:9I)6H';59=H'63=6I8*&8D&I3(756I(5:<F'F';2:
